Clinical trials: Blood
Multiple Myeloma, Cancer
Discontinuation Study
An interventional, non-randomised study to assess the risk of progression after discontinuation of maintenance therapy in sustained MRD negative complete remission by flow cytometry MM patients without high-risk features who have…
- Conditions
- Multiple Myeloma, Cancer, Hematologic Cancer
- Trial name
- NCT05866757
- Testing
- Discontinuation of maintenance treatment
- Where
- Ireland
- Volunteers
- 70 people
- Sponsor
- University College Cork
HIV Infections, Emphysema
Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center
Despite the availability of highly active antiretroviral therapy (HAART), lung diseases remain a leading cause of morbidity and mortality in those with HIV infection.
- Conditions
- HIV Infections, Emphysema, Chronic Obstructive Pulmonary Disease, Pneumocystis
- Trial name
- MACS (NCT00870857)
- Where
- 2 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Pittsburgh
Diabetes, Diabetes Mellitus, Type 2
Effects of Biphasic Insulin Aspart 70/30 vs. Exenatide in Type 2 Diabetes Patients Not Reaching Blood Glucose Targets on Metformin and a Sulfonylurea.
This trial is conducted in the United States of America (USA). The study will compare A1C reduction achieved in patients receiving biphasic insulin aspart 70/30 once or twice daily to patients receiving exenatide twice daily.
- Trial name
- NCT00313001
- Testing
- biphasic insulin aspart, exenatide
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Novo Nordisk A/S
AMD
the Blood-Aqeous Barrier During Anti-Angiogenic Therapy in Exudative Age-Related Macular Degeneration
To evaluate the status of the blood-aqueous barrier by objectively measuring protein concentration in the aqueous humor using laser flare photometry (LFP) in patients with exudative age-related macular degeneration (AMD)…
- Trial name
- BABAMD (NCT07375901)
- Testing
- laser flare photometry before intravitreal injection
- Where
- Ukraine
- Volunteers
- 30 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
HIV Infections
An Imaging Trial of the Distribution of Topical Gel in the Human Vagina: Assessment of Bare Spots
This study will assess the distribution of a microbicidal gel in the vagina and confirm the presence of bare spots. MRIs will be done with and without the addition of the MRI contrast Gadolinium to the microbicide in order to…
- Trial name
- NCT00214812
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Biosyn
Prostate Hyperplasia
The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate
Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss…
- Trial name
- NCT04848181
- Testing
- cyproterone acetate, finasteride, no treatment received
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Hypertension
Improving Health Outcomes: Blood Pressure
This quality improvement project is focused on improving hypertension care delivery processes in ambulatory clinical practices, 5 in Illinois and 5 in Maryland for a total of 10 practice sites.The primary aim of this quality…
- Trial name
- IHO:BP (NCT02021981)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- American Medical Association
Driving, Intoxication
Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving
The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between patients on chronic opioid treatment and…
- Conditions
- Driving, Intoxication, Impairment, Alcohol Impaired Driving
- Trial name
- ALCDrive (NCT00559819)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
HIV Infections, HIV Seronegativity
HIV Incidence and Participation Retention in Pune, India
The purpose of this study is to ensure that the HIV Prevention Trials Unit (HPTU) in Pune will be able to enroll and retain participants for 2 upcoming HPTN clinical trials.
- Trial name
- NCT00028119
- Where
- India
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Intermittent Claudication, PAD
Treatment of Intermittent Claudication by G-CSF-mobilized PB-MNC
This study will investigate the efficacy of G-CSF mobilized mononuclear cell injection of patients with PAD who presented with intermittent claudication.
- Conditions
- Intermittent Claudication, PAD, Atherosclerotic Ischemic Disease
- Trial name
- NCT03683628
- Testing
- PB-MNC therapy, No PB-MNC therapy
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Atrial Fibrillation (AF)
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly.
- Trial name
- ROXI-ATLAS (NCT07175428)
- Testing
- REGN7508, REGN9933, Apixaban
- Where
- 89 sites in United States, Argentina and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Regeneron Pharmaceuticals
Male Circumcision, HIV Prevention
Cohort Field Study to Assess the Safety and Efficacy of the PrePex Device for Non-Surgical Circumcision When Performed by Nurses
A range of observational and epidemiological studies have shown that the lifetime risk of HIV infection can be reduced by 70% through male circumcision.
- Trial name
- NCT01434628
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Cholesterol, Hypercholesterolaemia
Efficacy of Lactobacillus Mucosae DPC6426 on Blood-lipids
Cardiovascular disease (CVD) is the leading cause of death and morbidity in the EU. Among the recommendations to avoid heart disease is the maintenance of normal blood cholesterol levels, by ingesting a cardioprotective diet and…
- Trial name
- NCT07519967
- Testing
- Lactobacillus mucosae DPC6426
- Where
- Ireland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University College Cork
Stress, Blood Pressure
Art for Hearts/Black Women's Hearts Paint Night
The purpose of this research study is to learn about different techniques that can be used to increase self-reflection, reduce stress, manage high blood pressure in Black women.
- Trial name
- NCT05252507
- Testing
- Paint Night
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cerebral Aneurysm
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing interventional cerebral aneurysm coiling procedure are enrolled in this prospective…
- Trial name
- NCT02700607
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 40 people
- Sponsor
- Konkuk University Medical Center
Hepatitis B, Vaccination
Assessing the Reliability of Self-Reported Hepatitis B Vaccination Status in Outpatients: Evaluation of Individuals Born in France and Consulting at the CeGIDD in Saint-Denis.
This study aims to find out whether people accurately know their hepatitis B vaccination status. It focuses on individuals born in France who visit a sexual health clinic (CeGIDD) in Saint-Denis.
- Conditions
- Hepatitis B, Vaccination, Health Knowledge, Attitudes, Practice, Serologic Tests
- Trial name
- NCT06998992
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Hypertension
Effectiveness of SMS Text Reminders to Improve Blood Pressure Among Patients With Hypertension
Objective: To test the primary hypothesis that SMS text messages delivered to patients via mobile phone can improve blood pressure within 12 weeks compared to usual care Design: Parallel group, randomized, controlled trial; the…
- Trial name
- NCT01255436
- Testing
- SMS text reminders, Usual Care
- Where
- Philippines
- Volunteers
- 700 people
- Sponsor
- University of the Philippines
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
BFR After Biceps Tendon Repair and MPFLR
The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy after distal biceps tendon repair or medial patellofemoral ligament reconstruction (MPFLR) following a tear.
- Trial name
- NCT05375071
- Testing
- Blood Flow Restriction (BFR) Therapy, Physical Therapy
- Where
- United States
- Sponsor
- Mayo Clinic
Obesity, Body Composition
Study of Macronutrients and Heart Disease Risk
The objective of this trial is to examine the long-term effects of a diet low in carbohydrates, as compared to one low in fat, on cardiovascular disease risk factors, including blood pressure (BP), body weight and composition…
- Conditions
- Obesity, Body Composition, Blood Pressure, Cardiovascular Diseases
- Trial name
- MACRO (NCT00609271)
- Testing
- low carbohydrate diet, low fat diet
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Tulane University Health Sciences Center
Immune Thrombocytopenia (ITP)
A Phase 1/2 Study of ESG206 in Patients With Primary Immune Thrombocytopenia
This is a multicenter, open-label Phase1/2 study aimed at evaluating the safety, tolerability, pharmacokinetic (PK) profile, pharmacodynamics (PD), immunogenicity, and preliminary efficacy of ESG206.
- Trial name
- NCT06853444
- Testing
- ESG206
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai Escugen Biotechnology Co., Ltd
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