Clinical trials: Bloating
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Healthy
A Randomized, Placebo Controlled Clinical Study to Assess the Effect of a Blend of Digestive Enzymes and Extracts on Bloating in Adults.
Randomized, Double-Blind, Placebo-Controlled, Single-Center Clinical Study, where participants will take the Daily Supplement, and record Daily Symptoms, two clinical visits where Hydrogen and Methane Breath Test (HMBT) will be…
- Trial name
- NCT07033000
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Irritable Bowel Syndrome
Effect of Probiotic Supplement in Alleviating Functional Gastrointestinal Symptoms
The purpose of this study is to analyse the effect of a probiotic supplement on functional intestinal symptoms among subjects diagnosed with irritable bowel syndrome (IBS).
- Trial name
- NCT01728610
- Testing
- Probiotic (Active high), Probiotic (Active low)
- Where
- 2 sites in Finland
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Danisco
Gastrointestinal Health, Immune Health
The Effects of a Novel Probiotic on Gastrointestinal Health in Generally Healthy Adults
The primary objective of this study is to investigate the effect of an oral probiotic (Bacillus sp. spore preparation) on abdominal bloating, flatulence, and burping in generally healthy adults.
- Conditions
- Gastrointestinal Health, Immune Health, Digestive Health
- Trial name
- NCT05595980
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
Premenstrual Syndrome, Menstrual Pain
A Clinical Study to Assess the Effect of a Dietary Supplement on Menstrual Cycle Symptoms
This is a single-group, virtual clinical trial evaluating the effects of a daily dietary supplement (DITTO Cycle Supplement) on menstrual cycle symptoms across three menstrual cycles.
- Trial name
- NCT07267728
- Testing
- DITTO Cycle Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muse Nutrition Ltd
Gastrointestinal Health, Immune Health
Effect of Bacillus Subtilis BS50 Supplementation on Gastrointestinal Symptoms in Healthy Adults
The primary objective of this study is to investigate the effect of a novel Bacillus subtilis spore preparation on abdominal bloating, flatulence, and burping in healthy adults.
- Conditions
- Gastrointestinal Health, Immune Health, Cardiovascular Health, Digestive Health
- Trial name
- NCT05004454
- Testing
- Bacillus subtilis BS50 spore preparation, Maltodextrin
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
Digestive Health, Abdominal Discomfort
Study to Investigate the Efficacy of a Digestive Health Dietary Supplement on Post-meal Bloating in Healthy Participants
The goal of this crossover clinical trial is to evaluate the efficacy and safety of Bloat Gummies on postprandial bloating and related gastrointestinal discomfort in healthy adults with recurrent bloating.
- Conditions
- Digestive Health, Abdominal Discomfort, Gas and Bloating
- Trial name
- NCT07516587
- Testing
- Bloat Gummies
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arrae
Microbiota
Effects of Resistant Potato Starch on the Gut Microbiota
This was a randomized, double-blind, three-arm, parallel group clinical trial, which assessed the shifts that occur in microbial populations after four weeks of supplementation with resistant potato starch (SolnulTM) at two…
- Trial name
- NCT05242913
- Testing
- Resistant Potato Starch
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MSP Starch Products Inc.
Chronic Constipation, Constipation
Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
The purpose of this study is to evaluate the efficacy and safety of linaclotide compared with placebo in patients with chronic constipation (CC) and prominent abdominal bloating.
- Trial name
- NCT01642914
- Testing
- Linaclotide 290 micrograms, Linaclotide 145 micrograms
- Where
- 151 sites in United States, Canada
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Bloating
A Study to Evaluate OPTI-BIOME™ Bacillus Subtilis MB40 on Abdominal Discomfort, Gas and Bloating in a Healthy Population
The purpose of this study is to investigate the effects of OPTI-BIOME™ (Bacillus subtilis MB40), a probiotic supplement, on bloating, gas and abdominal discomfort symptoms in otherwise healthy adults.
- Trial name
- NCT02950012
- Testing
- OPTI-BIOME™ Bacillus subtilis MB40
- Where
- 3 sites in United States, Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
Gastrointestinal Dysfunction
An Efficacy Trial in the Research Area of Gastrointestinal Health & Bloating
A randomized, double-blinded, placebo-controlled, parallel study, to evaluate the effect of 8-week supplementation of a traditionally fermented organic coconut milk kefir compared to placebo on gastrointestinal symptoms in…
- Trial name
- NCT05418127
- Testing
- Active
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Coconut Goodness Food Products Inc.
IBS - Irritable Bowel Syndrome
Study to Evaluate the Efficacy of Poppi Apple Cider Vinegar Prebiotic Soda to Improve Gut Health In Participants
This exploratory observational trial provides the opportunity to gather information on the effect of daily consumption of Poppi Apple Cider Vinegar Prebiotic Soda on gut health and digestion.
- Trial name
- NCT05418439
- Testing
- Drink Poppi Soda
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Drink Poppi
Gastrointestinal Discomfort, Bloating
Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women
This study looks at whether a daily probiotic supplement can help improve mild-to-moderate stomach and digestive symptoms, such as gas and bloating, in women who also experience symptoms commonly associated with hormonal…
- Trial name
- NCT07831317
- Testing
- Active: Multi-strain probiotic dietary supplement
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Daily Nouri
Healthy Subjects
Evaluation of the the Efficacy of a Digestive Health Supplement in Healthy Subjects
The objective of this study is to evaluate the efficacy of a digestive health supplement via waist circumference measurements, daily bowel habit and symptom logs, and self-perception questionnaires (SPQ) over 4 weeks.
- Trial name
- NCT06680219
- Testing
- Active comparator
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pharmanex
IBS (Irritable Bowel Syndrome), Bloating
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating
This study is a randomized, double-blind, placebo-controlled, within-individual crossover trial designed to assess the impact of regular use of a consumer-grade FODMAP-targeting digestive enzyme blend (FODZYME®) on…
- Conditions
- IBS (Irritable Bowel Syndrome), Bloating, Abdominal Pain, Gut Health
- Trial name
- NCT07591584
- Testing
- FODMAP-targeting digestive enzyme blend
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kiwi Health Inc
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Healthy
Efficacy of Dietary Supplement in Subjects With Acid Reflux and/or Abdominal Bloating/Distention and GI Symptoms
This study was a prospective randomized clinical study. There was interventional treatment for a total of 8 weeks including a 2-week washout period.
- Trial name
- NCT06808867
- Testing
- Dietary Supplement with Active Ingredient Blend
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Dyspepsia, Epigastric Fullness
Effect of Gingest on Symptoms of Dyspepsia
This is a randomised, double-blind, placebo controlled study on the effect of Gingest (ginger root extract) on symptoms of dyspepsia in 150 participants with mild to moderate dyspepsia.
- Conditions
- Dyspepsia, Epigastric Fullness, Bloating, Epigastric Pain
- Trial name
- NCT03548363
- Testing
- Gingest powdered extract obtained from Ginger rhizomes
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Poor Energy Levels, Poor Metabolism
A Clinical Trial to Evaluate the Effects of a Supplement on Supporting Signs of a Healthy Metabolism
This study evaluates the effects of Love Wellness Energize, a dietary supplement, on supporting signs of a healthy metabolism in women aged 25-45 who report poor energy levels, perception of poor metabolism, difficulty with…
- Conditions
- Poor Energy Levels, Poor Metabolism, Difficulty With Weight Management, Bloating
- Trial name
- NCT07765407
- Testing
- Love Wellness Energize
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness