Clinical trials: Blood Pressures
Hypertension
Effects of NSK-SD (Nattokinase) on Blood Pressure
This is a randomized double-blinded placebo-controlled study to evaluate the effects of NSK-SD consumption in subjects with Stage I hypertension.
- Trial name
- NCT02886507
- Testing
- NSK-SD (nattokinase)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Spinal Cord Injury
Bowel Care and Cardiovascular Function After Spinal Cord Injury
The main goal of this project is to determine the effects of lidocaine lubricant on cardiovascular function during routine bowel care in individuals with spinal cord injury.
- Trial name
- NCT01567605
- Testing
- Lidocaine lubricant
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Simon Fraser University
Hypertension
A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide.
Assessment of the long-term safety and tolerability of the combination of aliskiren and valsartan (300 mg/ 320 mg) in patients with high blood pressure,followed by assessment of long-term safety and tolerability of the…
- Trial name
- NCT00386607
- Testing
- Aliskiren, Valsartan, Hydrochlorothiazide (HCTZ)
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 601 people
- Sponsor
- Novartis
Hypertension
Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study
The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood pressure).
- Trial name
- NCT01009944
- Testing
- Lisinopril, Atenolol
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Injections, Intravenous
Comparison of Perfusion Index, T Wave Amplitude, Systolic Blood Pressure and Heart Rate
The purpose of this study is to determine whether changes in perfusion index can be used for detecting intravascular injection of an epinephrine in anesthetized adults and to compare its reliability with criteria using changes in…
- Trial name
- NCT01131741
- Testing
- Epinephrine, Control
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Hypertension, Cardiovascular Disease
Socioeconomic Status, Psychosocial Factors, and CVD Risk in Mexican-American Women
Cardiovascular disease (CVD) is the leading cause of death in American women, claiming on average 40% of all female deaths each year.
- Conditions
- Hypertension, Cardiovascular Disease, Metabolic Disorders
- Trial name
- NCT00387166
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Otherwise Healthy Individuals With Systolic Blood Pressure (SBP) From 110 to 139 mmHg and Low-density Lipoprotein Cholesterol (LDL-C) ≥ 100 mg/dL
A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers
This clinical trial has two parts. In Part A, the goal is to learn about the safety and tolerability of COR-2003 when it is given alone.
- Trial name
- NCT07858019
- Testing
- COR-2003, COR-1004 + COR-2003
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Corsera Health
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Hypertension
Study of the Impact of Low Fat Dairy and High Fat Dairy Consumption on Daytime Ambulatory Blood Pressure
Market trends depicted by Agriculture and Agri-Food Canada suggest stagnation in cheese consumption, with potentially important impact on this key industry in Canada.
- Trial name
- GABA2 (NCT02763930)
- Testing
- Control diet, Milk diet, GABA-rich cheese diet
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
General Anesthetics
Changes in Autonomic Nervous Activity and Blood Pressure After Anesthesia Induction: Remimazolam Versus Propofol
The goal of this clinical trial is to compare the effects of changes in autonomic nervous activity on changes in blood pressure after anesthesia induction between propofol and remimazolam in patients undergoing low-risk surgery.
- Trial name
- NCT05635201
- Testing
- Anesthesia induction with propofol, Anesthesia induction with remimazolam
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Daegu Catholic University Medical Center
Essential Hypertension
NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial
In this Phase III clinical trial, researchers evaluate the efficacy and safety of NW Roselle®, a powdered medicinal product developed by Natural Wellness.
- Trial name
- NCT06141200
- Testing
- NW Roselle, Captopril 25Mg Tab
- Volunteers
- 286 people
- Sponsor
- Natural Wellness Egypt
Hypertension
Assessing Alternative Approaches for Blood Pressure Control: A3BC Trial
An estimated 76 million adults in the United States over the age of 20 have hypertension (HTN); which translates into 1 out of 3 adults.
- Trial name
- NCT02110381
- Testing
- Device guided breathing RESPeRATE, Isometric hand grip Zona Plus
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Food Insecurity, Dietary Quality
Enjoying Affordable and Tasty Food Together
The goal of this pilot study is to examine the feasibility of a novel meal kit and nutrition education intervention among adults aged 40 years and older, who are lower income, and to evaluate the preliminary impact of the meal…
- Conditions
- Food Insecurity, Dietary Quality, Quality of Life, Cooking Self-efficacy
- Trial name
- PROJECT EATT (NCT07036757)
- Testing
- Meal Kit and Nutrition Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Massachusetts, Lowell
Diabetes Mellitus Type 2 (T2DM)
Empagliflozin as a Modulator of Systemic Vascular Resistance and Cardiac Output in Patients With Type 2 Diabetes
SGLT2 inhibitors are a novel class of glucose lowering drugs that act in the kidney by inhibiting SGLT2-mediated glucose reabsorption in the proximal tubule.
- Trial name
- EMPA (NCT03132181)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- RWTH Aachen University
Blood Pressure
Clinical Evaluation of the Performance of Bionet Sphygmomanometer Modules Based on Protocol Presented by the International Organization for Standardization
According to INTERNATIONAL STANDARD (hereafter ISO) blood pressure (BP) monitor clinical evaluation protocol (ISO 81060-2:2018, Non-invasive sphygmomanometers- Part2: Clinical investigation of intermittent automated measurement…
- Trial name
- NCT06609486
- Testing
- Blood pressure measurement group
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hoon-Ki Park
PreDiabetes
MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes
One in three American adults have prediabetes, and up to 70% of adults with prediabetes eventually develop type 2 diabetes. With the high cost of treating diabetes, cost-effective approaches are needed to reduce the incidence of…
- Trial name
- NCT03504683
- Testing
- Early TRE, Mid-day TRE, Control Schedule
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Hypertension
A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With Hypertension
This was the first evaluation of the effects of LCZ696 on local and regional measures of aortic stiffness in subjects with mild to moderate hypertension and widened pulse pressure.
- Trial name
- NCT01870739
- Testing
- sacubitril/valsartan (LCZ696), olmesartan, Amlodipine (Optional)
- Where
- 4 sites in Germany, Switzerland and 1 more
- Volunteers
- 115 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Effects of Inspiratory Muscle Training on Blood Pressure Levels in Hypertensive Individuals
This research aims to evaluate the effects of inspiratory muscle training (IMT) on blood pressure, in inspiratory muscle mechanoreflex, autonomic cardiovascular control in subjects with hypertension.
- Trial name
- NCT02275377
- Testing
- Inspiratory muscle training (IMT)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiovascular Risk Factor, Heat Stress
Exercise and Sauna on Blood Pressure and Cardiovascular Health
The study aims to investigate the effects of including regular heat therapy when included to exercise. Specifically, participants in the sauna intervention group will undergo 15 minutes of sauna exposure immediately after a…
- Conditions
- Cardiovascular Risk Factor, Heat Stress, Sedentary Behavior
- Trial name
- ES2019 (NCT04540718)
- Testing
- Exercise, Sauna
- Where
- Finland
- Volunteers
- 47 people
- Sponsor
- University of Jyvaskyla
Pulmonary Disease, Chronic Obstructive
Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions
The aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.
- Trial name
- NCT00295113
- Testing
- EFR
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Strasbourg, France
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