Clinical trials: Bipolar Disorder Mild
Bipolar Disorder
Olanzapine vs. Comparator and Placebo in the Treatment of Patients With Bipolar I Disorder
The goals of this study are: A. To determine whether olanzapine can help patients with bipolar disorder who currently have mild to moderate mania. B.
- Trial name
- NCT00094549
- Testing
- olanzapine, divalproex sodium
- Where
- 42 sites in United States, Lithuania and 3 more
- Volunteers
- 500 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Bipolar Disorder
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
The purpose of this research is to measure brain activity in individuals with mood disorders and memory problems using a simple, safe, and noninvasive method called functional near-infrared spectroscopy (fNIRS).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
- Trial name
- NCT06897670
- Testing
- Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Dementia, Bipolar Disorder (BD)
Lithium for Prevention of Cognitive Declining in Mood Illnesses
INTRODUCTION: Mood disorders, bipolar disorder and recurrent unipolar depression, are among the most common mental health conditions worldwide.
- Conditions
- Dementia, Bipolar Disorder (BD), Depression - Major Depressive Disorder, Mild Cognitive Impairment (MCI)
- Trial name
- NCT06662526
- Testing
- Trace lithium dose plus treatment as usual
- Where
- 2 sites in Chile
- Volunteers
- 250 people
- Sponsor
- University of Chile
Bipolar Disorder, Cannabis Use
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
This research study evaluates the effects of an FDA-approved medication Gabapentin in individuals with Bipolar Disorder who smoke marijuana.
- Conditions
- Bipolar Disorder, Cannabis Use, Schizoaffective Disorder, Bipolar Type, Bipolar I Disorder
- Trial name
- NCT05064319
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical University of South Carolina
Bipolar Disorder
Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms
The purpose of this research study is to evaluate the safety, tolerability, and efficacy of quetiapine compared to placebo (sugar pill without medication) in the treatment of bipolar disorder with moderate to severe hypomania or…
- Trial name
- NCT00277667
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Lindner Center of HOPE
Senile Plaques, Tau Proteins
Cognitive, Morphological and Neurobiological Progressive Aspects in Bipolar Disorders in the Elderly: Toward to a Neurodegenerescence Detection?
The purpose of this study is to identify association between cerebrospinal fluid Alzheimer's Disease's neurodegenerescence biomarkers (tau, ptau, Aß40 and Aß1-42) and occurrence of cognitive deficits in older patients with…
- Conditions
- Senile Plaques, Tau Proteins, Alzheimer Disease, Bipolar Disorders
- Trial name
- BIPAGE (NCT02843906)
- Testing
- Lombar Punction, Magnetic Resonance Imaging (MRI), Positron-Emission Tomography (TEP) /(FDG)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Grenoble
Bipolar Spectrum Disorder With Moderate-to- Severe Hypomania or Mild Mania
Study of Divalproex Extended Release Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomania or Mild Mania
The purpose of this research study is to evaluate the safety, tolerability, and efficacy of divalproex extended release compared to placebo (sugar pill without medication) in the treatment of bipolar disorder with moderate to…
- Trial name
- NCT00278772
- Testing
- Divalproex
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Lindner Center of HOPE
Bipolar Disorder, Bipolar I Disorder
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Bipolar Type I Disorder
- Trial name
- NCT04211428
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Alzheimer Disease, Mild Cognitive Impairment
Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders
The primary objective of the study is to evaluate the feasibility of eliciting continuous narrative speech in different neurodegenerative and psychiatric indications, using remote, self-administered speech tasks, as measured by…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia With Lewy Bodies, Dementia, Vascular
- Trial name
- RHAPSODY (NCT04939818)
- Where
- 2 sites in United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Novoic Limited