Clinical trials: Blood Pressures
Hypertension
A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009)
This study is being done to evaluate the antihypertensive efficacy and tolerability of MK-7145 in participants with mild-to-moderate hypertension. The primary hypotheses for the study were as follows: 1.
- Trial name
- NCT01370655
- Testing
- MK-7145, Hydrochlorothiazide (HCTZ)
- Volunteers
- 46 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension, Diabetes Mellitus, Type 2
SMOOTH - Blood Pressure Control in Diabetic/Obese Patients
The primary objective of this study is to demonstrate that telmisartan 80 mg combined with hydrochlorothiazide 12.5 mg (T80/H12.5) is at least as effective and possibly superior to valsartan 160 mg combined with…
- Trial name
- NCT00239538
- Testing
- telmisartan combined with hydrochlorothiazide (80/12.5 mg), valsartan combined with hydrochlorothiazide (160/12.5mg)
- Where
- 102 sites in United States, Argentina and 6 more
- Volunteers
- 840 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Arterial Hypertension
A Study to Learn About How Well Riociguat Works, How Safe it is and How it is Used Under Real World Conditions in Patients in the United States Who Are Receiving Riociguat for High Blood Pressure in the Arteries That Carry Blood From the Heart to the Lungs (Pulmonary Arterial Hypertension, PAH)
Pulmonary arterial hypertension (PAH) is a type of high blood pressure in the arteries that carry blood from the heart to the lungs. PAH occurs when the openings in the blood vessels of the lungs get smaller and smaller.
- Trial name
- ROAR (NCT04813926)
- Testing
- Riociguat (Adempas, BAY63-2521)
- Where
- 50 sites in United States, Puerto Rico
- Volunteers
- 500 people
- Sponsor
- Bayer
Hypertension, Congestive Heart Failure
To Evaluate the Efficacy and Safety on Blood Pressure In Patients With Hypertension Diagnosed Congestive Heart Failure
To compare and evaluate the efficacy and safety of Candemore tab. versus Atacand tab. on blood pressure in patients with hypertension diagnosed congestive heart failure
- Trial name
- CANTABILE (NCT01682564)
- Testing
- Candemore tablet, Atacand tablet
- Where
- 14 sites in South Korea
- Volunteers
- 169 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Blood Pressure
ModPG3 Adult/Ped ISO 81060-2:2018 Study Protocol
Automated blood pressure cuff measurements taken by an "oscillometric device" is the standard in numerous medical settings today.
- Trial name
- NCT05654714
- Testing
- ModPG3 Investigational Device, Auscultatory Equipment
- Where
- Italy
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Welch Allyn
Resistant Hypertension
A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension
This is a Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety, tolerability and the effect of 2 mg Baxdrostat vs.
- Trial name
- Bax24 (NCT06168409)
- Testing
- Baxdrostat
- Where
- 102 sites in United States, Argentina and 20 more
- Volunteers
- 218 people
- Sponsor
- AstraZeneca
Blood Pressure
Polso™ Watch Blood Pressure Accuracy With Blood Pressure Change Validation
Up to 185 adult test subjects to evaluate blood pressure measurement accuracy and stability of the Polso™ Watch compared to a reference blood pressure measurement.
- Trial name
- BP (NCT05735210)
- Testing
- Polso™ Watch blood pressure measurement compared to a reference blood pressure measurement
- Where
- Germany
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- ChroniSense Medical Ltd.
Mild Hypertension
A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor Administered Subcutaneously to Hypertensive Participants With Controlled Blood Pressure
This was a Phase 2, double-blind, randomized, placebo-controlled study of IONIS-AGT-LRx conducted in mild hypertensive participants.
- Trial name
- NCT03714776
- Testing
- ISIS 757456
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Blood Pressure
A-line/CareTaker Comparison Study in ICU Patients
Comparison of Blood Pressures obtained with the Pulse Decomposition Algorithm and Intra-Arterial Catheters in ICU Patients
- Trial name
- NCT02479724
- Testing
- continuous non-invasive blood pressure monitor
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Empirical Technologies Corporation
Atrial Fibrillation, Arrhythmias, Cardiac
Validation Study of WITHINGS BPM Core for the Detection of Atrial Fibrillation
The proposed clinical study aims to validate the diagnostic performance, compared to a reference ECG, of the electrocardiographic function of the BPM Core developed by Withings for the automatic identification of atrial…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- Core AF (NCT04464499)
- Testing
- ECG measurement
- Where
- 2 sites in France
- Volunteers
- 160 people
- Sponsor
- Withings
Hyperkalemia, Resistant Hypertension
Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease
The purpose of this study is to determine if patiromer treatment in chronic kidney disease (CKD) subjects receiving spironolactone for the treatment of resistant hypertension will result in more persistent use of spironolactone…
- Trial name
- AMBER (NCT03071263)
- Testing
- Patiromer, Spironolactone
- Where
- 40 sites in United States, Bulgaria and 7 more
- Volunteers
- 295 people
- Sponsor
- Relypsa, Inc.
Compartment Syndrome
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
An investigation of a new catheter and pressure monitor system that may help to prevent a complication called compartment syndrome from developing in an injured leg.
- Trial name
- TS2 (NCT00681616)
- Testing
- Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
- Where
- 13 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Twin Star Medical, Inc.
Hypertension
The Effect of Grape Seed Extract on Blood Pressure in People With Pre-Hypertension
In this research study, the investigators are interested in learning how extracts from grape seeds can help those individuals with high blood pressure.
- Trial name
- GSE (NCT00979732)
- Testing
- grape seed extract
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Atrial Fibrillation, Rhythm; Disorder
REmote CArdiac MOnitoring by the Corsano CardioWatch 287-2 Evaluation Study
In this study, a wristband that monitors hearth rhythm and blood pressure is assessed in free living conditions. Two groups of patients are being recruited: patients receiving an EKG holter and patients receiving an automatic…
- Conditions
- Atrial Fibrillation, Rhythm; Disorder, Palpitations, Hypertension
- Trial name
- RECAMO (NCT05899959)
- Testing
- Corsano CardioWatch 287-2
- Where
- Netherlands
- Volunteers
- 190 people
- Sponsor
- Corsano Health B.V.
Hypertension
Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker
A comparison of 2 different combinations of high blood pressure medications to treat hypertension
- Trial name
- NCT00185120
- Testing
- Olmesartan medoxomil, Hydroclorothiazide, Benazepril
- Where
- 20 sites in United States
- Volunteers
- 152 people
- Sponsor
- Daiichi Sankyo
Hypertension
Rheos® Pivotal Trial
The purpose of this clinical trial is to demonstrate the efficacy and safety of the Rheos system in subjects with hypertension that are resistant to treatment with at least three anti-hypertension agents, one of which is a…
- Trial name
- NCT00442286
- Testing
- Rheos® Baroreflex Hypertension System
- Where
- 44 sites in United States, Germany and 1 more
- Volunteers
- 591 people
- Sponsor
- CVRx, Inc.
Hypertension
A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic blood pressure in participants with mild to moderate hypertension in addition to safety and tolerability.
- Trial name
- NCT01446003
- Testing
- MK-8457
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
Study to Evaluate Efficacy of Micardis® (Telmisartan) and Valsartan in Patients With Mild-to-moderate Hypertension After Missing One Dose Using Ambulatory Blood Pressure Monitoring
The primary aim of the trial is to compare telmisartan 80 mg to valsartan 160 mg in lowering diastolic blood pressure in patients who missed a dose of their medication, as measured by ABPM (change from baseline in mean DBP over…
- Trial name
- NCT02242318
- Testing
- Telmisartan, Valsartan
- Volunteers
- 440 people
- Sponsor
- Boehringer Ingelheim
Hypertension
OBPM_Meds2023: Multicentric Prospective Clinical Study to Evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) Device Compared to Standard Home Blood Pressure Monitoring (HBPM) in Hypertensive Patients When Blood Pressure Lowering Medications Intake
Study design: Prospective, multicentric, randomized, comparative study Study duration: between 4 and 19 weeks depending on the study group.
- Trial name
- OBPM_Meds2023 (NCT05780710)
- Testing
- Aktiia Optical Blood Pressure Monitoring (OBPM) device and antihypertensive drugs (monotherapy and bitherapy), Aktiia Optical Blood Pressure Monitoring (OBPM) device and antihypertensive drugs (monotherapy), Aktiia Optical Blood Pressure Monitoring (OBPM) device and individualized antihypertensive treatment
- Where
- 3 sites in Switzerland
- Volunteers
- 35 people
- Sponsor
- Aktiia SA
Blood Pressure
Fresenius Noninvasive Blood Pressure Validation
The purpose of this study to collect blood pressure measurement values from the blood pressure measurement device on the Fresenius machine as compared to the standard method.
- Trial name
- BPM2 (NCT04573595)
- Testing
- Blood Pressure Measurement
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Fresenius Medical Care North America