Clinical trials: Birth; Induced
Term Pregnancy, Doppler Parameters
Relationship Between Delivery Route and Fetal Complications With Doppler Indices and CPR Parameters
Term pregnancies within their 37-41 gestational week, who were planned to undergo induction of labor, were included in the study.
- Conditions
- Term Pregnancy, Doppler Parameters, Induction of Labor, Fetal Complications
- Trial name
- Doppler (NCT04158609)
- Testing
- Doppler flow indices assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Induced Vaginal Delivery
Potential of Vojta's Reflex Locomotion as a Pre/Induction Method for Uterine Activity: a Pilot Study
The Vojta's method is neurophysiological rehabilitation method used to support and induce reflex responses of locomotor and vegetative system.
- Trial name
- NCT06339528
- Testing
- Vojta's Reflex Locomotion
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Nulliparous Women Who Scheduled for Labor Induction, Pregnancy
Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)
The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex…
- Trial name
- RAPID-DS (NCT07717502)
- Testing
- Sequential Cervical Ripening, Inpatient Combined Cervical Ripening
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Ochsner Health System
Phenylephrine, Cesarean Birth
Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to…
- Trial name
- NCT07420127
- Testing
- Phenylephrine bolus 75 micrograms, Phenylephrine bolus 50 micrograms
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Birth Asphyxia
Asphyxia Associated Metabolite Biomarker Investigation 2
Follow-up of participants of AAMBI1 study at age of at least 2 years. AAMBI1(ClinicalTrials.gov ID: NCT03354208): Verification of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia.
- Trial name
- AAMBI2 (NCT04714502)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- InfanDx AG
Maternal Health, Pregnancy
Understanding the Role of Doulas in Supporting People With PMADs
Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility.
- Conditions
- Maternal Health, Pregnancy, Delivery, Obstetric, Self Efficacy
- Trial name
- NCT05763537
- Testing
- Standard Doula Care Plus PMAD Intervention, Standard Doula Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Montana
Premature
Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants
A comprehensive analysis of the impact of exogenous enteral DHA and ARA supplementation on lipid metabolism including the production of downstream derived mediators and how this impacts important biological pathways such as…
- Trial name
- NCT05380401
- Testing
- Enfamil® DHA & ARA Supplement for Special Dietary Use
- Where
- 7 sites in United States
- Volunteers
- 328 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cesarean Delivery
A RCT of Labor Induction at 39 Weeks in Low - Risk Women in China
The investigators are committed to identifying the optimal timing of delivery for low-risk pregnancies. While current guidelines typically recommend induction at 41 weeks, emerging evidence suggests that elective induction at 39…
- Trial name
- LIRIC (NCT07082530)
- Testing
- Labor Induction at 39 Weeks, Expectant management
- Where
- China
- Volunteers
- 1,074 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Induced; Birth, Induction of Labor Affected Fetus / Newborn
Cervical Ripening With Foley Bulb Versus Dilapan-S at Home
DILAPAN-S® was FDA-approved for pre-induction cervical ripening in 2015. Since that time, there have been limited studies comparing its efficacy, safety, and patient satisfaction to other mechanical cervical ripening techniques.
- Trial name
- GOHOME (NCT04739683)
- Testing
- Foley bulb placement, DILAPAN-S® placement
- Sponsor
- Christiana Care Health Services
Previous; Cesarean Section, Cicatricial, Complicating Pregnancy or Childbirth, Affecting Fetus or Newborn, Prelabor Rupture of Membranes
Balloon Induction of Labor in PROM for TOLAC
A prospective randomized controlled trial to evaluate the safety and efficacy of labor induction with a double balloon catheter (Atad Ripener Device) in women desiring TOLAC (trial of labor after cesarean) with PROM (pre labor…
- Trial name
- BILROM-TOLAC (NCT03399266)
- Testing
- Double Balloon catheter for induction of labor
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Labor Pain, Induced; Birth
Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor
A total of 60 parturients undergoing induction of labour will be consented to participate in the study where they will be randomized to receive either spinal fentanyl (20 µg) or epidural analgesia (fentanyl 100µg and lidocaine 80…
- Trial name
- NCT04645823
- Testing
- Fentanyl Citrate, Lidocaine 1% Injectable Solution
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Women's Hospital HUS
Substance Use Disorders, Simulation Training
Interprofessional Simulation Program for Clinical Resilience and Empathy: Project INSPIRE
The goal of this clinical trial is to develop and evaluate INSPIRE, an intervention for healthcare teams to improve care for individuals with substance use disorder (SUD) during their peri-delivery care.
- Conditions
- Substance Use Disorders, Simulation Training, Pregnancy Related, Patient-centered Care
- Trial name
- INSPIRE (NCT07707115)
- Testing
- INSPIRE
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Respiratory Distress Syndrome, Newborn, Premature Birth
SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants.
SURFAXIN® (lucinactant) treatment will be examined in very low birth weight infants to prevent development of chronic lung disease, commonly known as bronchopulmonary dysplasia (BPD), in premature infants who have required…
- Conditions
- Respiratory Distress Syndrome, Newborn, Premature Birth, Bronchopulmonary Dysplasia
- Trial name
- NCT00215540
- Testing
- Lucinactant 175 mg/kg, Lucinactant 90 mg/kg
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Windtree Therapeutics
Fetal Macrosomia
DAME: Induction of Labor or Waiting for Suspicion Fetal Macrosomia
Aim of the study :The major aim is to evaluate the effectiveness of the induction of labor in case of fetal macrosomia on the reduction of neonatal traumatism risk.
- Trial name
- NCT00190320
- Testing
- Induction of labor vs waiting
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chemotherapy-induced Nausea and Vomiting
Study of the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Fosaprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Children (MK-0517-029)
The purpose of this study was to determine the appropriate dosing regimen of fosaprepitant, when administered with ondansetron (with or without dexamethasone), for the prevention of CINV in children from birth to <17 years of…
- Trial name
- NCT01697579
- Testing
- Fosaprepitant, Ondansetron, 5-hydroxytryptamine 3 antagonist
- Volunteers
- 240 people
- Sponsor
- Merck Sharp & Dohme LLC
Neonatal Oxygen Desaturation, Premature
Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants
This research study is being done to investigate the effect of changing an infant's body position on how hard the baby works to breathe, the baby's oxygen level, the baby's carbon dioxide level, the baby's lung volume, the baby's…
- Conditions
- Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
- Trial name
- NCT05968586
- Testing
- Body positioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Prematurity; Extreme, Inflammation
Anakinra for Preterm Infants Pilot
Phase I/II study of anakinra to prevent the impact of perinatal inflammation in extremely premature infants.
- Trial name
- NCT05280340
- Testing
- Anakinra
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 25 people
- Sponsor
- Monash Medical Centre
Induction of Labor
Induction of Labor With a Foley Balloon Catheter: Inflation With 30ml Compared to 60ml
The rate of labor induction is rising throughout the United States for a variety of reasons. Medical conditions that lead to increased risk of prolonging the pregnancy to both mother and fetus are not infrequent.
- Trial name
- NCT00451308
- Testing
- Induction of labor with foley balloon - 60cc of saline, Induction of labor with foley balloon with 30cc
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Francisco
Preterm Birth, Bronchopulmonary Dysplasia
Improving Prematurity-Related Respiratory Outcomes at Vanderbilt
The goal of IMPROV is to identify molecular mechanisms that contribute to lung injury and long-term breathing problems in preterm infants by investigating two interrelated biochemical pathways: the urea cycle-nitric oxide pathway…
- Conditions
- Preterm Birth, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
- Trial name
- IMPROV (NCT01460576)
- Where
- 2 sites in United States
- Volunteers
- 253 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Hypertension, Bronchopulmonary Dysplasia
Neolifes Heart - Pulmonary Hypertension in Preterm Children
NeoLifeS is a cohort follow up study that prospectively collects data of regular care of children born preterm in the University Medical Center Groningen (UMCG) and aims to improve the quality of care for these children.
- Trial name
- NCT02729844
- Where
- Netherlands
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen