Clinical trials: Blood Pressure Control
Positive Emotions, Blood Pressure
The Impact of a Gratitude Intervention on Stress Reactivity
This study will employ a randomized mixed between-within experimental stress-testing protocol design. Physiological responses (blood pressure and pulse) will be recorded throughout a baseline, gratitude induction, standard…
- Conditions
- Positive Emotions, Blood Pressure, Stress, Psychological
- Trial name
- NCT05133063
- Testing
- Gratitude letter, Control intervention
- Where
- Ireland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Maynooth
Healthy
A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State
The primary purpose of this study is to evaluate the effect of the up-titration regimen of ponesimod on heart rate (HR) and other electrocardiogram (ECG) parameters when administrated to healthy adult participants receiving…
- Trial name
- NCT03882255
- Testing
- Ponesimod dose range (2 - 20 mg), Propranolol 80 mg
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Cardiovascular Disease
Acute Effects of Ginger Extract Consumption on Risk Markers of Cardiovascular Disease
The primary aim of the study was to investigate the acute effect of ginger drink consumption on the risk markers of cardiovascular disease.
- Trial name
- G-CVD (NCT02735486)
- Testing
- Ginger drink
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Reading
25-hydroxyvitamin D Concentration (Vitamin D Status)
D-Light Intervention
Vitamin D insufficiency has become a global concern, with low vitamin D status associated with bone disorders, cardiovascular disease and certain cancers.
- Trial name
- D-Light (NCT02495584)
- Testing
- Fortified milk (10µg vitamin D3), 10µg vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Arterial Pressure, Blood Pressure Determination
Standardized Patients in Arterial Pressure Monitoring Training
This study aims to evaluate and compare the effects of using standardized patients versus static manikins in nursing education for arterial blood pressure monitoring and stabilization training.
- Conditions
- Arterial Pressure, Blood Pressure Determination, Simulation Training, Education, Nursing
- Trial name
- NCT07670364
- Testing
- Arterial Pressure Monitoring Training
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Sodium, Renal Function
The Effect of Sodium on Erythrocyte Salt Sensitivity, Syndecan-1 and Heparin Sulfate in Healthy Subjects.
The study was a double-blinded, randomized, placebo-controlled cross-over study. 27 healthy subjects received a four days standardized, sodium reduced diet (100 mmol sodium) and treatment with sodium chloride (200 mmol sodium) or…
- Conditions
- Sodium, Renal Function, Blood Pressure
- Trial name
- EGNA (NCT06968182)
- Testing
- Sodium Chloride
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Frank Mose
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension
Effects of Transcutaneous Vagal Nerve Stimulation on Hemodynamics Parameters
The vagal stimulation is a promising therapy for a lot of disorders as well as hemodynamic regulatory way. In order to minimize the harm of a surgery chip implantation, actually it was developing a non-invasive device that is…
- Trial name
- NCT03000842
- Testing
- transcutaneous vagal nerve stimulation on, transcutaneous vagal nerve stimulation off
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hypotension, Spinal Cord Injury
Prevention of Low Blood Pressure in Persons With Tetraplegia
The aim of this investigation is to determine the blood pressure response to NOS inhibition, with L-NAME, in persons with tetraplegia compared to non-SCI control subjects and to establish if blood pressure can be increased while…
- Trial name
- NCT00237770
- Testing
- N-Nitro L-arginine-methylester (L-NAME), Head-up Tilt maneuver
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Blood Pressure, Heart Rate and Rhythm Disorders
Acute Maternal and Fetal Effects of Exercise in Pregnancy
This will be an open randomized clinical trial involving pregnant women between 35 and 37 weeks randomized to two modalities of exercise: treadmill or stationary bike.
- Conditions
- Blood Pressure, Heart Rate and Rhythm Disorders, Hypoglycemia, Lactate
- Trial name
- EXPREG (NCT01383889)
- Testing
- Physical exercise
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Cardiovascular Risk Factors
Beneficial Impact of Orange Juice Consumption on Risk Factors Associated With Cardiovascular Diseases
The primary aim is to examine both the acute and chronic effects of hesperidin consumption from 100% Florida orange juice in various doses on functional and systemic markers associated with cardiovascular disease (CVD) risks.
- Trial name
- CITRUS (NCT02479568)
- Testing
- Control, 100% Florida OJ, 100% Florida OJ-enriched
- Where
- Spain
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Sarcopenia, Hypertension
Effects of Variable Load Exercise on Aging Atrophy
The primary aim of this research proposal is to examine whether this novel training program approach is capable to tackle excessive loss in muscle mass, function and contractile capacity with aging.
- Conditions
- Sarcopenia, Hypertension, Muscle Atrophy
- Trial name
- NCT03690258
- Testing
- Variable load exercise
- Where
- 2 sites in Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Split
Healthy Volunteers, Cardiovascular System
Effects of Transcutaneous Electrical Stimulation on the Autonomous Nerve System in Healthy Young People
Cardiovascular disease is one of the most important causes of death and disability in the world. An autonomic imbalance is associated to cardiovascular risks and disorders.
- Conditions
- Healthy Volunteers, Cardiovascular System, Autonomic Nervous System
- Trial name
- ESautonomous (NCT05289817)
- Testing
- Transcutaneous Vagus Nerve Stimulation (t-VNS), Transcutaneous Sympathetic Ganglion Electrical Stimulation (t-SES)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Blood Pressure, Cardiovascular Diseases
SRMA of the Effect of Soy Protein on Blood Pressure
Hypertension is one of the leading risk factors for death and significantly increases the risk for cardiovascular (CVD), brain and kidney diseases.
- Trial name
- NCT05638061
- Testing
- Soy protein
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Overweight
Effect of Calcium/Vitamin D Supplementation on Body Weight and Fat Loss.
The aim of this study was to assess the effect of calcium/vitamin D supplementation (Caltrate 600 +D®) on body weight loss during a weight-reducing program
- Trial name
- NCT00353054
- Testing
- Caltrate® 600 + D, Weight loss intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laval University
Vascular Stiffness, Blood Pressure
Magnesium and Vascular Stiffness
This four-arm randomized controlled trial was designed to study the effects of magnesium supplements (total daily dose: 450 mg elemental magnesium) on vascular stiffness in healthy overweight and slightly obese men and women.
- Trial name
- NCT03632590
- Testing
- Magnesium Citrate, Magnesium Sulfate, Magnesium Oxide
- Where
- Netherlands
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Blood Pressure
A Two-part Trial Assessing the Effects of 7α-methyl-19-nortestosterone (MENT) on Blood Pressure in Normal Men: an Open-label Pilot Study Followed by a Randomized, Double-blind, Placebo-controlled Study
This is a two-part trial assessing the effects of MENT on blood pressure. The first part of the trial is an open-label pilot study to verify the MENT gel formulation delivers appropriate drug levels.
- Trial name
- NCT00812630
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Population Council
Pain, Anxiety
The Use of Music for Pain and Anxiety Control During Abortion
Most first trimester abortions are performed under local anesthesia using either manual or electric vacuum suction aspiration. The majority of women undergoing these procedures experience some amount of pain and anxiety.
- Trial name
- NCT01013363
- Testing
- iPod Nano digital music player
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Uncontrolled Hypertension, Treatment Compliance
Integrative Nursing Based Multimodal Interventions for Uncontrolled Hypertensives
Purpose: The aim of this study is to evaluate the effect of multimodal interventions based on Integrative Nursing (IN) principles on blood pressure, stress, and hypertensive treatment compliance levels in individuals living in…
- Conditions
- Uncontrolled Hypertension, Treatment Compliance, Behavior, Health, Nurse's Role
- Trial name
- UHTINuM (NCT04809519)
- Testing
- Integrative Nursing based Multimodal Interventions for Uncontrolled Hypertensives, Ongoing treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hypertension
Effects of NSK-SD (Nattokinase) on Blood Pressure
This is a randomized double-blinded placebo-controlled study to evaluate the effects of NSK-SD consumption in subjects with Stage I hypertension.
- Trial name
- NCT02886507
- Testing
- NSK-SD (nattokinase)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc