Clinical trials: Block Level
Pain, Postoperative
Pecs Block vs Local Infiltration in Mastectomy
Studied the comparison between PECS II block and LIA on pain intensity, opioid requirements, RNL, and postoperative IL-6 levels in MRM patients.
- Trial name
- PBLIM (NCT06451705)
- Testing
- PECS II block, LIA
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Trigger Finger, Stenosing Tenosynovitis
Low-Level Laser Therapy in the Treatment of Trigger Finger
Trigger finger, also known as stenosing tenosynovitis, is one of the most common disorders affecting the hand. Its lifetime prevalence is 2-3%.
- Conditions
- Trigger Finger, Stenosing Tenosynovitis, Trigger Digit
- Trial name
- NCT07753460
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Dokuz Eylul University
Postoperative Pain Management, Lumbar Discectomy
Quadro-Iliac Plane Block Versus Wound Infiltration for Postoperative Pain After Single-Level Lumbar Discectomy
This prospective observational study aims to compare the effects of the Quadro-Iliac Plane Block (QIPB) and wound infiltration (WI) on postoperative acute pain in adult patients undergoing elective single-level lumbar discectomy.
- Conditions
- Postoperative Pain Management, Lumbar Discectomy, Regional Anaesthesia
- Trial name
- NCT07237945
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elif Sarikaya Ozel
Analgesia, Breast Cancer
Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
Our aim will be to compare the analgesic efficacy and safety of ketamine and magnesium sulphate as adjuvants to levobupivacaine in erector spinae plane block in modified radical mastectomy.
- Trial name
- NCT04275661
- Testing
- Ultrasound (US) bi-level erector spinae block, levobupivacaine, Ketamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post Surgical Pain
USFIB at the Inguinal Ligament for Total Hip Arthroplasty
Hip replacement surgery is one of the most common elective surgeries in Canada and with this surgery, there is considerable pain after the operation.
- Trial name
- NCT01911949
- Testing
- Single shot femoral nerve block
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Aortic Valve Insufficiency, Aortic Valve Stenosis
Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery
General and specific objectives of the search: evaluate the effects of the administration of Antithrombin III (ATIII) on the activation of the coagulation system and of the fibrinolysis, platelet function, inflammatory response…
- Conditions
- Aortic Valve Insufficiency, Aortic Valve Stenosis, Mitral Valve Insufficiency, Mitral Valve Stenosis
- Trial name
- ATIII (NCT01201070)
- Testing
- antithrombin III
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Bari
Parasternal Block, Cardiac Surgery
Paraesternal Blockade and Lactate Serum Levels in Patients With Cardiac Surgery.
Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis.
- Conditions
- Parasternal Block, Cardiac Surgery, Serum Lactate
- Trial name
- NCT06608290
- Testing
- parasternal block, Lactate serum level
- Where
- Mexico
- Volunteers
- 86 people
- Sponsor
- Instituto Mexicano del Seguro Social
Analgesia
Erector Spinae Plane Block Versus General Anesthesia in Breast Cancer Surgeries
This study aims at comparing the analgesic efficacy and safety of bilevel erector spinae versus single level versus general anesthesia for breast cancer surgeries
- Trial name
- NCT05429489
- Testing
- Bilevel erector spinae plane block, Single level erector spinae plane block, Intravenous morphine
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Impact of Video-Based Patient Education on Physician Trust, Pain, and Anxiety in Laparoscopic Cholecystectomy
This prospective, randomized, single-center, single-blind study aims to evaluate the effects of video-based preoperative education on physician trust, postoperative pain, anxiety, and opioid consumption in patients undergoing…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy Surgery, Preoperative Anxiety, Trust in Healthcare System
- Trial name
- VITAP (NCT07767344)
- Testing
- Video-Based Preoperative Block Education, Standard Verbal Preoperative Block Education
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Sanliurfa Education and Research Hospital
Pain, Chronic
Great Occipital Nerve Block Using Different Approach
Great occipital nerve (GON) block is commonly applied for the pain management of occipital neuralgia, migraine, and cervicogenic headache.
- Trial name
- NCT06149299
- Testing
- Greater occipital nerve block
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Keimyung University Dongsan Medical Center
Target Controlled Infusion (TCI), Thoracic Epidural Anesthesia
The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction
It is a prospective, randomized, placebo-controlled study to investigate the effect of TEA with different block level on propofol concentration during general anesthesia induction.
- Conditions
- Target Controlled Infusion (TCI), Thoracic Epidural Anesthesia, Block Level, Gastrointestinal Surgery
- Trial name
- NCT02135016
- Testing
- 1% lidocaine, 2% lidocaine, 0.9% normal saline
- Where
- China
- Volunteers
- 45 people
- Sponsor
- First Hospital of China Medical University
Symptomatic First-degree Heart Block
Physiologic Pacing for Symptomatic First-Degree Heart Block
The purpose of this study is to determine if physiologic pacing will improve symptoms and outcomes in patients with symptomatic first-degree heart block (pr interval ≥250ms).
- Trial name
- NCT06245304
- Testing
- Dual chamber Medtronic pacemaker implantation., DDD-50 pacing program, AAI-DDD 50 pacing program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ascension Health
Severe Aortic Valve Stenosis, High-degree AV Block
Infranodal Conduction Time During TAVR as Predictor of HAVB
Consecutive patients with high grade aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) with a self-expanding valve (Medtronic CoreValve Evolut R® or Edwards Sapien S3®) without pre-existing pacemaker…
- Conditions
- Severe Aortic Valve Stenosis, High-degree AV Block, Left Bundle-Branch Block
- Trial name
- HOM-TAVI (NCT04128384)
- Testing
- Limited electrophysiologic study including measurements of HV- and AH-intervals pre- and post-TAVR
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Saarland
Prostate Cancer
Study on the Role of Hormonal Treatment for Two Dosage Levels of Prostate Radiation Therapy Versus Prostate Radiation Therapy Alone
The hypothesis of the proposed study would be that, due to the six months of total androgen blockade, which would include neoadjuvant hormonal therapy for four months and concomitant hormonal therapy for two months with…
- Trial name
- PCS III (NCT00223145)
- Testing
- Radiotherapy 70 Gy, Radiotherapy 76 Gy, Androgen blockade
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- Abdenour Nabid
Pain, Interscalene Blocks
Effect of Dexamethasone on Plasma Levels of Bupivacaine and Dexamethasone After a Single-injection Interscalene Nerve Block.
Recent studies have highlighted the comparative advantages of perineural dexamethasone, particularly regarding its safety profile and its ability to prolong analgesia in various peripheral nerve blocks.
- Conditions
- Pain, Interscalene Blocks, Dexamethasone, Bupivacaine
- Trial name
- NCT07324499
- Testing
- administration of dexamethasone intravenously
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain
Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block
Acute apical periodontitis (AAP) is an inflammatory condition of the periapical tissues of the periodontium, usually resulting from irreversible pulpitis and pulpal necrosis.
- Trial name
- NCT05479175
- Testing
- Ibuprofen, Diode laser, Nonactive Diode laser
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Mastectomy Patient
Bi-level Erector Spinae Plane Block and Pre-emptive Oral Tizanidine for Analgesia After Mastectomy Surgery
Effective management of postoperative pain in breast cancer surgery is essential to minimize the risk of developing postmastectomy pain syndrome.The aim of this study is to evaluate the effectiveness of combining bilevel erector…
- Trial name
- NCT07022353
- Testing
- Bilevel erector spinae plane block, tizanidine oral capsule
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Aortic Stenosis
Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis
One hundred patients with moderate to severe asymptomatic aortic stenosis (AS) will be asked to exercise on a treadmill. NT-pro-BNP levels will be drawn before and after exercise.
- Trial name
- AS-BNP (NCT00567437)
- Testing
- NT-pro-BNP levels
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Duke University