Clinical trials: Blood Donors
Blood Donation
Sucrosomial Iron and Iron Sulphate to Blood Donors
2 different oral iron supplementations after blood donation are compared.
- Trial name
- NCT05678647
- Testing
- Sucrosomial Iron, Iron Sulfate
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uppsala University Hospital
Blood Donation
Enhancing Blood Donation at Schools and Beyond in Malawi
First developed in Zimbabwe, Club 25 is an initiative to promote blood donation among young people, who present a low-risk population for the spread of transfusion transmissible infections (TTIs).
- Trial name
- NCT06138899
- Testing
- Club 25
- Where
- Malawi
- Volunteers
- 35,516 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
RATIONALE: Giving chemotherapy and total-body irradiation (TBI) before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells and helps stop the patient's immune system from rejecting the donor's stem…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT01076270
- Testing
- plerixafor, filgrastim, peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Red Blood Cell Donation
Clinical Investigational Protocol for 2 RBC Single Unit Recovery on MCS®+ 8150 Using LN832 Disposable Sets (US)
The purpose of this study is to validate that single units of RBCs collected by the Haemonetics MCS®+ 8150 system using LN832 disposable sets during an interrupted double red cell collection protocol meet all in vitro FDA…
- Trial name
- NCT01764061
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation
G6PD Deficiency
Effect of G6PD Deficiency on Red Blood Cell Storage
The proposed study will determine whether G6PD-deficient RBCs store differently than normal RBCs under standard blood banking conditions.
- Trial name
- NCT04081272
- Testing
- Sodium Chromate Cr51
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Lymphoma, Leukemia
Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
Background: Patients with cancers of the blood and immune system often benefit from transplants of stem cells from a genetically well-matched sibling.
- Conditions
- Lymphoma, Leukemia, Myeloproliferative Disorders, Multiple Myleoma
- Trial name
- NCT00074490
- Testing
- Rituximab, Fludarabine, Etoposide
- Where
- 2 sites in United States
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Polycystic Ovary Syndrome, Infertility, Female
Effect of Nitric Oxide Donors on Uterine and Subendometrial Blood Flow in Patients With Unexplained Infertility
The purpose of the study to evaluate effect of nitroglycerin trans-dermal patches on uterine and sub-endometrial blood flow in women with unexplained infertility.
- Trial name
- NCT03481582
- Testing
- Nitroglycerin, Three dimensional power doppler
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Primary Myelofibrosis, Secondary Myelofibrosis
Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis
This early phase I trial studies the side effects of combination chemotherapy, total body irradiation, and donor blood stem cell transplant in treating patients with primary or secondary myelofibrosis.
- Trial name
- NCT03426969
- Testing
- Cyclophosphamide, Filgrastim, Fludarabine Phosphate
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Fatigue, Iron Deficiency
Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors
The purpose of this study is to determine the subjective response of iron substitution (Tardyferon®) on fatigue in women blood donors with a mean serum ferritin < 30ng/ml and to assess variation of ferritin and hemoglobin after a…
- Trial name
- ferdon (NCT00689793)
- Testing
- Ferrous sulphate
- Where
- Switzerland
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Hepatitis C
A Study of the Use of Hepatitis C Positive Donors for Hepatitis C Negative Lung Transplant Recipients With Post-transplant Treatment With Mavyret
Patients who are Hepatitis C Negative (HCV negative) and are on the waiting list for a lung transplant at NYULH who consent to participate in this study will receive a lung transplant from a deceased donor that is HCV positive.
- Trial name
- NCT03523871
- Testing
- Mavyret
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
COVID-19 Respiratory Infection
COVID-19 Seroprevalence in Pregnant Women and Blood Donors
The study aims to measure the SARS-CoV-2 seroprevalence (ie. the proportion of people with antibodies against the virus) in pregnant women and blood donors in an administrative area of France, and to determine whether these…
- Trial name
- CoVERED (NCT04893057)
- Where
- France
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Autologous Blood Transfusion, Physical Performance
Transfusion of Whole Blood to Military Forces in a Combat Situation
During military action there might be situations where civil requirements for blood transfusion are not obtainable. Numerous warfare experiences suggest that administration of whole blood to a patient with uncontrollable…
- Conditions
- Autologous Blood Transfusion, Physical Performance, Donor Safety
- Trial name
- NCT04496700
- Testing
- Whole blood donation and transfusion
- Where
- 2 sites in Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Blood Donors
Community-Based Communication Approaches for Blood Donation in Ghana
DESIGN This pilot study utilizes a mixed-methods approach to develop a novel docu- drama communication strategy, design WhatsApp intervention, evaluate the feasibility of a larger pragmatic randomized controlled trial (RCT) of…
- Trial name
- C-CAD (NCT04783077)
- Testing
- WhatsApp, Control, Docudrama
- Where
- Ghana
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Blood Donors
Effect of a Web Page Based on a Motivational Video for Voluntary Blood Donation
Voluntary blood donation is currently a key issue in many countries, as the shortage of voluntary donors results in a deficit in the supplies of the Blood Banks of the hospitals.
- Trial name
- NCT04088695
- Testing
- Video through a web page, Informative text
- Where
- Peru
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Platelet Dysfunction in Blood Donors
Platelet Dysfunction in Blood Donors
Platelets are circulating blood cells. They bind to each other and to the damaged vessel wall to prevent excessive bllod loss. Unlike quantitative platelet defects, there is no automated, simple test to diagnose qualitative…
- Trial name
- DysPlaq (NCT03599219)
- Testing
- sample
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Etablissement Français du Sang
Living Kidney Donation
The Living Kidney Donor Safety Study
The main goal of this study is to understand the long-term effects of kidney donation on blood pressure, kidney function, and patient-reported health-related quality of life.
- Trial name
- LKD (NCT00936078)
- Where
- 13 sites in Australia, Canada
- Volunteers
- 1,438 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Health Status Unknown
Studying Umbilical Cord Blood From African-American Donors
RATIONALE: Studying umbilical cord blood in the laboratory and gathering information about current and previous pregnancies from African-American umbilical cord blood donors may help doctors learn more about the umbilical cord…
- Trial name
- NCT00717535
- Testing
- cryopreservation, questionnaire administration, study of socioeconomic and demographic variables
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Blood And Marrow Transplantation
Plerixafor for Stem Cell Mobilization in Normal Donors
The goal of this clinical research study is to learn if treating stem cell donors with filgrastim (G-CSF) and plerixafor (Mozobil®) can cause them to produce a higher number of blood stem cells than filgrastim by itself.
- Trial name
- NCT01818284
- Testing
- Filgrastim, Plerixafor, Apheresis Procedure
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Blood Donors
Evaluation of Whole Blood With CPD Anticoagulant and AS-7/SOLX Additive Solution
This study will evaluate a new blood collection and filtration system that is intended to be used to collect, filter, separate and store red blood cells and, separately, plasma.
- Trial name
- NCT02145507
- Testing
- SOLX (Investigational), AS-3 (Control)
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation
Transmission, Blood, Recipient/Donor
Procedure For The Reference Range Study For Absolute MA
CLSI guidelines shall be followed to gather data from a minimum of one hundred and twenty normal donors to create reference intervals for various Haemonetics reagents.
- Trial name
- NCT02110576
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation