Clinical trials: Bleeding Complications
Central Venous Catheterization
Comparison of the Proximal Approach and Distal Approach of Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the proximal or distal approach of the axillary vein. The aim of our study is to compare the first puncture success rate and safety between the two approaches…
- Trial name
- NCT03395691
- Testing
- The distal approach, The proximal approach
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Shanghai Zhongshan Hospital
Cutaneous Vasculitis
IgA-positive Versus IgA-negative Immune Complex Vasculitis
Cutaneous vasculitis due to vascular deposition of large circulating immune complexes is a disease frequently seen by general practitioners and dermatologists.
- Trial name
- NCT01815190
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Gastric Variceal Bleeding
Comparison of Endoscopic Injection of Conventional and Double Doses Cyanoacrylate for Gastric Variceal Hemorrhage
The recent practice guideline recommends endoscopic injection of cyanoacrylate (GVO) is the preferred method to treat acute gastric variceal bleeding.
- Trial name
- NCT00735358
- Testing
- Cyanoacrylate
- Volunteers
- 105 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Preg Complications: Hemorrhagic, Infant, Premature, Diseases
Maternal & Infant Morbidity and Mortality
The purpose of this project is to evaluate maternal and infant outcomes based on race at UVA hospital. Health inequities are influenced by a combination of Social, Political, and Clinical determinants of health.
- Conditions
- Preg Complications: Hemorrhagic, Infant, Premature, Diseases, Preg Complications: Hemorrhagic Intervillous of Placenta, Preg Complications: Bleeding From Female Genital Tract
- Trial name
- NCT06145568
- Testing
- Pregnant Women
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Arthroplasty Complications, Total Knee Arthroplasty
Is Self-transfusion Safe After Total Knee Arthroplasty in Terms of Nephrotoxicity of Gentamicin From Bone Cement?
Considering that the high local concentration of antibiotic from bone cement is delivered intravenously through the self-transfusion process, systematic toxicity has never been evaluated.
- Trial name
- NCT04505748
- Testing
- Self-transfusion device
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University Hospital, Alexandroupolis
Postpartum Hemorrhage, Postpartum Women
Prevalence of Psychological Disorders After Immediate Postpartum Hemorrhage
The objective of this cross-sectional study is to assess the prevalence of depression at 2 months, 6 months, and 1 year postpartum in women who had an immediate postpartum hemorrhage (immediate PPH defined as blood loss ≥ 500 mL…
- Conditions
- Postpartum Hemorrhage, Postpartum Women, Postpartum Depression, Postpartum Stress
- Trial name
- PSYCHE (NCT03120208)
- Testing
- • The Edinburgh postnatal depression scale (EPDS), validated in French, with a discrimination threshold ≥ 11., The GAD-7 with a discrimination threshold ≥10., • Spielberger's State-Trait anxiety inventory, Form Y (validated in French), with a STAI (form Y-A) discrimination threshold ≥ 46
- Where
- France
- Volunteers
- 1,298 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intraventricular Hemorrhage, Premature Infants
Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome
Intraventricular hemorrhage and its resultant post-hemorrhagic hydrocephalus are significant risk factors for the development of neurodevelopmental delays in preterm infants.
- Trial name
- NCT00957840
- Testing
- NIRS, aEEG, and CSF concentration of biomarkers
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Utah
Blood Loss, Surgical
Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide Hemostatic System
This is a prospective, multicenter, multidisciplinary, controlled clinical investigation evaluating the safety and efficacy of PerClot in achieving intraoperative hemostasis compared to a similar marketed hemostatic device.
- Trial name
- CLOT (NCT02359994)
- Testing
- PerClot Polysaccharide Hemostatic System, Arista AH
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Artivion Inc.
Post Partum Hemorrhage
Oral Tranexamic Acid Plus Sublingual Misoprostol in Atonic Postpartum Hemorrhage
The aim of the study is to evaluate the effect of oral tranexamic acid plus, sublingual misoprostol in the management of atonic postpartum hemorrhage (PPH) after vaginal delivery
- Trial name
- NCT03870256
- Testing
- misoprostol, Carbetocin, TA
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Aswan University Hospital
Blood Loss, Surgical, Intrapartum Hemorrhage
Efficacy of Carbetocin Versus Oxytocin Plus Misoprostol in Decreasing Blood Loss During Cesarean Section
The aim of this clinical trial is to test if carbetocin is as effective as oxytocin plus misoprostol in decreasing intraoperative blood loss in women undergoing planned cesarean section.
- Trial name
- NCT05664659
- Testing
- Oxytocin + misoprostol, Carbetocin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams Maternity Hospital
Tracheal Intubation, Postoperative Complications (Cardiopulmonary)
Tracheal Cuff Pressure and Postoperative Complications
This prospective observational study aims to identify risk factors for tracheal mucosal injuries caused by orotracheal tube use during the intraoperative period in patients undergoing elective surgeries at the Hospital de…
- Trial name
- TCP-POC (NCT07264179)
- Where
- Brazil
- Volunteers
- 362 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postpartum Hemorrhage, Pregnancy
RCT of Misoprostol for Postpartum Hemorrhage in India
Death rates for pregnant women in rural India are approximately forty-five times higher than in the United States. Bleeding after the birth of a child and underlying anemia are the primary causes of mothers' deaths and sickness…
- Trial name
- NCT00097123
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Blood Loss, Surgical
B-lynch Transverse Compression Suture
Is B-Lynch transverse compression suture safe and effective in controlling excessive blood loss during conservative management of women with placenta previa?
- Trial name
- NCT06359886
- Testing
- B-Lynch Transverse Compression Suture
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Alexandria University
Complications; Cesarean Section, Adverse Reaction to Oxytocin
Outcomes After the Implementation of a New Oxytocin Protocol
The proposed study is a prospective, randomized, active control, open label study. One hundred sixty subjects undergoing elective cesarean section will be randomly assigned to one of two groups (n = 80 per group): the oxytocin…
- Trial name
- NCT02722356
- Testing
- Oxytocin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- C.R.Darnall Army Medical Center
Cancer, Tumour
Tranexamic Acid Versus Placebo for Blood to Reduce Perioperative Bleeding Post-liver Resection
Tranexamic acid (TXA) is an antifibrinolytic agent that has been shown to reduce blood loss and blood transfusion requirements in the following patient populations: multisystem trauma, liver transplantation, cardiac surgery and…
- Conditions
- Cancer, Tumour, Surgery
- Trial name
- NCT01651182
- Testing
- No tranexamic acid, Tranexamic Acid
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Menorrhagia, Metrorrhagia
Severity of Bleeding as a Predictor of Quality of Life (QoL) in Women With Heavy Menstrual Bleeding (HMB) Under Dydrogesterone Treatment
Dydrogesterone is a retroprogesterone with a molecular structure similar to natural progesterone. As a C-21 steroid, it has a high affinity for progesterone receptors, a low antigonadotropic activity and antiestrogenic activity…
- Trial name
- NCT01647360
- Where
- 20 sites in Pakistan
- Volunteers
- 210 people
- Sponsor
- Abbott
Biliary Obstruction, Complication of Treatment
Treatment of Postsphincterotomy Bleeding With a Novel Self-assembling Peptide Hemostatic Gel.
The aim of this observational study is to evaluate safety and efficacy of a novel self-assembling peptide hemostatic gel in reduction of bleeding after endoscopic sphincterotomy during ERCP (endoscopic retrograde…
- Trial name
- ERCPURA (NCT05886127)
- Testing
- A novel hemostatic agent (Purastat®)
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- General University Hospital, Prague
PPH - Postpartum Hemorrhage, Eclampsia
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics
The aim of this randomized study is to compare a live, trained simulated patient with a high-fidelity manikin in obstetric emergency team training using two standardized scenarios.
- Trial name
- NCT07857551
- Testing
- Trained, standardized patient, MamaAnne Patient Simulator
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postpartum Hemorrhage
Excellent BRASSS-V Drape™ Versus Indirect Measurement Protocol for Measurement of Postpartum Blood Loss
Postpartum hemorrhage is one of the most common causes of maternal mortality and serious maternal morbidity, especially in the developing world.
- Trial name
- NCT01885845
- Testing
- Excellent BRASSS-V Drape™., Indirect weight assesment of blood loss
- Where
- India
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pancreatectomy, Complication of Surgical Procedure
Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty
To assess the efficacy of complete covering using retromesenteric omentoplasty vs. partial covering or no covering of peripancreatic arteries in decreasing incidence of grade B+C post-pancreatectomy hemorrhage (PPH), i.e.
- Trial name
- PACOMARCO (NCT05992857)
- Testing
- Pancreaticoduodenectomy without retromesenteric omental flap, Pancreaticoduodenectomy with retromesenteric omental flap
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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