Clinical trials: Blockades Neuromuscular
Residual Neuromuscular Blockade, Curarization, Postoperative Residual
Validation of the REPS Prediction Tool
Neuromuscular blocking agents' (NMBA) use during surgery is associated with postoperative respiratory complications and increased risk of readmission to the hospital following ambulatory surgery.
- Conditions
- Residual Neuromuscular Blockade, Curarization, Postoperative Residual, Postoperative Respiratory Complication
- Trial name
- NCT03585400
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 101,510 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
7-dose Control - Progressive Muscle Relaxation Only, 5-dose - Pairs Progressive Muscle Relaxation With Fruit 5 Consecutive Days
Testing a Novel Stress-induced Eating Intervention for Cancer Prevention
Subjects will be enrolled in a stress-induced eating intervention with 5, 7, or 9 treatments or control. Treatment will comprise imagining a stressful event, engaging in a stress relief activity (Progressive Muscle Relaxation)…
- Conditions
- 7-dose Control - Progressive Muscle Relaxation Only, 5-dose - Pairs Progressive Muscle Relaxation With Fruit 5 Consecutive Days, 7-dose - Pairs Progressive Muscle Relaxation With Fruit 7 Consecutive Days, 9-dose - Pairs Progressive Muscle Relaxation With Fruit 9 Consecutive Days
- Trial name
- NCT03468257
- Testing
- Pavlovian Conditioning
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postoperative Residual Curarization, Neuromuscular Blockade
Infantile - Postoperative Residual Curarization - Study
The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.
- Conditions
- Postoperative Residual Curarization, Neuromuscular Blockade, Neuromuscular Monitoring
- Trial name
- I-PORC (NCT03804346)
- Testing
- Acceleromyography
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Magnesium Sulfate Causing Adverse Effects in Therapeutic Use, Neuromuscular Blockade
Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
It is well known that magnesium enhances the effect of neuromuscular blocking agents such as rocuronium. However, it is not known how much magnesium can reduce neuromuscular blocking agents in maintaining deep neuromuscular…
- Trial name
- NCT04013243
- Testing
- Magnesium Sulfate
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Caregiver Burden, Dementia
Progressive Muscle Relaxation Exercise on Care Burden, Depression, Anxiety, and Stress Levels in Dementia Caregivers
Dementia, which leads to deterioration in cognitive and behavioral functions, is a chronic progressive disease. Since the diagnosis is made, the care needs of the patients increase.
- Trial name
- NCT06143826
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Experimental Group 1 (Video Personal Expert), Experimental Group 2 (Video Factual Expert)
Do Videos That Aim to Optimize Expectations Alter the Effectivess of PMR?
The study's aim is to determine whether a short video aiming to optimize expectations regarding the effectiveness of progressive muscle relaxation (PMR) ist able to improve the actual effectiveness of PMR in comparison with a…
- Conditions
- Experimental Group 1 (Video Personal Expert), Experimental Group 2 (Video Factual Expert), Control Group
- Trial name
- NCT03330431
- Testing
- Progressive Muscle Relaxation (PMR)
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Neuromuscular Blockade
Acceleromyographic Assessment of Neuromuscular Blockade: TOF-Watch-SX Versus TOFscan
Muscle relaxants are administered to most patients undergoing general anesthesia in order to facilitate the placement of an endotracheal tube and improve operating conditions.
- Trial name
- NCT02433769
- Testing
- TOFscan, TOF-Watch-SX
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Stress Reaction, Stress, Psychological
Mind-Body Modalities for Nursing Students
Background: Nursing students around the world can experience tremendous stress due to their multi-faceted responsibilities. Stress is related to negative health and academic outcomes.
- Conditions
- Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT05172804
- Testing
- Progressive muscle relaxation, Guided Imagery, Mindfulness Meditation
- Where
- Jordan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Neuromuscular Blockade
Reversal of Neuromuscular Blockade During the General Anaesthesia
There are individual reports indicating that after the reversal of nondepolarizing neuromuscular blockade with neostigmine, some patients starts to relax spontaneously again after the tof ratio has already recovered to the safe…
- Trial name
- NCT04048655
- Testing
- Neostigmine, Combinations
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Critical Illness Polyneuropathy, Critical Illness Myopathy
Evaluation of the NeuroMuscular Junction Using the Single Fiber Electromyography and Reliability of Train-Of-Four in Critically Ill Patients.
Patients suffering from critical illnesses who are admitted to the Intensive Care Unit (ICU) are often affected by multiple organ failure.
- Conditions
- Critical Illness Polyneuropathy, Critical Illness Myopathy, Weakness Due to Disease, Neuromuscular Blockade
- Trial name
- NCT03893058
- Where
- Italy
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Pregnancy
Comparison of Onset and Duration of Rocuronium Between 2nd Trimester Pregnant and Non-pregnant Women
Pregnancy is associated with major changes of the body's physiological status and composition. These changes may modify the pharmacologic and/or pharmacokinetic profile of some drugs.
- Trial name
- NCT02797860
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Robot-Assisted Laparoscopic Radical Prostatectomy
The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged times of pneumoperitoneum.
- Trial name
- NCT02109133
- Testing
- deep neuromuscular blockade, moderate neuromuscular blockade, Rocuronium
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hypersensitivity, Anaphylaxis
A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)
The purpose of this study is to assess the potential for hypersensitivity symptoms upon repeat exposure to sugammadex. Healthy participants will be randomized to one of three treatment arms: sugammadex 4 mg/kg, sugammadex 16…
- Trial name
- NCT02028065
- Testing
- Sugammadex
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Musculoskeletal Pain, Neck Pain
AI-Assisted Camera-Based Progressive Muscle Relaxation for Office Workers
This randomized controlled trial evaluates the effectiveness of an AI-assisted, camera-based progressive muscle relaxation application in office workers aged 20 to 40 years.
- Conditions
- Musculoskeletal Pain, Neck Pain, Stress, Physiological, Work Related Musculoskeletal Disorders
- Trial name
- AI-PMR (NCT07571967)
- Testing
- AI-Assisted Camera-Based Progressive Muscle Relaxation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Neuromuscular Blockade
Effect of Dexamethasone on the Action of Sugammadex
This study aims to investigate the possible clinical effect of dexamethasone on the action of sugammadex when it is administered to reverse deep neuromuscular blockade caused by rocuronium in laparoscopic cholecystectomies.
- Trial name
- NCT02510157
- Testing
- Dexamethasone, Normal Saline, sugammadex
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Attikon Hospital
Neuromuscular Blockade
Effect of Magnesium Sulphate on Neostigmine
The purpose of this study is to evaluate the effect of magnesium sulphate on neostigmine-induced reversal of neuromuscular block by rocuronium
- Trial name
- NCT03020706
- Testing
- Magnesium Sulfate, Injectable
- Where
- South Korea
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Observation of Neuromuscular Block
Train of Four Motor Point Stimulation and Monitoring
The assessment of neuromuscular blockage is common practice in the operating room, in which such agents are employed. Still today, the use of simple hand held stimulators and visual monitoring of these responses are the norm.
- Trial name
- NCT02591108
- Testing
- Neuromuscular Block Aid, Standard of Care: Microstim Plus
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Vasomotor Symptoms, Hot Flashes
The Effect of Health Education and Progressive Muscle Relaxation Exercise on Vasomotor Symptoms and Sleep Problems With Perimenopausal Women
This study aims to determine the effect of health education and progressive muscle relaxation exercise (PMRE) on vasomotor symptoms and sleep problems in women with perimenopausal period; a randomized, pretest-posttest is a…
- Conditions
- Vasomotor Symptoms, Hot Flashes, Sleep Problem
- Trial name
- NCT04808232
- Testing
- progressive muscle relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sidika Pelit Aksu