Clinical trials: Blood Platelet Disease
Hair Transplantation, Cicatricial Alopecia
Hair Transplantation in Cicatricial Alopecia
follicular unit extraction as a method of hair transplantation in cicatricial alopecia
- Trial name
- NCT04472715
- Testing
- follicular unit extarcation and platelet rich plasma
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Traumatic Head Injury, Intracranial Hemmorhage
Safety of Platelet Transfusion in Patients on Antiplatelet Therapy With Traumatic Head Injury
The objective of this study is to determine if the administration of platelets will improve outcome in patients with ICH who are being treated with either aspirin, a thienopyridine (ticlodipine, clopidogrel, prasugrel) or a…
- Conditions
- Traumatic Head Injury, Intracranial Hemmorhage, Anti-platelet Therapy
- Trial name
- PUNCH (NCT01810276)
- Testing
- Saline, Platelets
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Christiana Care Health Services
Anal Fistula, Complex Perianal Fistula
Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula Healing
The average success rate for healing and remission of complex perianal fistulas, idiopathic or Crohn's-related, is approximately 50%.
- Trial name
- NCT06632418
- Testing
- RhPDGF-BB
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Alexander Hawkins
Purpura, Schoenlein-Henoch, Graft Versus Host Disease
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases
OBJECTIVES: I. Determine whether there is prompt engraftment after autologous peripheral blood stem cell transplantation using filgrastim (G-CSF) mobilization in patients with life threatening autoimmune diseases. II.
- Conditions
- Purpura, Schoenlein-Henoch, Graft Versus Host Disease, Anemia, Hemolytic, Autoimmune, Rheumatoid Arthritis
- Trial name
- NCT00006055
- Testing
- anti-thymocyte globulin, cyclophosphamide, cyclosporine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Fairview University Medical Center
HIV
Tenofovir Abacavir Platelet Activation Study
Some but not all observational studies have found that current exposure to abacavir is associated with increased risk of cardiovascular events such as myocardial infarction, stroke and cardiovascular death.
- Trial name
- TAPAS (NCT02093585)
- Testing
- abacavir (600 mg QD), tenofovir (245 mg QD)
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Jan Gerstoft
Heparin-induced Thrombocytopenia
Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia
Heparin is an anticoagulant (blood thinner) that is commonly used to treat patients with heart attacks and patients with blood clots in their legs or lungs (venous thrombosis).
- Trial name
- NCT01598168
- Testing
- Rivaroxaban
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- McMaster University
Carpal Tunnel Syndrome (CTS)
PRP Versus Saline Hydrodissection for CTS RCT
This single-center, single-blind, randomized controlled trial compared two injectates used for ultrasound-guided hydrodissection of the median nerve in adults with carpal tunnel syndrome: autologous platelet-rich plasma (PRP) and…
- Trial name
- NCT07904650
- Testing
- Autologous platelet-rich plasma, Normal Saline (0.9% Sodium Chloride), Ultrasound-guided median nerve hydrodissection
- Where
- Poland
- Volunteers
- 21 people
- Sponsor
- Medical University of Lodz
Thrombocytopenia
Evaluating the Presence of Blood Clots in People With Heparin-Induced Thrombocytopenia (HIT) (The HOT Study)
Heparin-induced thrombocytopenia (HIT), a condition characterized by low platelet levels and possible blood clots, occurs in a small number of people after treatment with the drug heparin.
- Trial name
- HOT (NCT00594685)
- Where
- 21 sites in United States
- Volunteers
- 10 people
- Sponsor
- Carelon Research
Scleroderma, Systemic
Platelet Gel in Systemic Sclerosis
Systemic sclerosis (scleroderma; SSc) is a connective tissue disease characterized by a progressive fibrosis of the skin and visceral organs.
- Trial name
- NCT00463125
- Testing
- Platelet Gel
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università Politecnica delle Marche
Stroke, Ischemic Attack, Transient
Platelet Reactivity in Acute Non-disabling Cerebrovascular Events
Ticagrelor is a reversible and direct-acting oral antagonist of the P2Y12 (Purinergic receptor P2Y, G-protein coupled, 12) receptor for adenosine diphosphate, which provides faster, greater, and more consistent P2Y12 inhibition…
- Trial name
- PRINCE (NCT02506140)
- Testing
- Ticagrelor and Acetylsalicylic acid, Clopidogrel and Acetylsalicylic acid
- Where
- 25 sites in China
- Volunteers
- 675 people
- Sponsor
- Beijing Tiantan Hospital
Thrombocytopenia, Neutropenia
Study of Drug to Reduce Thrombocytopenia in Patients Receiving Chemo for Ovarian, Fallopian Tube or Peritoneal Cancer
This research study will investigate the safety and effectiveness of two different dose levels of a new, unapproved drug to be given along with the chemotherapy regimens gemcitabine and carboplatin or gemcitabine and cisplatin…
- Conditions
- Thrombocytopenia, Neutropenia, Lymphopenia, Anemia
- Trial name
- NCT00771810
- Testing
- TXA127
- Where
- 6 sites in United States
- Volunteers
- 34 people
- Sponsor
- Tarix Pharmaceuticals
Recurrent Solid Tumor, Refractory Solid Tumor
ODSH + ICE Chemotherapy in Pediatric Solid Tumors
This study will be with pediatric patients who have refractory/recurrent solid tumors. They will receive standard chemotherapy (ICE) and we are investigating if the addition of a new drug, ODSH, will help to increase the time of…
- Conditions
- Recurrent Solid Tumor, Refractory Solid Tumor, Sarcoma, Wilms' Tumor
- Trial name
- NCT02164097
- Testing
- ODSH
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- New York Medical College
Pulp Necrosis, Apical Periodontitis
PRP-Assisted Regenerative Endodontics Versus Conventional Root Canal Treatment in Mature Necrotic Teeth
This clinical trial will compare platelet-rich plasma (PRP)-assisted regenerative endodontic treatment with conventional root canal treatment in mature permanent teeth with pulp necrosis and apical periodontitis.
- Trial name
- NCT07918664
- Testing
- PRP-Assisted Regenerative Endodontic Treatment, Conventional Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- TC Erciyes University
Osteonecrosis
Randomized Clinical Trial for the Treatment of Osteonecrosis of the Femoral Head
Femoral head avascular necrosis is a relatively common disease (10,000 - 20,000 yearly new United States of America cases) characterized by ischemic cell necrosis in a hip proximal epiphysis area frequently requiring total Hip…
- Trial name
- AVN-13 (NCT01892514)
- Testing
- core decompression
- Where
- 3 sites in Italy
- Volunteers
- 104 people
- Sponsor
- Istituto Ortopedico Rizzoli
Heparin-Induced Thrombocytopenia
Heparin-Induced Thrombocytopenia Registry
The purpose of the Heparin Induced Thrombocytopenia Registry is to explore the frequency of heparin-induced thrombocytopenia (HIT) at Brigham and Women's Hospital and to assess its mortality rate.
- Trial name
- HIT (NCT00456326)
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Brigham and Women's Hospital
Allograft
Feasibility Study of Platelet Activation and Inflammatory Response of Platelets in Hematopoietic Stem Cell Allograft Patients Post-transplant: Spontaneously and After Stimulation by an CMV Antigen
Traditionally known for their role in haemostasis, platelets have also an immune role. Platelets play a key role in immune mediator secretion, and interact with innate and adaptive immune cells, contributing to the fight against…
- Trial name
- FIPALLOC (NCT03009708)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Institut de Cancérologie de la Loire
Knee Osteoarthrosis
Participants With Knee Osteoarthrosis
Title: Efficacy and Safety Trial of PRP and ICQ for Elderly Women with KOA Goal: To assess if PRP and ICQ reduce symptoms and improve mobility in elderly women with knee osteoarthritis.
- Trial name
- KOA (NCT06535425)
- Testing
- Platelet-Rich Plasma, Isometric Contractions of Quadriceps, Platelet-Rich Plasma Combined with Isometric Contractions of Quadriceps
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Chengdu Sport University
Androgenetic Alopecia, Alopecia
Study to Assess Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia
The purpose of this study is to determine the efficacy of treatment with Platelet-rich plasma on Androgenetic alopecia (compared with placebo), between six months and baseline.
- Conditions
- Androgenetic Alopecia, Alopecia, Hair Loss
- Trial name
- PRP (NCT02393040)
- Testing
- PRP/Saline
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universitat Internacional de Catalunya
Neoplasms, Thrombocytopenia
Safety and Efficacy of (PN-152,243)/PN-196,444 in the Prevention of Thrombocytopenia
Intensive chemotherapy is associated with significant thrombocytopenia, often requiring platelet transfusion to maintain platelet counts. This investigational drug has demonstrated the ability to increase platelet counts.
- Conditions
- Neoplasms, Thrombocytopenia, Multiple Myeloma, Lymphoma, Malignant
- Trial name
- NCT00037791
- Testing
- (PN-152,243)/PN-196,444
- Where
- 9 sites in United States, Argentina and 1 more
- Volunteers
- 180 people
- Sponsor
- Pfizer
Knee Osteoarthritis
The Knee Usual Care Evaluation Study
The purpose of this prospective data collection is to track patients who are treated at HSS who are confirmed with knee osteoarthritis.
- Trial name
- KUCE (NCT01905358)
- Where
- United States
- Volunteers
- 906 people
- Sponsor
- Hospital for Special Surgery, New York
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.