Clinical trials: Blood Clotting
Hemophilia
Motor Proficiency of People With Bleeding Disorders Using the BOT-2 (TM)
The purpose of this study is to find out if gross motor skills of children and young adults with bleeding disorders are different from those without bleeding disorders.
- Trial name
- NCT02279199
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Senile Purpura
Factors Associated With Dermatoporosis
Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.
- Trial name
- FAWD (NCT05037604)
- Testing
- Questionnaire about associated factors, Self questionnaire diagnostic tool, Physical Examination
- Where
- Mexico
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Infant Development, Infant,Premature
Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy
The study seeks to determine the efficacy of non-nutritive suck (NNS) training using a pacifier-activated device (PAM) with mothers' voice to condition suck-strength and rhythmicity, in improving the feeding and developmental…
- Conditions
- Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy
- Trial name
- NCT03230032
- Testing
- pacifier-activated device
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Hemophilia A
Emotions in the Communication and Relationship Styles of Parents With Hemophilic Children.
Severe hemophilia is a rare, inherited, X-linked disorder. Currently, standard therapy involves ev infusion of drugs from a very young age.
- Trial name
- NCT05754619
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Thrombosis
Pharmacogentic Screening of Coumarine Based Oral Anticoagulant Using Next Generation Seguencer
As drug response is a complex trait in the majority of cases using an optimal starting dose for an individual may reduce the time taken to reach a stable INR, and reduce the risk of having either a high INR (with a risk of…
- Trial name
- NCT03180567
- Testing
- Genetic Mutations
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Venous Thromboembolism, Antenatal Deep Vein Thrombosis
LMWH Compliance in Pregnancy
This is a prospective chart study that will aim to assess objective data on compliance levels to low molecular weight heparin (LMWH) injections among pregnant and postnatal women undergoing VTE thromboprophylaxis treatment at…
- Trial name
- NCT05066867
- Testing
- Smart sharps bin - collects data on compliance
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cork University Maternity Hospital
HIV-1 Infection
Targeting Platelets in Chronic HIV Infection
Advances in antiretroviral therapy (ART) have resulted in increased survival of the HIV-infected population; however, this gain in longevity is associated with an increased risk of cardiovascular disease (CVD).
- Trial name
- NCT02578706
- Testing
- Clopidogrel, Aspirin
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Deep Vein Thrombosis
Targeted Metabolic Profiling in Deep Vein Thrombosis
Deep venous thrombosis(DVT) is a blood clot, usually affecting the legs, causing pain, swelling, and redness. The clot damages the veins, which can result in chronic pain, swelling and ulceration.
- Trial name
- NCT04096755
- Testing
- Procedure
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Clotting and Bleeding Disorders, Child Development
Determination of ClotPro Paediatric Reference Range Study
A new thromboelastometry analyser (ClotPro, Enicor GmbH, Munich, Germany) with improved technology was developed. This device has an improved new-generation viscoelastometric testing technique and enables the detection and…
- Conditions
- Clotting and Bleeding Disorders, Child Development, Infant Development, Coagulopathy
- Trial name
- NCT04190615
- Testing
- thromboelastometry test (TEM test)
- Where
- Slovakia
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- National Institute of Children's Diseases, Slovakia
Deep Vein Thrombosis
Improving Lower Limb Blood Flow in Healthy Adult Volunteers
The THRIVE-1 study will examine novel methods for enhancing blood flow in the lower limb using electrical stimulation. Increases in lower limb blood flow improve venous return and thereby reduce venous stasis.
- Trial name
- THRIVE-1 (NCT01981733)
- Testing
- geko
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Artery Disease, Peripheral, Aortic Diseases
Relationship Between Morbimortality and Basal Activated Clotting Time (ACT) in Patients Undergoing Vascular Surgery
Check whether patients with higher comorbidity and risk of complication, estimated using the V (p) -POSSUM score, ACS NSQIP and the ASA classification, present higher baseline activated clotting time values.
- Conditions
- Artery Disease, Peripheral, Aortic Diseases, Carotid Artery Diseases, Other Disease
- Trial name
- NCT04703582
- Testing
- Activated clotting time
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obstetric Hemostasis, Coagulation
Reference Range Study for the Quantra System With the QStat Cartridge in Obstetric Patients
This study will determine reference range intervals for the parameters reported by the Quantra System with the QStat Cartridge in the last trimester of non-laboring pregnant women with an uncomplicated pregnancy
- Trial name
- NCT06415760
- Testing
- Quantra System
- Where
- 3 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- HemoSonics LLC
Acute Coronary Syndrome
Antithrombotic Effects of Ticagrelor Versus Clopidogrel
The purpose of this study is to determine whether treatment with ticagrelor (plus aspirin and bivalirudin) is more effective than treatment with clopidogrel (plus aspirin and bivalirudin).
- Trial name
- NCT01642238
- Testing
- Ticagrelor + ASA + Bivalirudin, Clopidogrel + ASA + Bivalirudin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Juan J Badimon
Hip Fracture of Intertrochanteric Type, Thromboembolic Event
Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis
Hip fracture is a common and severe disease in elderly patients. The question of the study is whether elderly patients with severe osteopenia have significantly lower levels of the collagen-binding protein Hsp47 than relatively…
- Conditions
- Hip Fracture of Intertrochanteric Type, Thromboembolic Event, Osteopenia, Thrombosis Embolism
- Trial name
- HSP 47 (NCT06959017)
- Testing
- Gene Expression Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Thromboembolic Disease
Safety of Direct Oral Anticoagulant During Pregnancy
Pregnancy is a major risk factor of thromboembolic disease (2 to 10 increased risk of thromboembolic event for pregnant women). This risk is related to the physiological changes inducing venous stasis and hypercoagulability.
- Trial name
- SACOD (NCT06179823)
- Where
- France
- Volunteers
- 1,755,558 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Polycythemia Vera, Essential Thrombocythemia
Myeloproliferative Neoplasms: an In-depth Case-control Study
There is a paucity of data on the aetiology of myeloproliferative neoplasms (MPNs). The investigators conducted a systematic review of the literature which identified several cohort and case-control studies that have investigated…
- Conditions
- Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis
- Trial name
- MOSAICC (NCT01831635)
- Testing
- Methodological pens, Methodological compensation, Methodological trolley tokens
- Where
- 3 sites in United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Cardiometabolic Health
Effect of Differently Fed Farmed Gilthead Sea Bream Consumption
The trial was a double-blind randomized dietary intervention study with a 1:1 allocation ratio, conducted in accordance with the Declaration of Helsinki.
- Trial name
- NCT05417191
- Testing
- Conventional fish, Enriched fish
- Where
- Greece
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Venous Thromboembolism
Detecting Circulating Emboli in Patients with Acute Venous Thromboembolism
The purpose of this study is to further evaluate and adjust the photoacoustic flow cytometry device and its use in detecting circulating emboli.
- Trial name
- PAFC (NCT02735759)
- Testing
- Photoacoustic flow cytometry device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
Congenital Bleeding Disorder, Haemophilia A
A Single Dose Trial Investigating Safety and Local Tolerability of Ascending Doses of Long Acting Activated Recombinant Human Factor VII in Healthy Male Volunteers
This trial is conducted in Europe. The aim of this clinical trial is to investigate the safety, local tolerability and pharmacokinetic profile (the determination of the concentration of the administered medication in blood over…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A, Haemophilia B, Healthy
- Trial name
- NCT00951873
- Testing
- activated recombinant human factor VII, long acting
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.