Clinical trials: Bispectral Index
Supratentorial Brain Tumor Surgery
FASt Track in Elective Neurosurgery: the Role of Low Propofol Bis-NOL Guided General Anaesthesia for Full, Early and Safe Awakening
To evaluate the effect of intraoperative sedation dosage on awakening and recovery of consciousness after elective neurosurgical surgery.
- Trial name
- FasTrack (NCT06844838)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
BIS
The Influence Factors of Bispectral Index Values Increment Caused by Sugammadex
Sugammadex administration may increase the bispectral index (BIS) values during general anesthesia. The purpose of this study was to investigate the influence factors leading to increase in BIS value caused by sugammadex…
- Trial name
- NCT06561633
- Testing
- Sugammadex administration
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Jun Zhang
Anesthesia, Drug Interaction
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia
Precision anesthesia is the current trend. The benefits including faster recovery, earlier return to normal activity, increased patient satisfaction and shorter length of stay.
- Conditions
- Anesthesia, Drug Interaction, Anesthesia; Functional
- Trial name
- NCT05525351
- Testing
- Bispectral index (BIS) or Patient State Index (PSI), Propofol, Alfentanil
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Abnormal Menstrual Cycle
Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle
The study was done to evaluate the effects of the follicular and luteal phases of the menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50 during propofol anesthesia, in patients with and…
- Trial name
- NCT02035930
- Testing
- dexmedetomidine
- Volunteers
- 110 people
- Sponsor
- Fudan University
Anesthetics
A Comparative Study of Depth of Anesthesia Monitored by Bispectral Index (BIS) Values
The aim of this study is to determine whether induction of anesthesia with thiopental followed by propofol infusion is able to maintain sufficient depth of anesthesia .
- Trial name
- NCT01140100
- Testing
- propofol, thiopental,propofol
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Shiraz University of Medical Sciences
Atrial Fibrillation, Electric Countershock
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart.
- Conditions
- Atrial Fibrillation, Electric Countershock, Deep Sedation
- Trial name
- BIS-ECV-RCT (NCT07569016)
- Testing
- BIS-guided propofol sedation, Clinical-guided propofol sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Deep Hypnotic Time, Emergence Time
Comparison of DHT Duration in Geriatric Patients Using BIS Monitoring
Without adequate monitoring, administration of anesthetic agents can create unnecessary deeper anesthetic plane in geriatric population.
- Conditions
- Deep Hypnotic Time, Emergence Time, Geriatric Population, General Anesthesia
- Trial name
- NCT06394362
- Testing
- Bispectral index monitor
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anaesthesia
Dexmedetomidine-propofol-remifentanil Anaesthesia and Reactivity to Noxious Stimuli
Dexmedetomidine acts at central nervous system (specifically: at locus caeruleus), providing sedative and analgesic effects. It is widely used in intensive care.
- Trial name
- NCT01076790
- Testing
- Dexmedetomidine, Saline
- Where
- Finland
- Volunteers
- 44 people
- Sponsor
- Arvi Yli-Hankala
Explicit Recall of Intra-Operative Events
Study Evaluating Whether the Bispectral Index Prevents Patients at Higher Risk From Being Awake During Surgery and Anesthesia
The overall purpose of this study is to see if a Bispectral Index (BIS) monitor, a Food and Drug Administration (FDA) approved brain monitoring device, will help to reduce the risk of patients remembering being awake during…
- Trial name
- BAG-RECALL (NCT00682825)
- Testing
- Bispectral index protocol, End tidal anesthetic gas-guided
- Where
- 3 sites in United States, Canada
- Volunteers
- 6,000 people
- Sponsor
- Washington University School of Medicine
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Music and Anesthesia
The Effects of Instrumental Music on Intraoperative Parameters and Postoperative Pain and Side Effects
The clinical study started after receiving ethical approval from the Clinical Research Ethics Committee of Van Yüzüncü Yıl University and obtaining patient consent.
- Trial name
- NCT05886231
- Testing
- music sound therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Brain Injury
Combining Observational and Physiologic Sedation Assessment Tools
When a physiologic tool to measure the patient's hypnotic state is added to current practice tools is there a decrease in the amount of drug the patient receives.
- Trial name
- COST (NCT00538369)
- Testing
- Ramsay Scale, Bispectral index monitor
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Duke University
Sleep Quality
Infant Swing and Sleep-Wake Cycles
This study was planned to determine the effects of automatic baby swing application on the sleep-wake cycle, comfort behaviors and physiological parameters of babies in the neonatal intensive care unit.
- Trial name
- AISS (NCT07284303)
- Testing
- Care: Automatic Baby Swing
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Loss of Consciousness
Sufentanil Bispectral Index Elderly
We compared BIS values during propofol stepwise induction with or without concomitant sufentanil in patients ≥ 65 years .
- Trial name
- NCT02831101
- Testing
- Sufentanil
- Volunteers
- 71 people
- Sponsor
- University Hospital, Geneva
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block and EEG Dynamics in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a commonly performed minimally invasive surgical procedure. Despite its minimally invasive nature, surgical stimulation and pneumoperitoneum may cause pain-related physiological and…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Intraoperative Nociception
- Trial name
- NCT07818954
- Testing
- Remifentanil, Ultrasound-Guided Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Respiration, Artificial
Effect of Bispectral Index (BIS) Titrated Propofol Sedation on Lower Esophageal Sphincter Pressures and Esophageal Function in Intensive Care Patients
Eligible patients will be allocated to receive propofol sedation titrated to 3 different Bispectral Index (BIS) levels in a random order.
- Trial name
- NCT01173263
- Testing
- BIS 70 maintained, BIS level 50, BIS 35
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Cleveland Clinic
Traumatic Brain Injury
Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients
This study was conducted in two parts: 1. This first part was designed to determine thiopentone dose requirement for induction of anaesthesia with and without the use of Bispectral Index monitoring - Participant and Care Provider…
- Trial name
- NCT03480880
- Testing
- Bispectral Index
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Anesthesia
Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
A correlation between the bispectral index values and electroencephalographic patterns at the loss of consciousness (LOC) when using propofol in elderly patients, has not been determined.
- Trial name
- NCT03195530
- Testing
- Propofol
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Oxidative Stress
Does the Use of Bispectral Index Reduce the Oxidative Stress in Endoscopic Retrograde Cholangiopancreatography?
Objective Endoscopic Retrograde Cholangiopancreatography (ERCP) is performed for resolving cholestasis by sphincterotomy and/or stone extraction and is done with deep sedation or general anesthesia.
- Trial name
- NCT02792751
- Testing
- Bispectral Index Monitorisation (BIS), Ramsey Sedation Scale
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Intravenous Access, Pediatric Patient
Intravenous Access Time in Pediatric Patients
In pediatric patients with no vascular access, anesthesia induction is usually achieved with sevoflurane. The aim of investigators to evaluate the optimum intravenous access time and the corresponding bispectral index (BIS) value…
- Trial name
- NCT04190407
- Testing
- Intravenous access
- Volunteers
- 84 people
- Sponsor
- Istanbul Medeniyet University