Clinical trials: Blood Pressure, completed
Cerebrovascular Disorders
Cost Effectiveness of the EndoPhys Pressure Sensing Access System vs. Radial A-line for Intra-operative Blood Pressure Monitoring
This study aims to compare the time difference between radial arterial line placement and use of the EndoPhys sheath, as well as, assess the cost effectiveness of the EnoPhys sheath vs.
- Trial name
- NCT03239847
- Testing
- EndoPhys Sheath and Radial Arterial Line, EndoPhys Sheath
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Hypertension
Health Literacy-Focused Program to Improve Blood Pressure Control in Korean Americans
Many Korean Americans are at risk for developing high blood pressure. Low health literacy levels may play a role in this risk. The purpose of this study is to evaluate a literacy-focused program aimed at reducing blood pressure…
- Trial name
- NCT00406614
- Testing
- Health Literacy-Focused High Blood Pressure Intervention
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Texas at Austin
Blood Pressure
Optical System to Continuously Measure Arterial Blood Pressure
Comparison of an optical method to continuously measure blood pressure against an invasive arterial catheter.
- Trial name
- BP (NCT02651558)
- Testing
- Experimental: OBPM 2015-MD-0022 - CHEST, Experimental: OBPM 2015-MD-0022 - CHEST & FINGER, Experimental: OBPM 2015-MD-0022 - FINGER
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement
Type 2 Diabetes
Study Looking at Cardiovascular Effects of Exenatide, Its Blood Pressure Lowering Effect and Its Mechanisms
Exenatide is a new drug which lowers blood sugar (glucose) levels for people with type 2 diabetes. It has significant advantages over other treatments such as insulin as it causes weight loss in a group of people that is…
- Trial name
- NCT01046721
- Testing
- Exenatide, Saline
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
General Anesthesia
Effect of Sevoflurane and Propofol on Hepato-splanchnic Pressure and Flow During Hepatobiliary Surgery
Blood loss in hepatobiliary surgery is correlated with an increase in postoperative complications (e.g. transfusion related lung injury and tumor recurrence) and reduced longterm survival.
- Trial name
- NCT03772106
- Testing
- Propofol Fresenius, sevorane
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- University Hospital, Ghent
Hypertension
Pharmacogenomic Evaluation of Antihypertensive Responses 2
There are many medications available for the treatment of high blood pressure (hypertension), but finding the right one for a specific patient can be challenging.
- Trial name
- PEAR2 (NCT01203852)
- Testing
- Metoprolol, Chlorthalidone
- Where
- 3 sites in United States
- Volunteers
- 839 people
- Sponsor
- University of Florida
Cardiovascular Risk Reduction
Young Hearts, Strong Starts
This is a cluster randomized trial of pediatric cardiovascular risk reduction guideline implementation in 32 clinical practices
- Trial name
- NCT01893593
- Testing
- Intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- RTI International
Hypertension,Essential, Obstructive Sleep Apnea
A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial Remodeling
The objective of this proposal is to evaluate whether mandibular advancement device (MAD) is non-inferior to continuous positive airway pressure (CPAP) in the treatment of obstructive sleep apnea (OSA) and blood pressure…
- Trial name
- CRESCENT (NCT04119999)
- Testing
- Mandibular Advancement Device, Continuous Positive Airway Pressure
- Where
- Singapore
- Volunteers
- 321 people
- Sponsor
- National University of Singapore
Healthy
Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT00912665
- Testing
- Laser Doppler Flowmetry, Goldmann applanation tonometer, squatting
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypertension
A Study to Investigate the Magnitude and Duration of Response of MK0954 Compared to Placebo in Patients With Hypertension (0954-021)(COMPLETED)
The purpose of this study was to evaluate the magnitude and durations of the antihypertensive effects of losartan using ambulatory blood pressure monitoring (ABPM), and to evaluate the safety of losartan 50 and 100 mg doses…
- Trial name
- NCT00886600
- Testing
- losartan potassium, hydrochlorothiazide (HCTZ)
- Volunteers
- 122 people
- Sponsor
- Merck Sharp & Dohme LLC
ESRD, Hemodialysis Complication
Timing of Antihypertensive Medications on Key Outcomes in Hemodialysis
For patients with kidney failure requiring hemodialysis treatment, sometimes the blood pressure will drop too low during dialysis.
- Conditions
- ESRD, Hemodialysis Complication, Blood Pressure
- Trial name
- TAKE-HOLD (NCT03327909)
- Testing
- TAKE vs. HOLD
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Stanford University
High-intensity Interval Exercise, Heart Rate
Acute Physiological and Perceptual Responses to Novel Forms of High-intensity Interval Exercise
Randomised cross-over study seeking to explore the acute physiological and perceptual responses to three novel forms of high-intensity interval training (HIT).
- Conditions
- High-intensity Interval Exercise, Heart Rate, Rating of Perceived Exertion, Blood Pressure
- Trial name
- NCT03359928
- Testing
- Boxing, Stair stepping, Stair climbing
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Teesside University
Glaucoma
Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data
To analyze Cosopt® in terms of its effects on ocular perfusion pressure and comprehensive ocular blood flow and in relation to visual field progression and optic nerve structural changes in an ongoing 3 year prospective study…
- Trial name
- NCT01145898
- Testing
- (Cosopt®, prostaglandin)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Cardiovascular Diseases, Heart Diseases
Longitudinal Studies of Blood Pressure in the Elderly
To study further the association between blood pressure mortality among those who participated in both the Hypertension Detection and Follow-up Program (HDFP) screen and the East Boston Established Populations for Epidemiologic…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005409
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Disease
Diet and Vascular Health Study
The aim of this study is to examine the effects of a diet rich in broccoli on cardiovascular disease risk using biochemical indicators such as blood lipid profiles, most notably cholesterol; markers of inflammation as well as…
- Trial name
- BROCCOLI (NCT01114399)
- Testing
- Diet and Vascular Health, Diet and Vascular Health Study
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Hypertension, Diabetes Mellitus Type 2
Effect of Pioglitazone on Ambulatory Blood Pressure
The anti-diabetic pioglitazone has been found to reduce casual blood pressure. To date, no data are available looking at this effect in detail.
- Trial name
- NCT00328393
- Testing
- Pioglitazone
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension
A Safety Evaluation of ECG Intervals and Blood Pressure in Normal Healthy Volunteers After Use of Nebivolol, Atenolol, Moxifloxacin, or Placebo
Nebivolol is one of a class of drugs known as beta-blockers. These drugs are useful in the treatment of high blood pressure, angina, abnormal heart rhythms and following a heart attack.
- Trial name
- NCT00158093
- Testing
- Nebivolol, Atenolol, Moxifloxacin
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Mylan Bertek Pharmaceuticals
Hypertension
Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil, once daily (QD), compared to ramipril for treating Essential Hypertension.
- Trial name
- NCT00760214
- Testing
- Azilsartan medoxomil, Ramipril
- Where
- 72 sites in Bulgaria, Estonia and 8 more
- Volunteers
- 885 people
- Sponsor
- Takeda
High Blood Pressure
Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation
Does dilation of blood vessels (vasodilation), which decreases aortic stiffness, have a greater effect on heart myocardium relaxation (diastole) than vasodilation which affects mean pressure equally without improving aortic…
- Trial name
- NCT00204984
- Testing
- oral hydralazine and intravenous nesiritide
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sepsis, Norepinephrine
Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:
The aim of our study is to compare between transcranial doppler pulsatility index and mean arterial blood pressure in guiding management of sepsis induced encephalopathy.
- Conditions
- Sepsis, Norepinephrine, Encephalopathy
- Trial name
- NCT05842616
- Testing
- Transcranial doppler pulsatility index guided protocol, Mean arterial blood pressure guided protocol
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Tanta University
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