Clinical trials: Bladder Voiding Dysfunction
Urinary Retention, Neurogenic Bladder
Connected Catheter- Safety and Effectiveness Study
The Connected Catheter is a fully internal, urethral indwelling urinary prosthesis designed for improved bladder management in males with urinary retention disorders requiring catheterization.
- Conditions
- Urinary Retention, Neurogenic Bladder, Urologic Diseases
- Trial name
- NCT03843073
- Testing
- Connected Urinary Catheter
- Where
- 9 sites in United States
- Volunteers
- 9 people
- Sponsor
- Spinal Singularity
Urinary Bladder Neoplasms, Sexual Dysfunction, Physiological
Sexual Function in Patients Suspected of Non-muscle Invasive Bladder Cancer
The purpose of the study is to investigate sexual function in patients suspected of non muscle invasive bladder cancer (NMIBC). The investigators hypothesis is that reduced sexual function is underdiagnosed in patients with…
- Conditions
- Urinary Bladder Neoplasms, Sexual Dysfunction, Physiological, Sexual Dysfunctions, Psychological, Erectile Dysfunction
- Trial name
- NCT02381912
- Testing
- EORTC QLQ-C30 and EORTC BLS-24 questionnaire
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Herlev Hospital
Bladder Voiding Dysfunction
User Satisfaction When Catheterizing With Hydrophilic Urinary Catheters From a More Sustainable Manufacturing Process.
An open, prospective, single arm, multicenter clinical investigation. All subjects will use the investigational device for 30 days each.
- Trial name
- NCT04703413
- Testing
- LoFric® OrigoTM and LoFric® SenseTM
- Where
- 3 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Wellspect HealthCare
Pelvic Floor Disorders, Sexual Dysfunction
A Long-term Evaluation of a Novel Intravaginal Device
An open-label long-term evaluation of a novel intravaginal device in female patients experiencing sexual and bladder function issues.
- Conditions
- Pelvic Floor Disorders, Sexual Dysfunction, Stress Incontinence
- Trial name
- NCT03073824
- Testing
- vSculpt
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Joylux, Inc.
Dysfunctional Voiding, Bladder Dysfunction
Linguistic Validation of the Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ) for 5-12 Years Old in Korean
The study is to conduct a linguistic and cultural validation of the Children Bladder and Bowel Dysfunction (CBBDQs) for 5-12 years old from English to Korean.
- Conditions
- Dysfunctional Voiding, Bladder Dysfunction, Bowel Dysfunction, Pediatric Urology
- Trial name
- NCT04490642
- Testing
- Questionnaire
- Where
- 3 sites in South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Voiding Disorders, Overactive Bladder
Beta 3 Agonists in Treatment of Non-neurogenic Voiding Dysfunction in Children
A randomized clinical study to evaluate the safety and efficacy of using the Beta 3 agonist drug (Mirabegron) combined with standard behavioral therapy in comparison to using the anticholinergic drug (Solifenacin) combined with…
- Trial name
- NCT05240456
- Testing
- Beta3-Agonists, Adrenergic, Anticholinergic drug, Solifenacin
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Multiple Sclerosis, Anorectal Disorders
Effect of Need to Void on Rectal Sensory Function in Multiple Sclerosis
Multiple sclerosis causes demyelinating lesions, which can induce multiple symptoms. Ano-rectal avec urinary disorders are frequent due to specific lesions in inhibitor/activator encephalic centers, or interruption on medullary…
- Conditions
- Multiple Sclerosis, Anorectal Disorders, Bladder Dysfunction
- Trial name
- NCT04057222
- Testing
- No intervention
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Gérard Amarenco
Voiding Dysfunction
Randomized Controlled Trial of Cystocele Plication Risks ("CPR Trial"): A Pilot Study
Up to 50% of patients undergoing pelvic floor repair experience short-term postoperative voiding dysfunction, increasing the length of hospitalization, cost and anxiety among patients.
- Trial name
- CPR (NCT01197248)
- Testing
- Cystocele plication, No Plication
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Urology, Urinary Bladder, Overactive
Ambulatory Long Length URodynamics Evaluation
A prospective, open-label, single arm interventional trial evaluating the safety and performance of the in-clinic and extended monitoring of the lower urinary tract using the Glean Urodynamics System.
- Conditions
- Urology, Urinary Bladder, Overactive, Benign Prostatic Hyperplasia, Urodynamics
- Trial name
- ALLURE (NCT07425015)
- Testing
- Glean Urodynamics System
- Where
- 9 sites in United States
- Volunteers
- 101 people
- Sponsor
- Bright Uro
Overactive Bladder, Voiding Disorders
Feasibility of Parasacral Transcutaneous Electrical Nerve Stimulation PTENS for Voiding Dysfunction in Peds Population
Pilot study for determining feasibility of home parasacral transcutaneous electrical nerve stimulation in treatment of urinary urgency and incontinence.
- Conditions
- Overactive Bladder, Voiding Disorders, Incontinence, Urinary
- Trial name
- NCT04570605
- Testing
- parasacral transcutaneous electrical nerve stimulation (PTENS), Standard Urotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Myelomeningocele, Neurogenic Bladder
Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
- Conditions
- Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic
- Trial name
- NCT04738539
- Testing
- Contrast Enhanced Voiding Urosonography with Urodynamic Testing, Urodynamic Testing
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic
Efficacy and Tolerability of Propiverine Hydrochloride in Patients With Neurogenic Detrusor Overactivity
The purpose of this clinical study is to compare efficacy and safety of propiverine hydrochloride extended and immediate release formulations in patients suffering from neurogenic detrusor overactivity.
- Conditions
- Neurogenic Urinary Bladder Disorder, Urinary Bladder, Neurogenic, Bladder Disorder, Neurogenic, Urinary Bladder Disorder, Neurogenic
- Trial name
- NCT01530620
- Testing
- Propiverine hydrochloride ER (extended release), Propiverine hydrochloride IR (immediate release)
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- APOGEPHA Arzneimittel GmbH
Voiding Dysfunction
Clinical Implication of DAC (Detrusor After-contraction)
The aims of this study are to confirm whether detrusor after-contraction (DAC) is a true contraction or not with a new approach and to understand clinical implication of DAC
- Trial name
- DAC (NCT01154946)
- Where
- South Korea
- Volunteers
- 2,309 people
- Sponsor
- Seoul National University Hospital
Voiding Disorders
Prevalence of Detrusor Underactivity and Bladder Outlet Obstruction in Female Without Cystocele
Women with symptoms of voiding dysfunction may be associated with detrusor underactivity (DU) or bladder outlet obstruction (BOO). The treatment strategies are different between DU and BOO.
- Trial name
- NCT04184752
- Testing
- Urodynamic study
- Where
- Taiwan
- Volunteers
- 602 people
- Sponsor
- National Taiwan University Hospital
Urinary Incontinence, Urinary Incontinence, Stress
Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women
Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence (UI), Urinary Bladder, Overactive
- Trial name
- SE-inc1 (NCT06933407)
- Testing
- Strain Elastography
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
Neurogenic Bladder Disorder, Non-Neurogenic Bladder
Define Final Selection Choice Criteria for a Coloplast Catheter Ensuring Highest Patient Satisfaction Via Surveys (EVA).
Understanding the Coloplast Intermittent Catheter Selection Study: This study aims to understand how adults who need to use catheters to empty their bladder by themselves decide which Coloplast catheter works best for them.
- Conditions
- Neurogenic Bladder Disorder, Non-Neurogenic Bladder, Bladder Dysfunction, Urinary Retention
- Trial name
- EVA (NCT07355803)
- Testing
- Questionnaires : Patient questionnaire on catheter use and satisfaction, IC-Di-Q, and I-CAT
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Coloplast NV/SA
Pelvic Organ Prolapse
Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse
This study will evaluate the effect of pessary therapy, with and without Solifenacin (Vesicare), on symptoms of over active bladder and bladder function in women with overactive bladder symptoms and pelvic organ prolapse.
- Trial name
- PESSARY (NCT01092624)
- Testing
- Solifenacin, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hartford Hospital
Overactive Bladder (OAB), Urgency Urinary Incontinence
Long-Term Effectiveness and Safety of Sacral Neuromodulation With InterStim for Lower Urinary Tract Dysfunction
This observational study will evaluate the long-term effectiveness, safety, and patient satisfaction associated with sacral neuromodulation using the InterStim™ system in adults treated for lower urinary tract dysfunction at…
- Conditions
- Overactive Bladder (OAB), Urgency Urinary Incontinence, Non-obstructive Urinary Retention, Non-obstructive Acontractile Detrusor
- Trial name
- NCT07856238
- Testing
- InterStim™ Sacral Neuromodulation System II - X
- Where
- Colombia
- Volunteers
- 1,700 people
- Sponsor
- Fundación Santa Fe de Bogota
Multiple Sclerosis, Bladder Dysfunction
Comparison of Craniosacral Therapy vs Pelvic Floor Physical Therapy
The purpose of this study is to determine the efficacy of CST for the treatment of LUTS in patients with MS and evaluate the acute effects compared to PFPT. A.
- Conditions
- Multiple Sclerosis, Bladder Dysfunction, Urinary Incontinence, Overactive Bladder
- Trial name
- NCT03213522
- Testing
- Pelvic Floor Physical Therapy, Craniosacral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CentraState Medical Center
Neurogenic Incontinence, Dysfunctional Voiding
Treatment of Neurogenic Incontinence by Surgery to Cut the Filum Terminale
The target population of this study is children with primary or secondary daytime urinary incontinence, who have failed to improve adequately despite compliance with at least 6 months of standard medical therapy.
- Trial name
- NICNOC (NCT01465581)
- Testing
- Division of the filum terminal
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nemours Children's Clinic