Clinical trials: Blood
Cholesterol
Whey Protein Comparisons for Blood Lipid Effects
The goal of this clinical trial is to learn if hydrolyzed whey protein can help serum cholesterol stay in normal range in adults. As a side inquiry, a few blood measures will be taken that are relevant to low level inflammation.
- Trial name
- NCT07101263
- Testing
- Standard whey, Hydrolyzed whey
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medinutra LLC
Diagnostic Test
ABL90 FLEX PLUS Clinical Precision Study for 15 Parameters in Adult Whole Blood
Conducting the ABL90 FLEX PLUS Clinical Precision Study for 15 Parameters in Adult Whole Blood is to validate performance claims for precision in heparinized whole blood for 15 parameters: pH, pCO2, pO2, cCa2+, cCl-, cK+, cNa+…
- Trial name
- NCT05804487
- Testing
- ABL90 FLEX PLUS analyser running SW3.5 MR2.
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Radiometer Medical ApS
Biomarkers
Fruit and Vegetable Biomarker Discovery
The purpose of this research is to find a set of markers in the blood and/or urine that can be linked to consumption of specific fruits and vegetables.
- Trial name
- UCD-DBDC (NCT05621863)
- Testing
- Aim 1 Meal Challenge 1, Aim 1 Meal Challenge 2, Aim 1 Meal Challenge 3
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
HIV/AIDS
A Cluster Randomised Trial of Community-led Distribution of HIV Self-tests in Rural Malawi (HIV Self-Testing Africa [STAR])
The aim of this study is to determine the benefits, costs and safety of community-led delivery of HIV self-testing (HIVST) kits in rural Malawi, with a focus on testing and linkage to care and prevention services among defined…
- Trial name
- NCT03541382
- Testing
- OraQuick® HIV Self-Test
- Where
- Malawi
- Volunteers
- 7,880 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Human Immunodeficiency Virus
Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers
The investigators hypothesize that the concentration-time profile of raltegravir is different in cells than that in plasma. Intracellular raltegravir concentrations may be higher and its half-life longer than in plasma.
- Trial name
- NCT01027182
- Testing
- Raltegravir
- Where
- Singapore
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Hepatitis C
SPC3649 Multiple Dose Study in Healthy Volunteers
The purpose of this study is to investigate the safety and tolerability of SPC3649 given in multiple doses to healthy volunteers.
- Trial name
- NCT00979927
- Testing
- SPC3649, saline
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Santaris Pharma A/S
Cardiometabolic Risk Factors, Diabetes
Delta GREENS Food is Medicine Intervention
Mississippi is a place deeply rooted in cultural values, yet also a place where generations of communities have experienced persistent health challenges intertwined with poverty.
- Conditions
- Cardiometabolic Risk Factors, Diabetes, High Blood Pressure, Obesity
- Trial name
- NCT06358859
- Testing
- Food is Medicine
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tufts University
Myelodysplastic Syndromes
Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
Background: Myelodysplastic syndromes (MDS) are disorders of blood stem cells that can develop into blood cancers. Treatment options are limited. To find better treatments, researchers need to better understand how MDS develops.
- Trial name
- NCT05588154
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Asparagus Capsule Consumption
Asparagus Capsule Consumption and Blood Sugar and Lipids and Oxidative Stress
Participants were 44 overweight and obese persons, male and female, age 18-59 years. Participants were divided into 2 groups consisting of 23 asparagus capsules and 21 placebo capsules groups.
- Trial name
- NCT06195813
- Testing
- Asparagus capsule
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Burapha University
Emotional Processing, Mood
Combined Blood Pressure Medication and Activity Scheduling for Low Mood
This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood
- Trial name
- NCT07017023
- Testing
- Losartan with BA
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Sickle Cell Anemia, Blood Transfusion
Full Assessment of Clinical Transfusion Support
This study looks at why some children develop very severe anemia that leads to a blood transfusion. It also checks for diseases in the blood they receive.
- Conditions
- Sickle Cell Anemia, Blood Transfusion, Malaria Parasitaemia
- Trial name
- FACTS (NCT07094646)
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Blood Vessel Disease, Muscle Edema
The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs
The purpose of this study is to investigate the use of single (SC) and multi-chamber (MC) blood flow restriction (BFR) cuff exercise on indices of arterial stiffness, muscle morphology, and participant perception.
- Trial name
- NCT06276673
- Testing
- Delfi
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Salisbury University
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
RATIONALE: Giving chemotherapy and total-body irradiation (TBI) before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells and helps stop the patient's immune system from rejecting the donor's stem…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT01076270
- Testing
- plerixafor, filgrastim, peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
De Novo Autoimmune Hepatitis
De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
The purpose of this study is to provide insights into the cause, development and effects of de novo autoimmune hepatitis so that prevention and treatment strategies can be developed in order to reduce post-liver transplant…
- Trial name
- NCT02056054
- Testing
- Pediatric transplant subject with d-AIH, Pediatric transplant subject with acute rejection, Pediatric transplant subject with chronic rejection
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Yale University
Choroid, Retina
Effect of Different Wavelengths of Repeated Low-Level Light Therapy on Choroidal and Retinal Blood Flow Among Adults
The purpose of this clinical trial is to evaluate the effect of different intensity of repeated low-level red-light (RLRL) therapy on the choroidal and retinal blood flow among adults.
- Trial name
- NCT05796856
- Testing
- repeated low level light device (Eyerising [Suzhou Xuanjia Optoelectronics Technology)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Ichthyosis, Netherton Syndrome
Defining the Skin and Blood Biomarkers of Ichthyosis
Ichthyosis is a group of genetic skin disorders that present with dry, thickened, scaly, or flaky skin. As of today, there is no cure or treatment.
- Trial name
- NCT03417856
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Infections
Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically
Despite the widespread availability of effective antiretroviral therapy (ART) in the United States, there remains significant numbers of people living with HIV (PLWH) who fail to achieve and or maintain viral suppression (VS).
- Trial name
- EPI-LoVE (NCT06370780)
- Testing
- EPI LOVE
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy
A Study to Compare Capillary and Venous Whole Blood and Plasma Concentrations of Five Antipsychotics
The purpose of this study is to compare capillary (the smallest of a body's blood vessels) and venous whole blood and plasma concentrations of 5 antipsychotics after given of a single oral, immediate-release dose to healthy…
- Trial name
- NCT01607762
- Testing
- Aripiprazole, Quetiapine, Olanzapine
- Where
- Belgium
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
HIV Infections, Sexually Transmitted Disease
Effect of HIV/STD Risk Reduction Program on South African Adolescents
This study will evaluate the effect of an HIV/STD risk-reduction program on the sexual behavior of South African adolescents.
- Trial name
- NCT00559403
- Testing
- HIV/STD Risk-Reduction, Health Promotion
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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