Clinical trials: Blood Antibiotic Levels
Aortic Aneurysm and Dissection, Cardiac Valve Disease
Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients
According to the literature, presepsin was recommended not only as an effective indicator in the diagnosis of sepsis in intensive care units, but also as a reliable prognostic marker of postoperative inflammatory processes in…
- Conditions
- Aortic Aneurysm and Dissection, Cardiac Valve Disease, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
- Trial name
- NCT06336213
- Testing
- Ampicillin-sulbactam
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Idiopathic Infantile Hypercalcemia - Mild Form
The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH
Idiopathic infantile hypercalcemia(IIH) is a rare,genetic disorder of mineral metabolism. Biallelic loss of functions mutations of CYP24A1, the gene encoding the 24-hydroxylase enzyme that represents the principal pathway for…
- Trial name
- NCT03384121
- Testing
- Rifampin 150 mg, 300 mg capsules and 25 mg/mL oral suspension
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- The Hospital for Sick Children
Healthy
A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately
This is a randomised study divided into 2 parts. Part A investigates the effect of prolonged dosing (ten days) with Avibactam and Ceftazidime when given together and how this will effect how much Avibactam and Ceftazidime enters…
- Trial name
- NCT01430910
- Testing
- CAZ104, Avibactam, Ceftazidime
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pfizer
Administration of Antibiotics in Intensive Care Units
Antibiotic Concentrations Among Critically Ill Patients
The primary objective of the DALI study is to compare antibiotic concentrations in patient blood samples with bacteriological objectives associated with maximum bactericidal activity.
- Trial name
- DALI (NCT01543334)
- Testing
- Blood sampling
- Where
- 13 sites in France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Febrile Illness, Use of Antimicrobial Agents
Comparison of Rates of Antimicrobial Use in Febrile Patients With or Without the Use of C-reactive Protein Blood Test
In Health Posts of rural areas operated by the Government of Nepal, there are limitations of tests to differentiate between bacterial and viral infections.
- Conditions
- Acute Febrile Illness, Use of Antimicrobial Agents, C-reactive Protein Level
- Trial name
- CREATIB (NCT05292508)
- Testing
- C-reactive Protein Rapid Diagnostic Test
- Where
- Nepal
- Volunteers
- 924 people
- Sponsor
- Patan Academy of Health Sciences
Antibiotic, Anti-Bacterial Agents
Influence of Perioperative Fluid Balance on Serum Concentrations of Antibiotics and Surgical Site Infections
This study evaluates antibiotic serum concentrations in correlation with perioperative fluid balance. Patients will be recruited in rectum and esophageal surgery (representative for low blood loss and restrictive fluid…
- Conditions
- Antibiotic, Anti-Bacterial Agents, Surgical Wound Infection
- Trial name
- NCT03408457
- Testing
- Blood sampling after antibiotic administration
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Johannes Gutenberg University Mainz
Esophageal Achalasia
Bacteremia and Procalcitonin Levels in Peroral Endoscopic Myotomy for Achalasia
Peroral Endoscopic Myotomy (POEM) is a novel, promising endoscopic technique for achalasia because it is safer and more effective than traditional Heller's myotomy.
- Trial name
- NCT01750385
- Testing
- no antibiotic prophylaxis, second-generation cephalosporin
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Infections
Study of Blood Levels of Ceftaroline Fosamil in Children Who Are Receiving Antibiotic Therapy in the Hospital
The purpose of this study is to assess blood levels of Ceftaroline fosamil in children.
- Trial name
- NCT01298843
- Testing
- Ceftaroline fosamil
- Where
- 15 sites in United States
- Volunteers
- 53 people
- Sponsor
- Forest Laboratories
Bacterial Infections
Personalized Antibiotic Therapy - Point-of-Care Determination of Blood Levels of Beta-Lactam Antibiotics Using Coated-Blade-Spray Ion Mobility Spectrometry
A new analytical method for determining beta-lactam antibiotic concentrations in the blood of intensive care patients is to be evaluated.
- Trial name
- CBS-IMS (NCT07666230)
- Volunteers
- 200 people
- Sponsor
- Dr. T. Perl
Blood Antibiotic Levels
Preventive Antibiotic Serum Levels During Caesarean Section
Background Preventive antibiotic treatment before performing invasive procedures is a basic element in preventing infections. The essence of preventive antibiotic treatment is strengthening the defense mechanisms of the immune…
- Trial name
- NCT02838940
- Testing
- Blood samples., Cefazolin
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center