Clinical trials: Bipolar
Tobacco Dependence, Schizophrenia
The Appeal and Impact of E-cigarettes in Smokers With SMI
This study will evaluate behavioral and psychological appeal, toxicity, and effect of e-cigarettes on smoking behavior and nicotine addiction in chronic smokers with serious mental illness (SMI) who have failed to quit smoking.
- Conditions
- Tobacco Dependence, Schizophrenia, Bipolar Disorder, Schizoaffective Disorder
- Trial name
- NCT03050853
- Testing
- E-cigarette
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mood Disorders, Depressive Disorder
An Innovative Master Platform for Clinical Trials in Mood Disorders
Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match the right treatment to an individual person.
- Conditions
- Mood Disorders, Depressive Disorder, Bipolar and Related Disorders
- Trial name
- ENABLE (NCT06408012)
- Where
- 9 sites in Canada
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Juvenile Bipolar Disorder Outpatient Program
This is an outpatient program for children and adolescents with bipolar disorders. The naturalistic approach of the program will allow a proper investigation of the disorder, assessment of environmental and biological factors…
- Trial name
- ProCAB (NCT01000402)
- Testing
- Psychopharmacotherapy
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Bipolar Disorder, Depressive Disorder
Spot Depression Study
This study aims to identify signs of depression and bipolar disorder by measuring changes of certain molecules (biomarkers) that can be detected in dried blood spots.
- Trial name
- NCT02804867
- Testing
- Online questionnaire and self-administered blood spot
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Psychosis, Schizophrenia Disorders
DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in Psychosis
Disorganized speech, language and communication, also called 'formal thought disorder,' is a key part of severe mental illnesses like psychosis and mood disorders.
- Conditions
- Psychosis, Schizophrenia Disorders, Bipolar Affective Disorder, Depressive Disorder
- Trial name
- DIALOG (NCT06978465)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Depression, Bipolar Disorder
Brain Imaging in Depression
The purpose of this study is to use brain imaging technology to examine the role of certain brain receptors and the nervous system chemical acetylcholine in major depression.
- Trial name
- NCT00050700
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Anxiety
Mood Lifters: A Self Help Program
Large scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial based problems are urgently needed.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT02558075
- Testing
- MoodLifters Sessions
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bipolar Disorder
Bioequivalency Study of 300 mg Lithium Carbonate Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane lithium carbonate 300 mg extended release tablet formulation compared to Solvay's Lithobid 300 mg extended release tablet under fasting conditions using a…
- Trial name
- NCT00601536
- Testing
- Lithium
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Stroke, Muscle Hypertonia
Antagonist Activation Measurement at the Ankle Using High-density and Bipolar Surface EMG in Chronic Hemiparesis
In chronic hemiparesis, abnormal antagonist muscle activation in the paretic lower limb contributes to impair ambulation capacities.
- Conditions
- Stroke, Muscle Hypertonia, Spasticity, Muscle
- Trial name
- CC2017 (NCT06099132)
- Testing
- Electromyographic measurements
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Bipolar Disorder
A Double-Blind, Placebo-Controlled Study of Galantamine to Improve Cognitive Dysfunction in Bipolar Disorder
The purpose of this study is to determine if galantamine augmentaion improves cognition in euthymic bipolar patients. In addition, the effect of galantamine on clinical measures of functioning and psychopathology will also be…
- Trial name
- NCT00195845
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Bipolar Disorder
Sleep Deprivation and Advancement of Sleep Period as Treatment for Bipolar Depression.
The purpose of this study is to determine if sleep deprivation and sleep phase advancement is effective treatment of bipolar patients in a depressive phase.
- Trial name
- NCT00229151
- Testing
- Sleep deprivation and sleep phase advancement, usual treatment
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Bipolar Disorder
FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
This study will assess the effects of bipolar disorder on brain activity and will determine if medication changes the brain activity in people with bipolar disorder.
- Trial name
- NCT00596622
- Testing
- Lithium
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Partum Depression, Bipolar Disorder
Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers
Through a recent cross species translational experiment, researchers have identified a set of epigenetic marks capable of predicting postpartum depression with greater than 85% accuracy.
- Trial name
- NCT03638687
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anxiety, Depression - Major Depressive Disorder
Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections: Translating Epidemiology to Deep-phenotyping.
The study protocol was submitted to ERA-NET NEURON for funding on 28/06/2023. Description of the Israeli responsibilities was extracted from the full submitted research protocol. The protocol includes two studies (CHS1 and CHS2).
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Bipolar, Schizophenia Disorder
- Trial name
- Viral-MI (NCT07453420)
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Bipolar, Depression
Adjunctive Lisdexamfetamine (LDX) in Bipolar Depression
The specific aim of this study is to evaluate the efficacy and tolerability of lisdexamfetamine in the adjunctive treatment of bipolar disorder.
- Trial name
- NCT01131559
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lindner Center of HOPE
Major Depressive Disorder, Bipolar Affective Disorder, Currently Depressed, Moderate
The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)
Patients belonging to Group 1 (Major Depression) and 2 (Bipolar Disorder) will be tested with psychometric and functional scales at baseline (T0) and after 4 weeks of pharmacological therapy (T1), to evaluate clinical and…
- Trial name
- RONIN (NCT06131268)
- Testing
- Venlafaxine
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Epistaxis Nosebleed
Coblation Versus Bipolar Diathermy in Management of Refractory Idiopathic Recurrent Anterior Epistaxis in Children.
The aim of this study is to compare the outcomes of coblation technique versus bipolar technique in management of RAE in children regarding the following: 1. Efficacy of each method to stop bleeding. 2. Technical feasibility. 3.
- Trial name
- NCT06651840
- Testing
- bipolar diathermy "Standard technique"., coblation technique.
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bipolar Disorder
High Deductible Health Plans and Bipolar Disorder
Using eleven years (2004-2014) of claims data from the largest US commercial health insurer, the investigators will assess the impact of switching into high-deductible health plans (HDHPs) on outcomes for patients with bipolar…
- Trial name
- NCT02560701
- Testing
- Patient Interview
- Volunteers
- 350,823 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Bipolar Disorder
Interval Training in Bipolar Disorder
Our main objective will be to evaluate the chronic effects (12 weeks) of high-intensity interval training compared to moderate intensity (same total work) on reducing the symptoms of bipolar disorder, cortical changes, as well as…
- Trial name
- HIIT (NCT02498730)
- Testing
- Interval Training, Continuous Training, Control
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences