Clinical trials: Bispectral Index
Anesthesia
Bispectral Index (BIS) Monitoring in Abdominal Surgery
Bispectral Index Monitoring (BIS) has been proven to be effective in preventing awareness. Optimizing anesthesia level using BIS monitoring, neither to light nor to deep will probably help to shorten recovery time and reduce drug…
- Trial name
- NCT01470898
- Testing
- bispectral index monitoring
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Dubrava
General Anesthesia, Intraoperative Monitoring
Equivalent MAC in General Anesthesia
This observational study aims to evaluate the clinical applicability of the Equivalent Minimum Alveolar Concentration (eMAC) parameter during general anesthesia.
- Conditions
- General Anesthesia, Intraoperative Monitoring, Anesthetic Depth
- Trial name
- NCT07197567
- Testing
- Sevoflurane + Remifentanil, Sevoflurane + Propofol + Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
General Anesthesia, Propofol Pharmacodynamics
Neuronal Inertia in Propofol Anesthesia
Loss and recovery of consciousness during propofol anesthesia seem to be mediated by different mechanisms beyond the actual effect-site concentration of anesthetic drug.
- Conditions
- General Anesthesia, Propofol Pharmacodynamics, Propofol Target Controlled Infusion, Loss of Consciousness and Recovery of Consciousness
- Trial name
- INERTIA (NCT01962285)
- Testing
- propofol targel controlled infusion
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Liver Transplantation
Closed-loop Anesthesia, Using Bispectral Index as the Control Variable, During Liver Transplantation
To compare closed-loop anesthesia to manual administration of propofol and remifentanil during liver transplantation
- Trial name
- Drone-TH (NCT00477347)
- Testing
- Closed loop administration, Manual administration
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Hopital Foch
Total Intravenous Anesthesia, Propofol
Total Intravenous Anesthesia With Remifentanil-propofol Admixture
Background: Application of total intravenous anesthesia (TIVA) may be considered as unpractical when compared with inhalational anesthesia.
- Conditions
- Total Intravenous Anesthesia, Propofol, Remifentanil, Bispectral Index Monitoring
- Trial name
- NCT04394897
- Testing
- Remifentanil-Propofol admixture
- Volunteers
- 96 people
- Sponsor
- Bezmialem Vakif University
Thyroid Disease
The Effective Blood Concentration of Ciprofol
1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3.
- Trial name
- NCT07294989
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Peking University Shenzhen Hospital
Depression
Investigation on the Value of Bilateral Index (BIS) Monitoring for Magnetic Seizure Versus Electroconvulsive Therapy
Electroconvulsive therapy (ECT) has been shown to be an effective treatment for patients suffering from depression, who do not respond to medical treatment.
- Trial name
- NCT01318018
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bonn
Anaesthesia
"Light" Versus "Deep" Bispectral Index (BIS) Guided Sedation for Colonoscopy
In this trial, patients undergoing elective colonoscopy under sedation will be randomised to BIS-guided sedation targeting either "light" (bispectral index [BIS] 70-80) or "deep" (BIS<60) sedation.
- Trial name
- NCT01457274
- Testing
- Sedation depth
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Melbourne Health
Surgical Procedure, Unspecified
Sugammadex: Effect on the Awareness Monitoring and Hemodynamics
Sugammadex is used to reverse the neuromuscular blocking effect of steroid neuromuscular blockers. Its cardiovascular effects and effect on brain cortex, if any, may be associated to the reversal of the neuromuscular block.
- Trial name
- NCT01301261
- Testing
- sugammadex, Sugammadex 4 mg/kg, Sugammadex 16mg/kg
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Athens
Cardiovascular Disease
Remifentanil Anesthesia and Postoperative BIS in Cardiac Surgery
Background: Although remifentanil based anesthesia has been preferred for fast-track cardiac anesthesia, its recovery profile in cognitive function has not been investigated.
- Trial name
- NCT02400879
- Testing
- Remifentanil, sevoflurane and sufentanil
- Volunteers
- 38 people
- Sponsor
- Konkuk University Medical Center
Anesthesia, General, Anesthesia, Intravenous
Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the…
- Trial name
- NCT02492282
- Testing
- Closed-Loop propofol and remifentanil system by Bispectral Index, Open-Loop propofol and remifentanil by Target Controlled Infusion, propofol
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Deep Hypnotic Time, Emergence Time
Comparison of DHT Duration in Geriatric Patients Using BIS Monitoring
Without adequate monitoring, administration of anesthetic agents can create unnecessary deeper anesthetic plane in geriatric population.
- Conditions
- Deep Hypnotic Time, Emergence Time, Geriatric Population, General Anesthesia
- Trial name
- NCT06394362
- Testing
- Bispectral index monitor
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia