Clinical trials: Birth Control, open to volunteers
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Neonatal Intensive Care Units, Premature Infant
Virtual Reality-Enhanced Parent Education in Neonatal Intensive Care
This randomized pilot clinical trial aims to evaluate the effectiveness and feasibility of virtual reality (VR)-enhanced parent education in improving neonatal intensive care unit (NICU) caregiving practices among parents of…
- Conditions
- Neonatal Intensive Care Units, Premature Infant, Parent Education, Virtual Reality
- Trial name
- NCT07410858
- Testing
- Virtual Reality-Enhanced Parent Education
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Jouf University
Postpartum Hemorrhage
TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA
Several randomized, controlled trials, mostly involving women undergoing cesarean delivery, have shown that the prophylactic intravenous administration of 1 g of tranexamic acid after childbirth reduced blood loss.
- Trial name
- TRAAPrevia (NCT04304625)
- Testing
- Tranexamic Acid / Sodium chloride
- Where
- France
- Volunteers
- 1,380 people
- Sponsor
- University Hospital, Bordeaux
Contraceptive Usage, Telemedicine
Telemedicine Contraceptive Counselling (TECC) Versus Standard Care
Overall purpose of the PILOT and RCT: This research project aims to increase access and uptake of contraception after abortion through the systematic development and testing of a new telemedicine service for contraceptive…
- Trial name
- TECC (NCT06682065)
- Testing
- Telemedicine for contraceptive counseling (TECC), Standard Care
- Where
- 2 sites in South Africa
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Reproductive Health, Gestatiaonl Diabetes Mellitus
Exploring Reproductive Health Among Women in Somaliland
Somaliland faces persistently high burdens of maternal and perinatal mortality, with limited population-based data on pregnancy complications, sociocultural influence on maternal health, and women's reproductive health needs…
- Conditions
- Reproductive Health, Gestatiaonl Diabetes Mellitus, Hypertensive Disorders of Pregnancy, Contraception
- Trial name
- PROMISE (NCT07438379)
- Where
- Somalia
- Volunteers
- 808 people
- Sponsor
- University of Hargeisa
Preterm Birth, Caffeine
Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support
The goal of this pilot clinical trial is to test if it is possible to conduct a larger study on the use of caffeine in preterm infants who need help with their breathing.
- Conditions
- Preterm Birth, Caffeine, Neonatal Outcomes
- Trial name
- CARES-Pilot (NCT07456670)
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Queen's University
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Intra-uterine Device Placement
Pain Associated wIth traditioNal Versus uLtrasound guidEd iuS (Intra Uterine System) inSertion
Rationale: The 2019 Belgian Health Survey shows that the combined oral contraceptive pill is the most commonly used form of contraception.
- Trial name
- PAINLESS (NCT07315646)
- Testing
- IUS (intrauterine system) insertion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Third Stage of Delivery
Maternal Outcomes Following Manual Lysis of the Placenta.
Comparison of maternal outcomes following manual lysis of placenta 15 vs 30 minutes after delivery. A primary outcome of the drop in hemoglobin will be compared between the two groups.
- Trial name
- NCT03626844
- Testing
- Manual Lysis of Placenta after 15 minutes (Intervention), Manual Lysis of Placenta after 30 minutes (Control)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Postpartum Period
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are…
- Trial name
- NCT06963047
- Testing
- Ultrasound, Standard care
- Where
- Israel
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Pain Management, Postoperative Pain
PCDD Generation 1 Oral Liquid Acetaminophen Delivery Evaluation
This prospective randomized pilot study evaluates the feasibility, acceptability, and preliminary efficacy of the Patient-Controlled Dispenser and Deactivator (PCDD) Generation 1 system for patient-controlled oral liquid…
- Trial name
- NCT07765238
- Testing
- PCDD Generation 1 system
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC3 (NCT06974032)
- Testing
- Xylocaine jelly 2%, Surgilube
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postoperative Pain After Cesarean Section
Efficacy and Safety of Photobiomodulation for Postoperative Pain After Cesarean Section
Postoperative pain following cesarean section remains a major clinical challenge that can impair early maternal recovery, delay ambulation, and interfere with newborn care.
- Trial name
- BIOLUZCE (NCT07863960)
- Testing
- Photobiomodulation Therapy (MitoQUAD® Belt System)
- Where
- Honduras
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Parenting, Self Efficacy
The Development and Evaluation of a Web-based Childbirth and Parenting Intervention Program
Background: The transition to parenthood is stressful for first-time mothers and fathers and links to adverse health outcomes. Despite Internet use's popularity, an effective web-based, individually-tailored intervention to…
- Conditions
- Parenting, Self Efficacy, Psychological Distress
- Trial name
- NCT04981730
- Testing
- Web-based intervention
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Energy Deficiency Due to Short-term Fasting, Hormonal Contraception
Energy Deficiency on Hormones in Contraceptive Users
The purpose of the present study is to characterize the endocrine and metabolic responses to a modest, short-term energy deficiency (~250 kcal/day) across the menstrual cycle in recreationally active women using different…
- Trial name
- NCT07651800
- Testing
- Energy Deficiency of approximately ~250 kcal/day
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Postpartum Depression, Maternal-Fetal Relations
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes
This randomized controlled trial aims to evaluate the effect of listening to the recitation of Surah Al-Inshirah during the early postpartum period after cesarean birth on women's spiritual well-being, depression levels, and…
- Conditions
- Postpartum Depression, Maternal-Fetal Relations, Spirituality
- Trial name
- NCT07354334
- Testing
- Listening to Surah Al-Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Thin Endometrium, Female Infertility
Intrauterine G-CSF Infusion for Thin Endometrium
Thin endometrium is a condition in which the lining of the uterus is too thin during preparation for embryo transfer. This may reduce the chance of pregnancy and live birth in patients undergoing frozen-thawed embryo transfer.
- Trial name
- GIFT (NCT07692672)
- Testing
- Granulocyte Colony-Stimulating Factor(G-CSF), Normal Saline
- Volunteers
- 620 people
- Sponsor
- Nanjing University