Clinical trials: Blood Loss, Surgical
Stroke
Can Acupuncture Benefit Surgical Patients With Haemorrhagic Stroke?
The purpose is to establish whether acupuncture in addition to conventional rehabilitation programme can improve the functional outcome and quality of life of surgical patients with haemorrhagic stroke, as compared to…
- Trial name
- NCT01037894
- Testing
- Acupuncture, Conventional rehabilitation
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Chinese University of Hong Kong
Tranexamic Acid, Burns
TRANexamic Acid to Reduce Bleeding in BURN Surgery
Excision and grafting in burn patients can lead to severe blood loss. A preliminary study conducted in Saint Joseph Saint Luc Hospital showed that the total median blood loss was 1412 mL (1).
- Conditions
- Tranexamic Acid, Burns, Surgery, Wounds and Injuries
- Trial name
- TRANBURN (NCT03113253)
- Testing
- Tranexamic Acid
- Where
- 4 sites in France
- Volunteers
- 121 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Spinal Tumor, Spinal Injury
Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery
This clinical trial evaluates the effectiveness and safety of a collagen-based hemostatic agent containing thrombin in patients undergoing spinal surgery.
- Conditions
- Spinal Tumor, Spinal Injury, Hemostasis, Spinal Stenosis
- Trial name
- NCT07354178
- Testing
- CollaStat®, Floseal®
- Where
- 3 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- DALIM TISSEN Co., Ltd.
Osteoarthritis, Intraoperative Bleeding
Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty
Hypotheses: Primary - A weighted dose of 20 mg/kg of tranexamic acid will be more efficacious than a single uniform dose of 1 gram in primary total knee arthroplasty (TKA) cases.
- Trial name
- NCT01651806
- Testing
- Tranexamic Acid standard dose, Females Tranexamic Acid weighted dose, Females receiving a uniform dose of TA
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Hyperthermic Intraperitoneal Chemotherapy, Hepatocellular Carcinoma
Surgical Resection Combined With Intraperitoneal Hyperthermic Chemotherapy
Patients with ruptured liver cancer and bleeding after surgical resection were included according to the criteria of admission, and the patients were divided into experimental and control groups.
- Conditions
- Hyperthermic Intraperitoneal Chemotherapy, Hepatocellular Carcinoma, Ruptured Liver
- Trial name
- NCT06247293
- Testing
- intraperitoneal hyperthermic perfusion chemotherapy
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Aneurysmal Subarachnoid Hemorrhage
Clazosentan in Aneurysmal Subarachnoid Hemorrhage
The aim of this study is to demonstrate that clazosentan, administered as a continuous intravenous infusion at either 5 mg/h or 15 mg/h until Day 14 post aneurysmal subarachnoid hemorrhage (aSAH), reduces the incidence of…
- Trial name
- CONSCIOUS-3 (NCT00940095)
- Testing
- Clazosentan 5 m/h, Clazosentan 15 mg/h
- Where
- 145 sites in United States, Argentina and 26 more
- Volunteers
- 577 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Postoperative Complications, Hernia
Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?
The purpose of this study is to determine whether drainage after prosthetic repair of incisional abdominal hernias increases or decreases complications such as infection, seromas and hematomas.
- Trial name
- NCT00478348
- Testing
- Prosthetic repair of abdominal incisional hernia
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Lausanne Hospitals
Ruptured Abdominal Aortic Aneurism
START - Early Thrombocyte Administration to Patients With Ruptured Abdominal Aortic Aneurism
The purpose of this study is to investigate the effect of platelet infusion prior to transfer to a vascular surgical department in patients with a ruptured abdominal aortic aneurism.
- Trial name
- rAAA (NCT01291290)
- Testing
- Platelet
- Where
- Denmark
- Volunteers
- 420 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Surgery, Hemorrhage
Impact of Combination of Clopidogrel With Aspirin on Postoperative Bleeding in Coronary Surgical Patients
Aims Aspirin combined with clopidogrel is the treatment of choice for acute coronary syndromes. Although the maintenance of aspirin until surgery does not affect postoperative bleeding after coronary artery bypass graft (CABG)…
- Trial name
- ICARE (NCT01216150)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Cardiac Surgical Procedures, Retained Blood Syndrome
CPPF After General Cardiac Surgery
In two randomized clinical trials the investigators have demonstrated that continuous postoperative pericardial flushing (CPPF) therapy can reduce postoperative blood loss and bleeding-related complications after cardiac surgery…
- Conditions
- Cardiac Surgical Procedures, Retained Blood Syndrome, Cardiac Tamponade, Postoperative Hemorrhage
- Trial name
- FLUID (NCT05308589)
- Testing
- CPPF
- Where
- 4 sites in Netherlands
- Volunteers
- 164 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Subdural Hematoma
The Finnish Study of Intraoperative Irrigation Versus Drain Alone After Evacuation of Chronic Subdural Hematoma (FINISH)
FINISH-trial is a prospective, randomized, controlled, parallel group non-inferiority trial comparing single burr-hole evacuation of chronic subdural hematoma (CSDH) with intraoperative irrigation (IR) and evacuation of CSDH…
- Trial name
- FINISH (NCT04203550)
- Testing
- Intraoperative irrigation, No irrigation
- Where
- Finland
- Volunteers
- 587 people
- Sponsor
- Helsinki University Central Hospital
Traumatic Intracranial Subarachnoid Hemorrhage
Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
Brain injuries are common and challenging problems faced by emergency physicians. These diagnoses may include traumatic intracerebral hemorrhage, subarachnoid hemorrhage, ruptured cerebral aneurysms, unruptured cerebral…
- Trial name
- NCT06136078
- Testing
- rate of appropriate and inappropriate transfers from Methodist interfacility transfers
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Methodist Health System
Hysterectomy for Abnormal Uterine Bleeding
Laparoscopic Gynecology Curriculum for Residents
Gynecologists are currently using laparoscopy to perform many surgeries traditionally approached by laparotomy. The technical skills required for laparoscopic surgery are different than the skills required for laparotomy, causing…
- Trial name
- NCT01916343
- Testing
- Study Laparoscopic Curriculum
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Bloodloss, Surgical Procedures, Operative
Outcomes and Safety Trial Investigating Ecallantide's Effect on Reducing Surgical Blood Loss Volume in Subjects at High Risk of Bleeding Exposed to Cardio-pulmonary Bypass During Cardiac Surgery
A Phase 2 Randomized Double-Blind Active-Controlled Study in Subjects Exposed to Cardio-pulmonary Bypass During Cardiac Surgery at High Risk of Bleeding
- Trial name
- CONSERV-2 (NCT00888940)
- Testing
- Ecallantide, Cyklokapron(R)
- Where
- 34 sites in United States, Germany and 1 more
- Volunteers
- 243 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Postoperative Pain Control in Surgical Neonates
The Use of Ketorolac in Surgical Neonates
The general purpose of this study is to characterize the safety profile of ketorolac in infants age 0-3 months. Our hypothesis is that ketorolac is safe in neonates, and effective in controlling pain with less narcotic…
- Trial name
- NCT01667120
- Testing
- Ketorolac
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Deviation Septum Nasal
A Comparison of Esmolol and Remifentanil to Reduce Blood Loss
In this prospective randomized study we aimed to compare the effects of esmolol and remifentanil on intraoperative bleeding surgical field conditions in nasal surgery
- Trial name
- NCT01752959
- Testing
- Remifentanil, Esmolol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Clarify the Therapeutic Differences Between Robot Assisted Endoscopic Clearance and Traditional Puncture and External Drainag
Effect of Minimally Invasive Surgical Assisted by Robots on Intraventricular Hemorrhage
Clarify the therapeutic differences between robot assisted endoscopic clearance and traditional puncture and external drainage, and establish a new minimally invasive surgical diagnosis and treatment strategy for intraventricular…
- Trial name
- NCT06486480
- Testing
- Using robot assisted endoscopy to clear intraventricular hemorrhage
- Volunteers
- 143 people
- Sponsor
- Jin Hu
Intraoperative Bleeding
The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women
A full medical history will be obtained from all participants. Obstetric ultrasonography and laboratory tests will be performed.According to group assignment, either 1 g(10 mL) tranexamic acid stored in a dry container at 15…
- Trial name
- NCT03820206
- Testing
- Tranexamic Acid, Cesarean section
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Blood Loss, Surgical, Prostate Cancer
Safety Study of Hemospan® in Prostatectomy Patients
This is a progressive dose escalation study designed to evaluate the safety of Hemospan compared to a standard crystalloid solution (Ringer's lactate) in elective surgery patients undergoing total prostatectomy procedures with…
- Conditions
- Blood Loss, Surgical, Prostate Cancer, Surgery
- Trial name
- NCT00425334
- Testing
- Hemospan (MP4OX), Ringer's lactate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sangart
Cesarean Section, Blood Loss During Surgery
Tranexamic Acid to Reduce Blood Loss in Women Having Planned Cesarean Section
This clinical trial was done to find out if tranexamic acid (TXA) can safely reduce the amount of blood loss during cesarean (C-section) deliveries.
- Trial name
- NCT07013812
- Testing
- Tranexamic Acid (IV), Dextrose 5% (D5W)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Combined Military Hospital Multan