Clinical trials: Birth
Premature Birth
Preterm Lung Function and Exercise Response Measured by OEP
This study will explore lung function and respiratory health in school-aged children who were born prematurely at <32 weeks gestation.
- Trial name
- NCT04239287
- Testing
- Lung function + exercise tests
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Respiratory Aspiration, Pregnancy
Gastric Sonography in the Fasted Term Pregnant Patient for Elective Cesarean Delivery
Food residue in the stomach of patients scheduled to have surgery is considered a major risk factor for pulmonary aspiration of gastric contents.
- Trial name
- NCT01980121
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Vaginal Delivery
Measurement of the Fetal Occiput-spine Angle During the First Stage of Labor as Predictor of the Outcome of Labor
2D trans abdominal ultrasound was done during the first stage of labor. If fetal position is occiput anterior and fetal presentation is vertex, two dimensional sagittal picture of the fetal head and upper spine was acquired and…
- Trial name
- NCT03264599
- Testing
- transabdominal ultrasound
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Cairo University
Breastfeeding, Postnatal Depression
Mother and Late Preterm Lactation Study
Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and…
- Conditions
- Breastfeeding, Postnatal Depression, Stress, Psychological, Preterm Infant
- Trial name
- MAPLeS (NCT03791749)
- Testing
- Breastfeeding Support
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College, London
Pregnancy, Prematurity
Vaginal Probiotics During Pregnancy After Premature Rupture of Membranes
The goal of this clinical trial is to compare the microbiota of preterm babies born after premature breaking water with full-term babies microbiota.
- Conditions
- Pregnancy, Prematurity, PPROM
- Trial name
- PROBPROM-Pilot (NCT06878443)
- Testing
- Vaginal probiotics
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Anterior Wall Acute Myocardial Infarction
Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
The primary objective of the study is to collect confirmatory data supporting the safety and effectiveness of SSO2 Therapy in treatment of anterior acute myocardial infarction (AMI) patients who have undergone successful…
- Trial name
- IC-HOT (NCT02603835)
- Testing
- SSO2 Therapy
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- TherOx
Cesarean Section Wound
Bilevel Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Analgesia After Cesarean Delivery.
Optimizing analgesia after cesarian delivery is an essential element of enhancing maternal recovery.A multimodal analgesic approach incorporating truncal blocks can provide effective pain relief with minimal side effects for both…
- Trial name
- NCT07137208
- Testing
- ESP block, TAP Block, Bupivacaine injection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cerebral Palsy, Prematurity
NEO Rehab Program for Premature Infants at Risk for Cerebral Palsy
The goal of this project is to investigate the acceptability, feasibility and fidelity of an innovative NICU rehabilitation program that will include six multimodal, gestational age (GA) appropriate, parent-administered…
- Conditions
- Cerebral Palsy, Prematurity, Early Intervention, Family Centered Care
- Trial name
- NCT04330859
- Testing
- NeoRehab Bundle, Routine care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Virginia
Pregnancy
Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis
Background. Anomalies of the vaginal flora (bacterial vaginosis, BV) are associated with an increased risk of late abortions and preterm birth.
- Trial name
- PREMEVA (NCT00642980)
- Testing
- Clindamycin
- Where
- France
- Volunteers
- 3,105 people
- Sponsor
- University Hospital, Lille
Pregnancy, Urinary Incontinence (UI)
Effects Of Tele-PFME On Urinary Incontinance, Pelvıc Floor Functions and Childbirth
The aim of this study is to examine the effect of pelvic floor exercises performed via prenatal tele-rehabilitation on the following issues: 1.
- Conditions
- Pregnancy, Urinary Incontinence (UI), Childbirth, Tele-rehabilitation
- Trial name
- Tele-PFME (NCT07753746)
- Testing
- Tele-rehabilitation, Home based-Non supervised PFME
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Contrast-induced Acute Kidney Injury (CI-AKI)
Hemodynamic Effects Of Impella On Renal Circulation And Risk Of CA-AKI Among Patients Undergoing Protected PCI
Patients undergoing Percutaneous Coronary Intervention (PCI) are exposed to the risk of suffering from a damage to the kidneys which goes under the name of Contrast-Associated Acute Kidney Injury (CA-AKI), which is more common if…
- Trial name
- NCT04928118
- Testing
- Evaluate the blood flow and pressure into kidneys
- Sponsor
- Virginia Commonwealth University
Referral and Consultation, Telemedicine
Electronic Referral and Booking of Outpatient Day Case Surgery Compared With Traditional Referral Routines.
We want in this study to investigate the cost-effectiveness and waiting time of direct electronic referral and booking of outpatient surgery compared to the traditional patient pathway where the patient is seen at the outpatient…
- Conditions
- Referral and Consultation, Telemedicine, Surgery, Outpatient, Surgery, Day
- Trial name
- one-stop (NCT00692497)
- Testing
- one stop (Electronic standardised referrals and appointment bookings)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- University Hospital of North Norway
Breast Cancer Female
FErtility, PrEgnancy, contRaceptIon After Breast Cancer in France
FErtility, PrEgnancy, contRaceptIon after breast Cancer in France
- Trial name
- FEERIC (NCT03884413)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Epidural Analgesia, Nulliparous Pregnant
Evaluation of a Protocol Posturalchanges in Women Giving Birth With Epidural Analgesia. Clinical Trial.
. The pain that occurs during labor is controlled in our environment through epidural analgesia. This mainly generates a sensory block but also a motor block that suppresses different reflexes physiological factors that…
- Conditions
- Epidural Analgesia, Nulliparous Pregnant, Labor With Postural Changes, Randomized
- Trial name
- NCT05812560
- Testing
- postural changes
- Where
- Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Coronary Artery Disease
Filgrastim for the Promotion of Collateral Growth in Patients With CAD
The purpose of this study in humans with stable coronary artery disease (CAD) treatable by PCI (percutaneous coronary intervention) is to evaluate the safety and efficacy of subcutaneous delivery of recombinant granulocyte colony…
- Trial name
- NCT00596479
- Testing
- Filgrastim (rG-CSF)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fear of Childbirth, Psychosocial Health
Effects of Solution-Oriented Approach on Psychosocial Health, Fear of Childbirth and Postnatal Senses of Security
This study was planned as a randomized controlled experimental study with posttest and control group in order to evaluate the effect of the solution focused approach method applied to primigravidas on psychosocial health, fear of…
- Conditions
- Fear of Childbirth, Psychosocial Health, Pregnancy, Postpartum
- Trial name
- NCT04820296
- Testing
- Solution-Oriented Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Apnea of Prematurity
Apnea of Prematurity Results in Respiratory Distress and Cyanosis. Caffeine Citrate Can Treat It.
High-dose caffeine citrate is more effective than low-dose caffeine citrate in the treatment of apnea of prematurity (AOP). The high-dose group showed fewer apnea episodes, higher extubation success rate, lower extubation failure…
- Trial name
- AOP (NCT06905496)
- Testing
- High-Dose, Low Dose
- Where
- Pakistan
- Volunteers
- 114 people
- Sponsor
- Nishtar Medical University
Type 1 Diabetes Mellitus
Automated Insulin Delivery in Elderly With Type 1 Diabetes (AIDE T1D)
A multi-center, randomized, crossover trial consisting of three sequential 12-week periods, with the HCL feature used during one period, the PLGS feature used during one period and SAP therapy (control) during one period.
- Trial name
- AIDE T1D (NCT04016662)
- Testing
- Tandem t:slim X2 with HCL or PLGS
- Where
- 4 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research