Clinical trials: Blood Pressures
Atrial Fibrillation (AF), Hypertension (HTN)
Out-of-office Monitoring for Rhythms Of Normal Versus Atrial Fibrillation
The goal of this clinical trial is to learn if screening for atrial fibrillation (AFib), a common irregular heart rhythm, through daily home blood pressure monitoring will decrease the time to atrial fibrillation diagnosis in…
- Conditions
- Atrial Fibrillation (AF), Hypertension (HTN), High Blood Pressure
- Trial name
- OMRON-AF (NCT07582523)
- Testing
- Blood Pressure Monitor Without AFib Detection, Blood Pressure Monitor With AFib Detection
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- University of California, San Francisco
Treatment Adherence and Compliance
A Factorial Approach to Improve Treatment Adherence and Systolic Blood Pressure
In Pakistan, poor medication adherence is a key operational factor in the prevalence of uncontrolled hypertension. Mobile phone treatments based on technology are at the forefront and are a reasonably low-cost strategy for…
- Trial name
- NCT05106790
- Testing
- Educational support with peer counseling, mHealth intervention, mHealth intervention and Educational support with peer counseling
- Where
- 6 sites in Pakistan
- Volunteers
- 1,440 people
- Sponsor
- Universiti Putra Malaysia
HIV/AIDS, Hypertension
Integration of Hypertension Management in HIV Care in Uganda
Effective, cost-effective, scalable, sustainable, and equitable implementation strategies to improve care for people living with HIV and co-morbid hypertension in sub-Saharan Africa are urgently needed.
- Trial name
- PULESAUganda (NCT05609513)
- Testing
- HTN-BASIC, HTN-PLUS
- Where
- 16 sites in Uganda
- Volunteers
- 87,421 people
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Cardiovascular Disease, High Blood Pressure
Using Practice Facilitation in Primary Care Settings to Reduce Risk Factors for Cardiovascular Disease
The primary purpose of this study is to evaluate the effectiveness of practice facilitation as a quality improvement strategy for implementing the Million Hearts' ABCS treatment guidelines for reducing cardiovascular disease…
- Trial name
- NCT02646488
- Testing
- Million Hearts ABCS 6 Months, Million Hearts ABCS 9 Months, Million Hearts ABCS 12 Months
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- NYU Langone Health
Intraocular Pressure Changes During Tracheal Extubation
Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade
The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation.
- Trial name
- NCT02215382
- Testing
- sugammadex, neostigmine+atropine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ordu University
High Altitude Pulmonary Hypertension
Highlanders With High Altitude Pulmonary Hypertension (HAPH), Pulmonary Arterial Pressure (PAP) Assessed at 3200m With and Without Supplemental Oxygen Therapy (SOT)
The investigators aim to study the effect of SOT in highlanders with high altitude pulmonary hypertension (HAPH) who permanently live >2500m on pulmonary arterial pressure (PAP) assessed at 3200 m.
- Trial name
- NCT06489756
- Testing
- Echocardiography
- Where
- Kyrgyzstan
- Volunteers
- 48 people
- Sponsor
- University of Zurich
Hypertension
The Evaluation and Standardization of Ginseng and Its Components for Blood Pressure Regulation
While the use of herbals is increasing considerably, their efficacy and safety in the humans remains largely unknown. This surge in demand prompts a call for its evaluation.
- Trial name
- NCT00730951
- Testing
- Korean Red Ginseng, Corn Starch
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Unity Health Toronto
Healthy Aging
Race and Socioeconomic Position: Examining Common Social Pathways to Disease Risk
Black Americans and those of lower socioeconomic position (SEP) are at higher risk for multiple diseases of aging and shorter lifespans, but the psychophysiological mechanisms that may account for these effects are not clear.
- Trial name
- NCT06552702
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Alabama, Tuscaloosa
Hypertension,Essential, Hypertension
Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People
Introduction: Adequate blood pressure control is necessary to reduce the risk of mortality from cardiovascular events. The effects of aerobic exercise on systemic arterial hypertension are already well known, however, to date…
- Trial name
- NCT06282302
- Testing
- Group control, Isometric Exercise, Aerobic Exercise
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Gestational Hypertension, Preeclampsia (PE)
Postpartum CO Rehabilitation
Some women who develop high blood pressure during pregnancy, such as gestational hypertension or preeclampsia, may continue to have slightly or moderately high blood pressure after giving birth.
- Trial name
- NCT06920537
- Testing
- Postpartum Cardio-obstetric Rehabilitation Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Heart Failure With Preserved Ejection Fraction (HFpEF), Hypertension
Study for the Treatment of Heart Failure With Preserved Ejection Fraction Associated With High Blood Pressure Using Right Atrial Pacing Controlled by the PressurePaceTM System
This study is a prospective, double blind, self-controlled, randomized, cross-over study to evaluate the feasibility, efficacy, and safety of treating patients with Heart Failure with preserved Ejection Fraction (HFpEF)…
- Trial name
- RelieveHFpEFII (NCT06036186)
- Testing
- BaroPacing treatment, Standard treatment
- Where
- 3 sites in India
- Volunteers
- 16 people
- Sponsor
- BaroPace Inc.
Metabolic Syndrome
Assessing The Treatment Effect in Metabolic Syndrome Without Perceptible diabeTes (ATTEMPT)
The objective of this protocol is to improve awareness, treatment, and control of metabolic syndrome, within primary prevention of cardiovascular disease, by implementing guidelines, after training of the participating physicians.
- Trial name
- ATTEMPT (NCT00416741)
- Testing
- Implementation of guidelines
- Where
- Greece
- Volunteers
- 2,000 people
- Sponsor
- Hellenic Atherosclerosis Society
Blood Pressure, Inflammation
Community-Engaged Research: A Tool to Advance Cookstove Interventions
Nearly 3 billion people rely on biomass combustion to meet basic domestic energy needs. Many households use traditional cookstoves to meet these energy needs, which can result in extremely high indoor air pollution…
- Conditions
- Blood Pressure, Inflammation, Glycated Hemoglobin (HbA1c)
- Trial name
- NCT02658383
- Testing
- Cleaner cookstove received after visit 2, Cleaner cookstove received after visit 4
- Where
- Honduras
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Sleep Deprivation
Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period
Short sleep duration confers high cardiovascular and metabolic risk, but lifestyle factors and molecular mechanisms that contribute to increased blood pressure and poor glucose control during short sleep are not completely…
- Trial name
- CRISP (NCT06070194)
- Testing
- Time restricted eating (TRE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hypertension
Efficacy/Safety of Valsartan Plus Amlodipine and Valsartan Alone in Patients With Hypertension
This study evaluated the safety and efficacy of the fixed combination of valsartan/amlodipine in adult patients with mild to moderate hypertension.
- Trial name
- NCT00413413
- Testing
- Valsartan/amlodipine 80/5 mg, Valsartan 80 mg, Valsartan 160 mg
- Where
- 19 sites in China
- Volunteers
- 1,134 people
- Sponsor
- Novartis Pharmaceuticals
Drug Poisoning
StO2 Performance Measured on Admission to the Emergency Department in the Assessment of Drug Poisoning
The primary purpose of the protocol is to evaluate the StO2 performance measured at the admission to the emergency department to identify hemodynamic failure at the admission or within the first three hours of monitoring patients…
- Trial name
- IMACS (NCT01861262)
- Testing
- Measurement of StO2
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Dental Anxiety
Modification of Blood Pressure Levels and Oxygen Saturation in Patients Undergoing Conscious Sedation
The objective is to compare the changes produced in cardiological and respiratory parameters in three groups of patients undergoing oral surgery.
- Trial name
- NCT03789942
- Testing
- Oral surgery
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Clinica Luis Ortiz
Acute Ischemic Stroke
Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2)
Though intravenous thrombolysis has been shown to improve symptoms in acute ischemic stroke patients, the recanalization rate remains low (22.6%) and only around 30% of patients benefit from the treatment.
- Trial name
- NCT06677970
- Testing
- BP lowering drugs (nicardipine, labetalol, urapidil), BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil)
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Yonsei University
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