Clinical trials: Blood Pressures
Essential Hypertension
Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil combined with chlorthalidone, once daily (QD), in participants with moderate to severe essential hypertension.
- Trial name
- NCT00846365
- Testing
- Azilsartan medoxomil and chlorthalidone, Olmesartan medoxomil-hydrochlorothiazide
- Where
- 80 sites in United States, Chile and 1 more
- Volunteers
- 1,085 people
- Sponsor
- Takeda
Heart Disease
Postprandial Hemodynamics
To study the postprandial alterations in hemodynamics and blood pressure in relation to gastric emptying rate, postprandial blood glucose, plasma concentrations of insulin, satiety in healthy subjects.
- Trial name
- NCT01027507
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Hypertension
Effects of a Resistance Training Period on Blood Pressure of Hypertensive Elderlies: Influence of the Polymorphism of the Angiotensin Converting Enzyme
The study aimed to evaluate the chronic effects of resistance training on blood pressure and biochemical exams in hypertensive elderlies and the influence of the polymorphism of the angiotensin converting enzyme in these response.
- Trial name
- NCT01963507
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- Federal University of São Paulo
Cardiovascular Diseases
Tight Closed-loop Systolic Arterial Pressure Control
The purpose of this case series is to evaluate the performance of a novel closed-loop (automated) vasopressor administration system that delivers norepinephrine using feedback from standard operating room hemodynamic monitoring…
- Trial name
- NCT04357301
- Testing
- Closed-loop vasopressor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Erasme University Hospital
Transgender, Gender Identity
The Effects of Orchiectomy and Age on Vascular and Metabolic Health in Older Versus Younger Transgender Women
This study plans to learn more about differences in heart disease risk after gender-affirming orchiectomy (i.e., testes removal) in older transgender (trans) women compared to younger trans women.
- Conditions
- Transgender, Gender Identity, Vascular Stiffness, Vascular Inflammation
- Trial name
- NCT05195164
- Testing
- No intervention
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypertension
Assessing Alternative Approaches for Blood Pressure Control: A3BC Trial
An estimated 76 million adults in the United States over the age of 20 have hypertension (HTN); which translates into 1 out of 3 adults.
- Trial name
- NCT02110381
- Testing
- Device guided breathing RESPeRATE, Isometric hand grip Zona Plus
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Prehypertension
Diet and Exercise on Ambulatory Blood Pressure
This is a multicenter, randomized, single-blinded clinical trial investigating the effect of dietary management and active aerobic exercise training on reduction of 24-hour ambulatory blood pressure in subjects with…
- Trial name
- NCT05274971
- Testing
- Active dietary management and aerobic exercise training.
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Metabolic Disease, Insulin Sensitivity
Metabolic Effects of Melatonin Treatment
Modern living is associated with an epidemic of type 2 diabetes mellitus (T2DM). Sleep disturbances such as insomnia or frequent awakenings are strong risk factors for T2DM with several studies indicating a central role of…
- Conditions
- Metabolic Disease, Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus), Type 2 Diabetes Mellitus
- Trial name
- NCT03859934
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Left Ventricular Hypertrophy
Effects Of Volume Control Guided by Body Composition Monitor (BCM) on Blood Pressure and Cardiac Condition in Hemodialysis Patients
This prospective, randomized, controlled study aims to evaluate the usefulness of the new body composition monitor (BCM) device as a method to improve volume control in hemodialysis (HD) patients and compare the results with…
- Trial name
- NCT00974857
- Testing
- BCM, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ege University
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hemodynamics Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.
- Conditions
- Hemodynamics Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- PH (NCT03861364)
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Helse Fonna
Hypertension
Groceries for Black Residents of Boston to Stop Hypertension Among Adults With Treated Hypertension
GoFreshRx is a randomized trial, testing the effects of a home-delivered DASH-patterned grocery intervention on blood pressure in Black adults actively treated for hypertension, residing in Boston area urban food deserts.
- Trial name
- GoFreshRx (NCT05393232)
- Testing
- Dietitian-Assisted DASH groceries, Self-directed shopping
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Beth Israel Deaconess Medical Center
High Blood Sugar, High Blood Pressure
Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides.
- Conditions
- High Blood Sugar, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT06555393
- Testing
- Egg White Powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hypotension
Early Prediction of ICU Hypotension Using Machine Learning
This prospective observational study aims to develop and internally validate a machine learning model for the early prediction of hypotension in adult intensive care unit patients.
- Trial name
- ICU-HypoAI (NCT07627607)
- Testing
- Routine ICU Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University
Type 2 Diabetes, Coronary Artery Disease
Intensive Blood Pressure and LDL Lowering in Diabetic Patients With Coronary Artery Disease
The purpose of this study is to determine whether intensive blood pressure and low density lipoprotein (LDL) cholesterol lowering could improve survival and cardiovascular outcome in Japanese diabetic patients with coronary…
- Conditions
- Type 2 Diabetes, Coronary Artery Disease, Hypertension, Dyslipidemia
- Trial name
- NCT01422421
- Testing
- intensive control, standard control
- Where
- 2 sites in Japan
- Volunteers
- 798 people
- Sponsor
- Takeshi Morimoto
Hypertension
Efficacy of a Natural Ingredient on Blood Pressure
Randomized controlled trial with two parallel branches (experimental product and placebo), double blind and unicentric with which it is intended to evaluate the efficacy of the product under investigation against placebo on blood…
- Trial name
- FISTA (NCT03471533)
- Testing
- nutraceutical: experimental product
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Renal Dialysis
The Effect of Food Intake During Hemodialysis on Blood Pressure
Intradialytic hypotension is one of the most common complications associated with food intake during hemodialysis. Whether patients should be allowed to eat during hemodialysis is still a moot point.
- Trial name
- NCT05405348
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- melek avcı
Prematurity of Fetus
Effect of Prematurity on Renal Function in 5 Years Old Children
Purpose of the study: 1. To evaluate the effect of prematurity on renal function in 5 years old children 2. To compare former premature children treated by ibuprofen in the neonatal period to controls
- Trial name
- SUIVIREIN (NCT00817921)
- Where
- 3 sites in France
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Jean Michel Hascoet
Metabolic Syndrome
A New Supplement for the "Metabolic Syndrome"
This study evaluates the effect of a combination of glycirrhizic acid, Cinnamomun Zeylanicum and corosolic acid for the treatment of metabolic syndrome. Participants receive the supplement or a placebo.
- Trial name
- NCT03813914
- Testing
- Sineos
- Volunteers
- 60 people
- Sponsor
- University of Messina
Mild to Moderate Hypertension
A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension
The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacodynamics (PD) and pharmacokinetics (PK) of zilebesiran in Japanese patients with mild to moderate hypertension.
- Trial name
- NCT06423352
- Testing
- Zilebesiran
- Where
- 3 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Alnylam Pharmaceuticals
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