Clinical trials: Bleeding Gastric
Gastroduodenal Ulcer
Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers
A randomized controlled trial to evaluate the efficacy of hemostatic forceps and bipolar electrocautery probes in patient with high risk bleeding gastroduodenal ulcers.
- Trial name
- NCT06393907
- Testing
- Hemostatic Forceps, Bipolar Electrocautery Probes
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Mahidol University
Gastric Volume, Aspiration
Ultrasound Evaluation of Gastric Volume in Pediatric Patients Undergoing Adenotonsillectomy Surgery
Adenoidectomy and/or tonsillectomy are performed for many reasons such as recurrent tonsil and adenoid infections, sleep apnea, symptomatic adenotonsillar hypertrophy, halitosis, peritonsillar abscess, and it is one of the most…
- Conditions
- Gastric Volume, Aspiration, Nausea, Bleeding
- Trial name
- NCT05734937
- Testing
- gastric assessment of gastric volume
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peptic Ulcer
Natural History of Non-steroidal Anti-inflammatory Drug and Non-Helicobacter Pylori in Bleeding Peptic Ulcers
The aim of this study is to study the natural history of the ulcer healing while on proton pump inhibitors (PPI) and the ulcer recurrence without acid suppression therapy of Non-steroidal Anti-inflammatory Drugs (NSAID)…
- Trial name
- NCT00153712
- Where
- China
- Volunteers
- 391 people
- Sponsor
- Chinese University of Hong Kong
Early Gastric Cancer, Gastric Dysplasia
Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD?
Aspirin and/or clopidogrel users are increasing due to increased prevalence of cardiovascular or cerebrovascular disease with an aging society in Korea.
- Trial name
- NCT01621451
- Testing
- aspirin and/or clopidogrel
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Endoscopic Surgical Procedures
Endoscopic Hand Suturing in the Prevention of Gastrointestinal Bleeding After Gastric Endoscopic Submucosal Dissection.
Endoscopic hand-suturing (EHS) is a significant improvement in gastrointestinal advanced endoscopic procedures. Evidence supporting its effectiveness in clinical practice is limited due to its recent introduction and limited…
- Trial name
- NCT06779266
- Testing
- Suturing, Clipping, No closure
- Where
- Poland
- Volunteers
- 179 people
- Sponsor
- Jagiellonian University
Gastro Intestinal Bleeding
Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch
The purpose of this study to improve methods of monitoring and diagnosing gastrointestinal bleeding via the E4 wristband, a biosensor watch.
- Trial name
- NCT03874169
- Testing
- E4 wristband
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Gastrointestinal Bleeding, Stress Ulcers
Stress Ulcer Prophylaxis in the Intensive Care Unit
Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported.
- Trial name
- SUP-ICU (NCT02467621)
- Testing
- Pantoprazole, Saline (0.9%)
- Where
- 33 sites in Denmark, Finland and 4 more
- Volunteers
- 3,350 people
- Sponsor
- Dr. Morten Hylander Møller
Esophageal Varices
Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding
Carvedilol versus endoscopic band ligation for primary prophylaxis of oesophageal variceal bleeding in cirrhotic patients with arterial hypertension
- Trial name
- NCT04499898
- Testing
- Carvedilol, Endoscopic band ligation
- Where
- Egypt
- Volunteers
- 306 people
- Sponsor
- Sherief Abd-Elsalam
Acute Coronary Syndrome, Myocardial Infarction
Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
The purpose of the COGENT-1 clinical trial is to determine whether CGT-2168 (clopidogrel and omeprazole) compared to clopidogrel is safe and effective in reducing the incidence of gastrointestinal bleeding and symptomatic ulcer…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- COGENT-1 (NCT00557921)
- Testing
- CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin, Plavix (clopidogrel 75 mg) and aspirin
- Where
- 491 sites in United States, Australia and 14 more
- Volunteers
- 5,000 people
- Sponsor
- Cogentus Pharmaceuticals
Arteriovenous Malformation, Gastrointestinal Bleed
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
The purpose of the Case-Specific Health Care Professional (HCP) Clinical Survey for Concerto Versa™ Detachable Coils, also known as the Concerto Versa HCP Clinical Assessment, is to collect early clinical data from HCPs to assess…
- Conditions
- Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
- Trial name
- NCT07639853
- Testing
- Concerto Versa™ Detachable Coils
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medtronic Endovascular
Early Gastric Cancer or Gastric Adenoma
Full-time RDI for ESD: Impact on Major Adverse Events and Procedure Time
Gastric cancer remains a major global health burden, ranking fifth in incidence worldwide and disproportionately affecting Asia, with China accounting for a significant share of cases and deaths.
- Trial name
- NCT07401303
- Testing
- ESD
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Congenital Heart Disease, Upper Gastrointestinal Bleeding
Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease
Infants with congenital heart disease often require an intervention during their first year of life. Infants are generally admitted to a cardiac intensive care unit and are routinely prescribed stress ulcer prophylaxis to…
- Conditions
- Congenital Heart Disease, Upper Gastrointestinal Bleeding, Stress Ulcer, Infection
- Trial name
- SUPPRESS-CHD (NCT03667703)
- Testing
- Famotidine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Peptic Ulcers
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer
The present study will compare the hemostasis-maintaining effects of intravenous omeprazole and ranitidine in patients with upper gastrointestinal hemorrhage that have undergone endoscopic hemostasis, to establish which…
- Trial name
- NCT00247130
- Testing
- Omeprazole, Ranitidine
- Where
- Japan
- Sponsor
- Keio University
Acute Variceal Bleeding
Clinical Characteristics Analysis and Prediction Model Establishment of Fatal Esophageal and Gastric Variceal Bleeding
The purpose of this study is to analyze the clinical characteristics of patients with fatal acute variceal bleeding (AVB) and establish a mortality risk prediction model to identify patients at high risk of death after admission…
- Trial name
- NCT05613309
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Chronic Liver Disease, Cirrhosis
MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy
The purpose of this study is to determine the effect on the (carbon 13 labelled(13C)-Methacetin Breath Test (MBT) of i.v. propranolol, a non-selective beta blocker (NSBB) following initial administration and after chronic use of…
- Conditions
- Chronic Liver Disease, Cirrhosis, Esophageal Varices, Portal Hypertension
- Trial name
- NCT01851252
- Testing
- Methacetin (with Breath testing device)
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Meridian Bioscience, Inc.
Supraglottic Airway Efficiency, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
The most common adverse event in endoscopic procedures is hypoxia. Different airway devices have been investigated in the literature to prevent hypoxia.
- Conditions
- Supraglottic Airway Efficiency, Airway Complication of Anesthesia, Airway Aspiration, Complication of Anesthesia
- Trial name
- NCT05360810
- Testing
- Wei Nasal Jet Tube, Gastro Laryngeal Tube
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Bezmialem Vakif University
Pancreatic Cancer, Surgery--Complications
ERAS Protocol in Pancreaticoduodenectomy and Total Pancreatectomy
In the study, the enhanced recovery after surgery (ERAS) program is applied to total pancreatectomy (TP) and low-risk pancreaticoduodenectomy (PD) patients identified by a small number of acinar cells in the cut edge of the…
- Conditions
- Pancreatic Cancer, Surgery--Complications, Pancreatic Fistula, Delayed Gastric Emptying
- Trial name
- NCT03757455
- Testing
- ERAS protocol preoperative actions, ERAS protocol intraoperative actions, ERAS protocol postoperative actions
- Where
- Finland
- Volunteers
- 35 people
- Sponsor
- Tampere University Hospital
Gastrointestinal Hemorrhage
A Comparison of Gastric pH Control With High Dose Intravenous or Oral Esomeprazole
The investigators hypothesize that high dose esomeprazole 80mg given as a bolus, followed by 8mg/h would render gastric pH near neutral and that pH control with esomeprazole given in such a high dose either intravenous or orally…
- Trial name
- NCT00164788
- Testing
- Intravenous bolus injection of esomeprazole, Oral esomeprazole
- Where
- China
- Volunteers
- 7 people
- Sponsor
- Chinese University of Hong Kong
Gastro Intestinal Bleeding
Management of Digestive Haemorrhaging In CHRU of Brest During 2009 and 2014
Gastro intestinal (GI) bleeding is relatively frequent and may lead to intensive care unit admission. Although a restrictive strategy for red blood cell transfusion is supported by a large randomized controlled trial literature…
- Trial name
- HDréa (NCT03379285)
- Where
- France
- Volunteers
- 272 people
- Sponsor
- University Hospital, Brest
Liver Cirrhosis, Esophageal and Gastric Varices
Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails
To observe and access the Effects and safety of terlipressin or high dose somatostatin/octreotide when usual dose somatostatin/octreotide fail to achieve hemostasis in patients with acute variceal bleeding.
- Conditions
- Liver Cirrhosis, Esophageal and Gastric Varices, Hemorrhage
- Trial name
- CER:T (NCT02311608)
- Testing
- Terlipressin, Usual Dose Somatostatin/Octreotide, High Dose Somatostatin/Octreotide
- Where
- China
- Volunteers
- 1,320 people
- Sponsor
- Shanghai Zhongshan Hospital