Clinical trials: Block
Adult Patients, Total Knee Arthroplasty
Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty
Single femoral nerve blockade combined with patient-controlled intravenous analgesia are used for postoperative analgesia for patients after TKA in the hospital of the investigators.
- Conditions
- Adult Patients, Total Knee Arthroplasty, Epidural Analgesia, Femoral Nerve Block
- Trial name
- NCT03203967
- Testing
- Epidural morphine, Single femoral nerve block, Intravenous morphine analgesia
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University First Hospital
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health
Lung Diseases
Serratus Posterior Superior Interfascial Plane Block for Thoracoscopic Surgery
Regional techniques can be used for postoperative pain control following VATS. Ultrasound (US) guided serratus posterior superior block (SPSPB) is a new interfacial plane block defined by Tulgar et al in 2023.
- Trial name
- NCT05972122
- Testing
- Analgesia management; group S and C
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Acute Ischemic Stroke
Thrombectomy Revascularization of Intracranial Vessel OcclusioN by Originating From Japan (TRON1-Japan)
To evaluate the efficacy and safety of catheter-based thrombectomy for reperfusion by removing a thrombus in a cerebral blood vessel in patients with acute cerebral infarction (within 8 hours after onset), in whom intravenous…
- Trial name
- TRON1-Japan (NCT02964702)
- Testing
- Thrombectomy Device T-01
- Where
- 13 sites in Japan
- Volunteers
- 50 people
- Sponsor
- JIMRO Co., Ltd.
Class II Division 2 Malocclusion
TMJ Adaptations by Orthodontic Treatment in Adolescent Females With Angle's Class II Division 2 Malocclusion: MRI Study
The aim of this study is to document the changes brought about in the internal anatomic relationships of the TMJ complex,positional changes of glenoid fossa with respect to adjacent cranial structures after completion of fixed…
- Trial name
- NCT04744337
- Testing
- orthodontic treatment
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Glioblastoma, Glioblastoma Multiforme (GBM)
The Effect of Glioblastoma PSMA Expression Following Tumour VEGF Blockade From Bevacizumab
This trial is a single arm study for patients receiving bevacizumab for IDH-wildtype glioblastoma. Patients receiving bevacizumab (an anti-VEGF therapy) will receive PSMA scans to investigate the role of PSMA expression in…
- Trial name
- GUAVA (NCT07052877)
- Testing
- PSMA PET/CT scan
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Royal North Shore Hospital
Paralytic Ileus
Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy
A multicenter randomized-controlled trial of daikenchuto (TJ-100), a traditional Japanese herbal medicine (Kampo), to investigate its effect on intestinal dysmotility and for the prevention of postoperative paralytic ileus.
- Trial name
- JAPAN-PD (NCT01607307)
- Testing
- Oral/enteral TJ-100 solution
- Where
- 5 sites in Japan
- Volunteers
- 220 people
- Sponsor
- Wakayama Medical University
Postoperative Pain
Comparison of Analgesic Effects of TAP Block and RSB in RALPs
In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.
- Trial name
- NCT06681571
- Testing
- TAP Block, RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Brachial Plexus Block
Supraclavicular Brachial Plexus Block During Upper Limb Surgeries
Comparative Study Between Ketamine-Bupivacaine Versus Bupivacaine With Intravenous Ketamine Infusion In Supraclavicular Brachial Plexus Block During Upper limb Surgeries The techniques of regional anesthesia have become very…
- Trial name
- NCT05315271
- Testing
- Bupivacaine-ketamine injection, Bupivacaine injection with intravenous ketamine infusion
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pediatric Patients, Congenital Heart Surgery
Pain Management of Pecto-intercostal Fascial Block Versus Intravenous Fentanyl After Pediatric Cardiac Surgery
Cardiac surgical patients often experience significant postoperative pain at the median sternotomy site. In pediatric cardiac surgery, the recommended pre bypass dose of fentanyl to blunt the hemodynamic and metabolic stress…
- Trial name
- NCT04945694
- Testing
- Ultrasound-guided bilateral pecto-intercostal fascial block, Intravenous fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA)
Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest
The aim of the study is to investigate whether occluding the abdominal aorta with an external device could be a potential therapeutic option in cases of non-traumatic cardiac arrest occurring outside of a hospital.
- Conditions
- Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA), Asystole, Pulseless Electrical Activity
- Trial name
- ATTICA (NCT07573566)
- Testing
- Abdominal Aortic Junction Tourniquet in non-traumatic out-of-hospital cardiac arrest
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Anesthesia Time
Single Lumen Intubation and Heart-Lung Machine (HLM) Mode Ventilation
In this trial, we aimed to compare anesthetic outcomes of single lumen intubation with Heart-Lung Machine mode ventilation versus double lumen intubation study in endoscopic thoracic sympathetic blockade.
- Trial name
- NCT05791045
- Testing
- single vs double
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Biruni University
Sinus-node Dysfunction
Right Ventricular Outflow Tract Study
This is a prospective, randomized, double blinded, multi-center, controlled study to evaluate the clinical impact at 18 months after DDD implantation of alternative pacing site (RVOTs and RVA) and the different conduction path…
- Trial name
- RVOTCARE (NCT01294839)
- Testing
- Right ventricular lead location
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Abbott Medical Devices
Supratentorial Brain Tumor Surgery
Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine
Cholinesterase inhibitors such as Neostigmine and Edrophonium have been used to reverse neuromuscular blockade after surgery. However, these drugs have a relatively slow onset and have adverse effects associated with stimulation…
- Trial name
- NCT02944175
- Testing
- Sugammadex, Neostigmine
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Aortic Valve Stenosis
Morbidity and Mortality Due to Deferral of Aortic Valve Replacement in Patients With Severe Aortic Stenosis
Background and Project Rationale: Degenerative aortic valve stenosis affects 2% of the elderly population aged 70 years or older and progresses insidiously with advancing age [1] before manifesting with symptoms such as decreased…
- Trial name
- AS DEFER (NCT04333875)
- Testing
- TAVR or SAVR
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Refractory Ventricular Tachycardia
Prospective Randomized Clinical Trial for Effect of Stellate Ganglion Block in Medically Refractory Ventricular Tachycardia
The investigators will compare the effects of PSGB(percutaneous stellate ganglion block) in patients with recurrent sustained VT/VF in spite of appropriate medical therapy and cardio-version/ defibrillation after correction of…
- Trial name
- NCT02646501
- Testing
- Antiarrhythmic drug, percutaneous stellate ganglion block (PSGB)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Coronary Artery Disease
LAAO With DAPT Versus Antithrombotic Therapy
This study will retrospectively review and compare clinical outcomes between left atrial appendage occlusion with dual antiplatelet therapy versus conventional antithrombotic therapy in patients with atrial fibrillation…
- Trial name
- NCT03310801
- Testing
- ACP or Watchman
- Volunteers
- 480 people
- Sponsor
- Korea University Anam Hospital
Upper Extremity Injury Trauma
Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block
The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block.
- Trial name
- NCT01334619
- Testing
- appropriate volume of 0.5% ropivacaine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Jishuitan Hospital
Asthma
Clinical Endpoint Trial Investigating Once Daily and Bronchodilator Dosing
Subjects will attend the unit for out-patient visits on Day 1, Day 7, Day 14 and Day 15 of each treatment period. The washout period between each treatment period will be a minimum of 10 days and maximum of 28 days.
- Trial name
- NCT00549744
- Testing
- GSK256066
- Where
- 3 sites in New Zealand, South Africa
- Volunteers
- 78 people
- Sponsor
- GlaxoSmithKline
Nerve Block
The MEV of 0.5% Ropivacaine in Ultrasound-guided SASIS-FICB
The Aim of This Study is to Determine the Minimum Effective Volume of Local Anesthetic (Ropivacaine 0.5%) Required to Produce an Effective Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment…
- Trial name
- SASIS-FICB (NCT05012137)
- Testing
- Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB) with 0.5% ropivacaine, different volume of 0.5% ropivacaine
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking Union Medical College Hospital