Clinical trials: Birth, open to volunteers
Healthy
DNS: Face-to-face and Telerehabilitation
This study aims to compare the effects of Dynamic Neuromuscular Stabilization (DNS) exercises delivered face-to-face (YDNS) and via tele-rehabilitation (TDNS) on respiratory function, balance, posture, core endurance, and deep…
- Trial name
- NCT07775560
- Testing
- DNS Exercises via Telerehabilitation, Face-to-face DNS Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istinye University
Diabetes Type 1
Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study)
Up to one in two adults with type 1 diabetes find living with and managing diabetes to be emotionally challenging. This 'emotional side' of diabetes - feeling worried, frustrated, overwhelmed, sad, burnt-out - is called diabetes…
- Trial name
- NCT07193446
- Testing
- D-stress study: The detection, prevention and management of diabetes distress for adults living with type 1 diabetes.
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Preterm Birth
PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol]
PLATIPUS is an adaptive platform trial aimed at improving the health of infants born preterm (before 37 weeks' gestation). PLATIPUS will compare how different treatments and care provided to pregnant women and people at risk of…
- Trial name
- PLATIPUS (NCT06461429)
- Testing
- Erythromycin, Amoxicillin and Erythromycin, Azithromycin
- Volunteers
- 100,000 people
- Sponsor
- University of Melbourne
Fetal Membranes, Premature Rupture, Preterm Premature Rupture of the Membranes
PPROM Registry (Preterm Premature Rupture of Membranes)
Preterm Premature Rupture of Membranes (PPROM) before 37 weeks of pregnancy is responsible for 40% of preterm births in the United States.
- Conditions
- Fetal Membranes, Premature Rupture, Preterm Premature Rupture of the Membranes, Oligohydramnios, Premature Birth
- Trial name
- NCT02997345
- Testing
- There is no intervention associated with this study.
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- American Alliance for pProm Support
Post-traumatic Stress Disorder (PTSD), Postpartum Mental Health
A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth
This study aims to explore whether playing the computer game Tetris can reduce PTSD symptoms in women who have undergone emergency caesarean births.
- Trial name
- NCT07290127
- Testing
- implementation of a brief computer-based intervention "Tetris"
- Where
- Japan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyoto University, Graduate School of Medicine
Postpartum Exercise, Cardiometabolic Health
Exercise to Improve Heart and Metabolic Health After Childbirth in Women at High Risk for Preeclampsia
Women who develop hypertensive disorders of pregnancy have an increased risk of cardiovascular disease later in life. Whether exercise during the postpartum period improves cardiometabolic health in this population remains…
- Conditions
- Postpartum Exercise, Cardiometabolic Health, High Risk for Preeclampsia, Randomized Controlled Trial
- Trial name
- NCT07921173
- Testing
- Postpartum Exercise Program
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Nursing Education, Social-Emotional Learning
Augmented Reality Virtual Patient Simulation to Enhance Social-Emotional Competence and Self-Efficacy in Nursing Students
This randomized crossover teaching practice study evaluates whether smart technology and media-integrated friendly childbirth education can improve nursing students' social-emotional competence and self-efficacy.
- Conditions
- Nursing Education, Social-Emotional Learning, Self-Efficacy
- Trial name
- SEL-AR (NCT07874061)
- Testing
- VP-I, VP-AR
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Preterm Birth, Activity Restriction
DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention
DE-RESTRICT is a pilot study testing whether a strategy to reduce the use of activity restriction and bedrest in pregnancy is acceptable, appropriate, and feasible for prenatal care providers, and whether it changes how often…
- Conditions
- Preterm Birth, Activity Restriction, Bed Rest, Low-Value Care
- Trial name
- NCT07698483
- Testing
- Multicomponent deimplementation strategy
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cerebral Palsy
Trends in Prevalence and Comorbidities of Children With Cerebral Palsy in Norway
Many studies have reported that the prevalence of cerebral palsy (CP) has been relatively stable and is mainly due to events before birth and therefore cannot be prevented.
- Trial name
- NCT03413566
- Testing
- Clinical diagnosis
- Volunteers
- 707,916 people
- Sponsor
- Sykehuset i Vestfold HF
Infant, Newborn, Gut -Microbiota
Infant Microbiota Restoration With Maternal Microbes
The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants.
- Conditions
- Infant, Newborn, Gut -Microbiota, Gut Dysbiosis, Cesarean Delivery Affecting Newborn
- Trial name
- MaMi (NCT07212361)
- Testing
- Probiotic
- Where
- 2 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Health Care Costs, Delivery of Health Care
Advancing Decisions About Virtual Service Encounters
Expanded availability of virtual care encounters in Primary Care provides new opportunities to improve Veterans' outcomes by aligning encounter modalities with their needs and preferences.
- Trial name
- ADViSE (NCT06539988)
- Testing
- Clinician Coaching Sessions, Personalized text messages to patients
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- VA Office of Research and Development
Sexual Behavior, Adolescent Behavior
Rigorous Evaluation of Let's Talk Birth Control
The goal of this cluster-level randomized controlled trial is to evaluate the impacts of Let's Talk Birth Control, a clinical decision support intervention for adolescents that consists of a printed contraceptive decision aid…
- Trial name
- NCT06670066
- Testing
- Let's Talk Birth Control
- Where
- 2 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Child Trends
Postoperative Pain After Cesarean Section
Efficacy and Safety of Photobiomodulation for Postoperative Pain After Cesarean Section
Postoperative pain following cesarean section remains a major clinical challenge that can impair early maternal recovery, delay ambulation, and interfere with newborn care.
- Trial name
- BIOLUZCE (NCT07863960)
- Testing
- Photobiomodulation Therapy (MitoQUAD® Belt System)
- Where
- Honduras
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Delivery Outcomes
Interdisciplinary Practice Bundle for Second-Stage of Labor and Clinical Outcomes
This study aims to assess the effect of implementing an interdisciplinary practice bundle during second-stage of labor on clinical outcomes.
- Trial name
- NCT07055490
- Testing
- Interdisciplinary Practice Bundle
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Premature Birth
EEG and NIRS in Preterm Infants
Experimental cross-sectional study of a single application (vojta therapy or massage) in preterm and non-preterm infants to test whether there are differences in brain activation and oxygenation that occur with both techniques…
- Trial name
- NCT05410340
- Testing
- Vojta Therapy, Massotherapy
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
GBM, Glioma Glioblastoma Multiforme
WBSI Guided Personalized Delivery of TTFields
This research study is for Glioblastoma (GBM) patients who will be beginning Optune as part of their clinical care, which is a novel treatment that utilizes - tumor treating fields (TTFields), (aka, electrical therapy), which has…
- Conditions
- GBM, Glioma Glioblastoma Multiforme, Tumor, Brain
- Trial name
- NCT05086497
- Testing
- Whole Brain Spectroscopy Imaging Array Mapping Layout
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Apnea of Prematurity
Caffeine Citrate to Improve Neonatal Outcomes.
The goal of this clinical trial to learn what dose/s of caffeine citrate works to treat preterm born babies who have episodes where they stop breathing.
- Trial name
- BabyCCINO (NCT06972849)
- Testing
- Caffeine citrate
- Volunteers
- 3,900 people
- Sponsor
- University of Melbourne
Type 1 Diabetes (T1D), Obesity (Disorder)
Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System
Overweight and obesity are frequent in adults with type 1 diabetes (T1D), with prevalence exceeding 50% in recent studies. Excess weight in T1D is associated with higher cardiometabolic risk and therapeutic challenges, while…
- Trial name
- KET1D (NCT07185555)
- Testing
- VLEKT
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Neonates and Preterm Infants, Neonates or Premature Babies
Prospective Study of the Feasibility of Brain Connectivity Imaging by Functional Ultrasound Imaging (fUS) in Newborn Infant
Neurodevelopmental disorders (NDD) affect how the brain develops and can lead to lifelong difficulties with movement, learning, behavior, and thinking.
- Trial name
- CONEXUS (NCT06940713)
- Testing
- Imaging Time
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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