Clinical trials: Blood Pressure, Resistant
Postprandial Period, Lipemia
Vascular Effects of Triglyceride-rich Lipoproteins
Many types of cardiovascular disease begin when the layer of cells lining blood vessels (endothelial cells) start to function abnormally.
- Conditions
- Postprandial Period, Lipemia, Vasodilation, Vascular Resistance
- Trial name
- NCT01618071
- Testing
- High-fat meals varying in their fatty acid composition
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity, Insulin Resistance
Effects of Hesperidin on Insulin Sensitivity
This study will examine whether hesperidin, a major component of citrus fruits, affects how the body responds to insulin in healthy and obese people.
- Trial name
- EHIS (NCT01773486)
- Testing
- Hesperidin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Prehypertension, Healthy
Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets
The investigators will be studying the effect of melatonin on blood pressure, insulin resistance, and platelets, along with possible reasons for how melatonin cases these effects.
- Trial name
- NCT03178396
- Testing
- melatonin
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cardiovascular Disease
Impact of Meal Fatty Acids on Postprandial Vascular Reactivity
Cardiovascular disease (CVD) is the leading cause of death in women. Premenopausal women have a lower risk of CVD compared with men of a similar age. However, the incidence of CVD increases greatly after the menopause.
- Trial name
- DIVAS-2 (NCT02144454)
- Testing
- Saturated fat, Monounsaturated fat, n-6 polyunsaturated fat
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cardiovascular Disease, Aging
Effects of Age and Exercise on Blood Pressure Regulation
The purpose of this study is to investigate the effects of age, exercise and cardiovascular disease on blood pressure.
- Trial name
- NCT00319397
- Testing
- Exercise-Training Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Hypertension
Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow
The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements…
- Trial name
- NCT00018304
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cardiovascular Diseases, Vascular Diseases
Influence of Age, Weight and Ethnic Background on Blood Pressure
Hypertension, also known as high blood pressure, is a chronic medical condition, in which the blood pressure is elevated. This is a common condition, which can lead to severe complications such as cardiovascular disease, heart…
- Conditions
- Cardiovascular Diseases, Vascular Diseases, Hypertension
- Trial name
- AWE (NCT03014791)
- Testing
- Brief lifestyle/medical history questionnaire, Anthropometric measures, Blood pressure and arterial stiffness
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiovascular Risk Factor
Choline and Cardiometabolic Health
Trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to be predictive of cardiovascular…
- Trial name
- NCT04764162
- Testing
- Choline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Prehypertension, Blood Pressure
The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on body composition, blood pressure, insulin resistance, and academic self-efficacy in prehypertensive adolescent obese girls.
- Conditions
- Prehypertension, Blood Pressure, Abdominal Obesity, Self Efficacy
- Trial name
- NCT03898518
- Testing
- 12-week jump rope exercise program
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Ageing, Blood Flow Restriction
Comparing Vascular Responses to Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults
Aging leads to declines in functional capacity and effort tolerance. Muscle strength remains stable from ages 25 to 50 but declines significantly after age 60, affecting activities like stair climbing and walking, reducing…
- Trial name
- HOLD TIGHT (NCT06596304)
- Testing
- Low intensity-resistance training with lower limb blood flow restriction, High Intensity Resistance Training
- Where
- 2 sites in Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Diabetes, Hypertension
The Effect of Dietary Nitrate on Blood Pressure, Insulin Sensitivity, and Vascular Function in Type 2 Diabetes
Dietary nitrate supplementation has previously been shown to reduce blood pressure in healthy volunteers. The investigators wished to see whether this would be replicated in subjects with type 2 diabetes and age matched healthy…
- Trial name
- NCT04076007
- Testing
- Beetroot juice, Nitrate depleted beetroot juice
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Metabolic Syndrome
Effects of a Supportive Mobile Health for Life Style Modification on Blood Pressure and Insulin Resistance Improvement in People With Metabolic Abnormalities
The purpose of this randomized study is to assess the efficacy of a mobile application for the improvement of blood pressure and insulin resistance in people with metabolic abnormalities.
- Trial name
- NCT03300271
- Testing
- Mobile application for self monitoring, Education, Mobile application for personal coaching
- Where
- South Korea
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Metabolic Syndrome
ButCoIns - Metabolic Effects of Resistent Starch and Arabinoxylans in Subjects With Metabolic Syndrome
Background Life style related disease is an increasing problem all over the world. The Metabolic Syndrome (MetS) is a condition characterized by abdominal obesity, high blood lipids, high blood pressure and slightly elevated…
- Trial name
- ButCoIns (NCT01584427)
- Testing
- Healthy Carbohydrate Diet vs. Western Style Diet
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Blood Pressure
Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure
The study aimed to evaluate the chronic and acute effects of high-intensity resistance training on blood pressure and its hemodynamic and neural determinators in healthy normotensive older subjects.
- Trial name
- RTBP (NCT01113203)
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Endothelial Dysfunction, Hypertension
FFA-Induced Hypertension and Endothelial Dysfunction
The study is a prospective open label study to examine the effects of oral and intravenous fat load on blood pressure, endothelial function, sympathetic activity, and oxidative stress in obese healthy subjects.
- Trial name
- NCT00589888
- Testing
- Intralipid 20% @ 20cc/hour, Intralipid 20%@ 40cc/hour, Normal Saline
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension
Isometric Handgrip Exercise for Blood Pressure Management
Recent meta-analyses suggest isometric resistance training (IRT) may be superior to aerobic exercise for lowering blood pressure.
- Trial name
- NCT02458443
- Testing
- Isometric resistance training
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of New England, Australia
Hypertension, Cardiovascular Diseases
Cardiovascular Disease Risk Factors in Chinese American Immigrants
The Chinese population is currently the fastest growing ethnic group in New York City (NYC). Research has shown that Chinese immigrants living in NYC have higher rates of cardiovascular disease (CVD) than individuals in China.
- Conditions
- Hypertension, Cardiovascular Diseases, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- CHA-CHA (NCT00362128)
- Where
- United States
- Volunteers
- 2,072 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Arterial Hypertension, Menopause
Blood Pressure and Cardiometabolic Risk (Diet-to-HTN)
Obesity is a significant health issue that increases the risk of serious cardiovascular problems. In recent years, two dietary methods, the Ketogenic Diet (KD) and Intermittent Fasting (IF), have become popular for their…
- Conditions
- Arterial Hypertension, Menopause, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT06457711
- Testing
- Free diet Group (FDG), Very low Calorie Ketogenic Diet Group (VLCKDG), Intermittent Fasting Group (IFG)
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Primary Hypertension, Secondary Hypertension
HaemoDYNAMICs in Primary and Secondary Hypertension
The primary aim of the present study was to examine the haemodynamic changes in primary hypertension and secondary hypertension (renal diseases, endocrine diseases, obesity-associated hypertension) with a non-invasive…
- Conditions
- Primary Hypertension, Secondary Hypertension, Aortic Stenosis, Renal Insufficiency
- Trial name
- DYNAMIC (NCT01742702)
- Testing
- Nitroglycerin 0.25 mg (single dose, no longer given since January 2017), Salbutamol 400 µg (single dose, no longer given since January 2017), L-arginine (10 min infusion, no longer given since January 2017)
- Where
- 2 sites in Finland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tampere University