Clinical trials: Blood Clot
Thromboembolism
Thromboprophylaxis and Bariatric Surgery
This trial is an assessment of the efficacy of three thromboprophylaxis regimens in two types of bariatric surgery. gastric banding and gastric bypass on anti-Xa activity levels The study includes two groups of 150 patients…
- Trial name
- NCT00444652
- Testing
- Enoxaparin
- Where
- 10 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Deep Vein Thrombosis, Atrial Fibrillation
Clinical Pharmacist-led Inpatient Anticoagulation Stewardship Program
This study aims at evaluating the implementation of clinical-pharmacist-led anticoagulation stewardship program in Egyptian tertiary hospital to promote a culture of safety around anticoagulants.
- Conditions
- Deep Vein Thrombosis, Atrial Fibrillation, Mitral Valve Disease
- Trial name
- NCT03812848
- Testing
- Anticoagulation Stewardship Program
- Where
- Egypt
- Volunteers
- 233 people
- Sponsor
- Ain Shams University
Valvular Heart Disease Patients
Rivaroxaban vs Warfarin in Patients With Mechanical Heart Valves
Warfarin is the standard anticoagulant used for patients with mechanical heart valves; however, its use is complicated by a narrow therapeutic window, frequent drug and dietary interactions, and the need for regular international…
- Trial name
- NCT07456085
- Testing
- Rivoroxaban, Warfarin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Rawalpindi Institute of Cardiology
Glaucoma, New Onset Glaucoma
Lucentis for New Onset Neovascular Glaucoma
Neovascular glaucoma is a potentially debilitating disease of the eye. Vascular eye disease such as diabetes and vein occlusions can cause the retina to release factors that promote the growth of abnormal blood vessels.
- Conditions
- Glaucoma, New Onset Glaucoma, Neovascular Glaucoma, New Onset Neovascular Glaucoma
- Trial name
- NVG (NCT00727038)
- Testing
- Ranibizumab (Lucentis)
- Sponsor
- University of Illinois Chicago
Venous Thromboembolism, Hemorrhage
A Clinical Cohort Study of Safety and Effectiveness of Venous Thromboembolism Prophylaxis in Critical Ill Patients
The purpose of this study is to analyze the effect of the prophylaxis of venous thromboembolism in the critical ill patients, and at the same time, to find out the risk of venous thromboembolism and hemorrhage events occurred…
- Trial name
- VTEH (NCT02213978)
- Where
- China
- Volunteers
- 1,114 people
- Sponsor
- Beijing Chao Yang Hospital
Neoplasm, Venous Thromboembolism
Cancer Associated Thrombosis, a Pilot Treatment Study Using Rivaroxaban
The study will compare the efficacy and safety of oral rivaroxaban and subcutaneous dalteparin in patients with cancer associated thrombosis.
- Trial name
- CASTA-DIVA (NCT02746185)
- Testing
- rivaroxaban, Low-molecular-weight heparin
- Where
- 15 sites in France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Left-sided Prosthetic Heart Valve Thrombosis
Surgery Versus Fibrinolytic Therapy for Left-sided Prosthetic Heart Valve Thrombosis
Malfunction of mechanical heart valves due to clot formation is a potentially devastating complication. It often results in heart failure, death or stroke.
- Trial name
- SAFE-PVT (NCT01641549)
- Testing
- Emergency surgery, Fibrinolytic therapy
- Where
- India
- Volunteers
- 115 people
- Sponsor
- All India Institute of Medical Sciences
Thromboembolism
A Study to Compare Health Care Costs Between Apixaban and Low Molecular Weight Heparin in Patients With Venous Thromboembolism and Cancer
The purpose of this study is to evaluate the health care resource utilization and costs associated with treating patients diagnosed with cancer and venous thromboembolism with apixaban or low molecular weight heparin.
- Trial name
- NCT05643885
- Where
- United States
- Volunteers
- 7,304 people
- Sponsor
- Pfizer
Prevention of Arterial and Venous Thrombosis
A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
The purpose of the study is to evaluate the efficacy and safety of SHR-2004 in preventing venous thromboembolism after elective unilateral total knee arthroplasty.
- Trial name
- NCT06825416
- Testing
- SHR-2004 injection, Enoxaparin sodium injection
- Where
- 2 sites in China
- Volunteers
- 1,165 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Acute Myocardial Infarction, STEMI
Multi-modality Imaging in Acute Myocardial Infarction
The goal of this study is to use three (3) different imaging techniques:Fractional Flow Reserve (FFR) allows precise measurement of blood flow in the arteries to the heart, and is more reliable than pictures alone to determine…
- Conditions
- Acute Myocardial Infarction, STEMI, Coronary Artery Disease, Atherosclerotic Plaque Disruption With Thrombosis of Artery
- Trial name
- MIAMI (NCT02926755)
- Testing
- Coronary Angiography
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Corewell Health East
Ischemic Stroke, Large Vessel Occlusion
Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
Background: Intravenous thrombolysis (IVT) combined with mechanical thrombectomy (MT) has been proven safe and effective in patients with acute ischemic stroke (AIS) of anterior circulation large vessel occlusion (LVO).
- Conditions
- Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- DIRECT-MT (NCT03469206)
- Testing
- intra-arterial thrombectomy, Intravenous thrombolysis
- Where
- China
- Volunteers
- 656 people
- Sponsor
- Changhai Hospital
Cerebral Venous Thrombosis
Direct Oral Anticoagulants for the Treatment of Cerebral Venous Thrombosis
Rationale: Patients with cerebral venous thrombosis (CVT) are currently treated with anticoagulants during 3-12 months after diagnosis, to prevent worsening of the CVT and recurrent thrombosis, and to promote venous…
- Trial name
- DOAC-CVT (NCT04660747)
- Testing
- Oral anticoagulant
- Where
- Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Thrombosis, Bleeding
Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery.
The goal of this retrospective clinical trial is to find out association antiplatelet and anticoagulant therapy with perioperative complications in non-cardiac vascular surgery in patients .
- Conditions
- Thrombosis, Bleeding, Cerebral Hypoxia During and/or Resulting From A Procedure
- Trial name
- NCT07358416
- Testing
- Aspirin, Clopidogrel, Ticagrelor
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Non-valvular Atrial Fibrillation
Exploratory Observation of Two Short-term Regimens After LAA Occlusion by LAMax LAAC® Device for Subjects With Non-valvular Atrial Fibrillation
This is a prospective, single-center, randomized, exploratory clinical observation to explore the overall benefit of short-term dual antiplatelet or novel oral anticoagulant regimens after left atrial appendage (LAA) occlusion by…
- Trial name
- NCT05761704
- Testing
- Dual antiplatelet, Novel oral anticoagulant
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine, Thrombosis
Thrombophilia and Migraine, Are They Related?
Migraine was described as related to stroke in adults and children as well. Complete thrombophilic status was not study in large groups of pediatric patients.
- Conditions
- Migraine, Thrombosis, Thrombophilia
- Trial name
- NCT00457184
- Testing
- Blood tests
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Retinal Vein Occlusion
Retrospective Data Analysis of Patients Treated for Macular Edema Due to Central Retinal Vein Occlusion
The objective of this retrospective chart review is to evaluate drug utilization, usage patterns and indication of effectiveness Eylea in the routine clinical (real-life) management of patients who suffer from ME (Macular Edema)…
- Trial name
- RETRO CRVO (NCT02645747)
- Testing
- Aflibercept (Eylea, BAY86-5321)
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- Bayer
Cardiovascular Diseases
Use of the Quantra QPlus Sytem in Cardiac Surgery
Single center retrospective study evaluating the impact of using the Quantra QPlus System to guide transfusion decisions on postoperative outcomes in patients undergoing cardiac surgery.
- Trial name
- NCT05501730
- Testing
- Quantra QPlus System
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- HemoSonics LLC
Coagulation
Effectiveness of Plasma Transfusions in Critical Care Patients
Measuring the effectiveness of plasma transfusions in critical care
- Trial name
- NCT00302965
- Testing
- Frozen Plasma
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ottawa Hospital Research Institute
Thrombosis
Heparin Versus Lepirudin Flushes in Preventing Blockage of Venous Access Devices
This study will compare the effectiveness of two blood thinners, heparin and lepirudin, in preventing withdrawal occlusion (blockage) in a venous access device (VAD).
- Trial name
- NCT00039767
- Testing
- Lepirudin
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Venous Thromboembolism, Malignancy
Mortality Due to Malignancy in Patients With Idiopathic Venous Thromboembolism
Background Patients with an idiopathic venous thromboembolism (IVTE) appear to have a risk of approximately 10% for symptomatic malignancy within 3 years after the IVTE.
- Trial name
- Trousseau (NCT01088334)
- Testing
- screening
- Where
- 10 sites in Netherlands
- Volunteers
- 630 people
- Sponsor
- Slotervaart Hospital