Clinical trials: Blood Pressure, completed
Metabolic Syndrome
Green Coffee Extract and Metabolic Syndrome
Metabolic syndrome (Mets) is an assemblage of risk factors which can increase the risk of developing type 2 diabetes mellitus and cardiovascular disease.
- Trial name
- NCT02764957
- Testing
- green coffee extract
- Where
- Iran
- Volunteers
- 43 people
- Sponsor
- National Nutrition and Food Technology Institute
Chronic Kidney Disease, Endothelial Dysfunction
Study of Protective Effects of Paricalcitol on Inner Layer of Vessels and Its Protective Effect on Inflammation
The study is about possible protective effects of paricalcitol (Zemplar) upon inflammation, blood pressure and kidney function. Kidney Inflammation occurs when white blood cells become abnormally stimulated and accumulate in the…
- Conditions
- Chronic Kidney Disease, Endothelial Dysfunction, Inflammation, Hypertension
- Trial name
- NCT00428246
- Testing
- paricalcitol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Hypertension
Evaluation of Atacand® (Candesartan) in Daily Medical Practice
This open label, non-interventional study is to show the efficacy of antihypertensive treatment with Atacand in hypertensive patients.
- Trial name
- NCT00837720
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Physiological Monitoring, Critically Ill
Comparative in Patient, Non-intervention Study of the Remote Physiological Monitoring System (RPM™) vs Standard Physiological Monitoring Devices
The Remote Physiological Monitoring System (RPM™) is a wireless technology for physiological monitoring. The RPM™ is designed to capture, transmit and remotely monitor the vital signs of a patient or group of patients.
- Trial name
- NCT00664924
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Intracranial Pressure, Circulation System
The Effect of Arterial Carbon Dioxide Levels on Cerebral Blood Flow and Cerebral Autoregulation in the Steep Trendelenburg Position During Robot-assisted Prostatectomy, and Its Effect on Postoperative Cognition
Patients scheduled for robot-assisted prostatectomy will be randomized to either high or low concentrations of carbon dioxide in the blood.
- Conditions
- Intracranial Pressure, Circulation System, Cerebral Perfusion Pressure, Cognitive Function
- Trial name
- TILTDOWN-3 (NCT06865027)
- Testing
- Ventilation strategy
- Where
- Norway
- Volunteers
- 46 people
- Sponsor
- University Hospital, Akershus
Hypertension
Sham Controlled Clinical Trial of Renal Denervation in Patients With Resistant Hypertension
The purpose of this study is to assess the efficacy of catheter-based renal denervation in reducing blood pressure in patients with resistant hypertension compared to a sham procedure.
- Trial name
- NCT02444442
- Testing
- Renal Denervation
- Where
- Australia
- Volunteers
- 105 people
- Sponsor
- Baker Heart and Diabetes Institute
Blood Pressure, Perioperative Hypotension
Impact of Continuous Non-invasive Blood Pressure Monitoring on Hypotension in Patients Having Non-cardiac Surgery
This is a randomized trial (1) investigating whether continuous non-invasive finger-cuff blood pressure monitoring reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes of anesthetic…
- Trial name
- NCT04736862
- Testing
- Continuous non-invasive blood pressure monitoring, Intermittent non-invasive blood pressure monitoring
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Intraocular Pressure
Intraocular Pressure (IOP) and Isometric Exercise
The purpose of this study is to investigate changes in intraocular pressure measured continuously during isometric exercise.
- Trial name
- NCT00635180
- Testing
- isometric exercise
- Where
- Norway
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Cardiac Catheterization, Blood Pressure
Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure…
- Conditions
- Cardiac Catheterization, Blood Pressure, Heart Ventricles, Echocardiography
- Trial name
- NCT03243942
- Testing
- Definity
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Thomas Jefferson University
Type 2 Diabetes, Blod Pressure
Vasodilatory and Metabolic Effects of Glucagon-like Peptide-1 in Periphery Circulation in Patients With and Without Type 2 Diabetes Mellitus
Diabetes and high blood pressure are risk factors for developing heart disease. An increase in the number of diabetes patients is expected.
- Conditions
- Type 2 Diabetes, Blod Pressure, Glucagon-like Peptide-1, Human Physiology
- Trial name
- NCT01689051
- Testing
- human glucagon-like peptide 1 (7-36)amide, human glucagon-like peptide 1 (9-36)amide
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Hypertension
Study of the Efficacy and Safety of Aliskiren HCTZ vs Ramipril in Obese Patients (BMI ≥ 30) With Stage 2 Hypertension
Study to Evaluate the Efficacy and Safety of Aliskiren Hydrochlorothiazide (HCTZ) vs Ramipril in Obese patients (BMI ≥ 30) with Stage 2 Hypertension
- Trial name
- ATTAIN (NCT00772577)
- Testing
- Aliskiren Hydrochlorothiazide, Ramipril
- Where
- 6 sites in United States
- Volunteers
- 386 people
- Sponsor
- Novartis
Healthy
Metabolic Syndrome and Leptin Level Associated With Fructose Consumption in Spain
A Food Frequency Questionnaire (FFQ), will be provided to 800 adults to assess overall fructose intake and this will be related to a number of features related to the metabolic syndrome, including serum leptin, characteristic…
- Trial name
- NCT00651001
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hospital Mateo Orfila
Sepsis-Induced Hypotension
A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension
This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on adult patients (18 to 85 years) hospitalized due to a serious infection (called "sepsis") and receiving…
- Trial name
- ESTELLA (NCT06608901)
- Testing
- REGN7544, PB
- Where
- 29 sites in United States, France
- Volunteers
- 76 people
- Sponsor
- Regeneron Pharmaceuticals
Cerebrovascular Circulation
Quantification of Dynamic and Static Cerebral Autoregulation (CA) Under Anaesthesia
Cerebral autoregulation (CA) is the mechanism by which the brain vasculature maintains constancy of cerebral blood flow (CBF). Reliable direct measurements of CBF at different blood pressure levels are difficult because they are…
- Trial name
- SAMBA (NCT03816072)
- Testing
- Phenylephrine infusion, Mechanical ventilation, Propofol
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Transient Hypertension, Pregnancy
CHIPS (Control of Hypertension in Pregnancy Study): A Pilot Trial
Prior to undertaking CHIPS which will be a large and difficult trial, we believe we need to first determine whether clinicians will comply with the interventions of 'less tight' and 'tight' control of dBP, and whether the…
- Trial name
- NCT00187395
- Testing
- Randomized to either a 'less tight' group or a 'tight' group
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Sunnybrook Health Sciences Centre
Blood Pressure
The Effects of Apple Derived Flavanols on Cardiovascular Disease Risk (FLAVASCULAR Study)
Fruit and vegetable rich diets are associated with a reduced risk of cardiovascular disease (CVD). The protective effect may be ascribed to compounds contained within these foods, called flavonoids.
- Trial name
- FLAVASCULAR (NCT02013856)
- Testing
- Low Epicatechin and procyanidin, High Epicatechin and procyanidin, High procyanidin
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Essential Hypertension
Safety Study of RMJH-111b to Treat Essential Hypertension
The purpose of this study was to evaluate the safety of RMJH-111b, including how well it is tolerated, and the effect of RMJH-111b on blood pressure in subjects with hypertension.
- Trial name
- NCT02822222
- Testing
- Magnesium citrate, tribasic anhydrous soft gelatin capsule
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- RMJ Holdings, LLC
Cardiovascular Diseases, Stroke Sequelae
Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility
Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity…
- Trial name
- NCT07420595
- Testing
- Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks)., Full 12 weeks CGT, progressing complexity and demands.
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Iqra National University
Hypertension
Electronic Communications and Home Blood Pressure Monitoring
The control of blood pressure (BP) for patients with hypertension on medications has been elusive, despite the availability of evidence-based nationally recognized guidelines for treatment and 30 years of research addressing…
- Trial name
- NCT00158639
- Testing
- Home BP;secure messaging;pharmaceutical care;
- Where
- United States
- Volunteers
- 778 people
- Sponsor
- Kaiser Permanente
Hypertension; Community Health Workers
Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda
Over 80% of the morbidity and mortality related to non-communicable diseases (NCDs) occurs in low-income and middle-income countries (LMICs).
- Trial name
- CHW-HTC (NCT05068505)
- Testing
- Community health worker delivered multicomponent intervention
- Where
- Uganda
- Volunteers
- 869 people
- Sponsor
- Charite University, Berlin, Germany
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