Clinical trials: Blood Sample
Immune Thrombocytopenia
The Association Between Platelet Reactivity and Bleeding Risk in Adult ITP
It seems reasonable to assume that patients who present significant bleeding symptoms may have different quality of platelets than those without bleeding.
- Trial name
- NCT03377439
- Testing
- Platelet function tests
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shandong University
Plasmodium Falciparum Malaria
AMA1-C1/Alhydrogel + CpG 7909 for Malaria
The purpose of this study is to test an experimental malaria vaccine in about 75 healthy adults, 18-45 years of age. The study will also test an experimental adjuvant which is a material added to a vaccine to help the body make…
- Trial name
- NCT00344539
- Testing
- AMA1-C1/Alhydrogel®, CPG 7909 Oligodeoxynucleotide (VaxImmune®)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pain, Newborn
Developing a Portable Therapeutic Baby Nest for Newborns and Evaluation During Venous Blood Collection
The neonatal period covers the first 28 days after birth. Newborns may experience problems such as jaundice, restlessness, nasal congestion, respiratory distress, and vomiting in this process, and for these reasons, children are…
- Conditions
- Pain, Newborn, Comfort
- Trial name
- NCT05442619
- Testing
- Venous blood collection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Hepatitis C, Deglutition Disorders
Bioequivalence Study of Crushed Elbasvir/Grazoprevir Compared to the Whole Tablet
Elbasvir/grazoprevir (Zepatier®) is a once-daily tablet for the treatment of chronic hepatitis C virus (HCV) GT1a, 1b or 4 infection containing the NS5A inhibitor elbasvir (ELB) 50 mg and the NS3/4A protease inhibitor grazoprevir…
- Trial name
- CRUSADE-2 (NCT03817619)
- Testing
- Zepatier whole tablet, Zepatier crushed tablet
- Where
- Netherlands
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infections
Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)
This is an open-label, single-sequence, multiple-dose, 3 cohort study to investigate the effects of DRV/RTV and/or ETR on the pharmacokinetics (PK) of GSK3640254 and the effects of GSK3640254 on the PK of DRV/RTV and/or ETR.
- Trial name
- NCT04630002
- Testing
- GSK3640254, Darunavir/Ritonavir (DRV/RTV), Etravirine (ETR)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Reproducibility of Results, Safety Issues
Non-Invasive Blood Test Cross-Validation Study
The study considers a cross-validation approach to determine the effectiveness of a non-invasive comprehensive metabolic panel (NICMP), relative to the venipuncture method.
- Trial name
- NCT03991637
- Testing
- Non-Invasive Comprehensive Metabolic Panel
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Joseph Allen Jr.
Cystic Fibrosis, Pancreatic Insufficiency
Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea
*The purpose of this study is to develop a more accurate, reliable, specific and more acceptable alternative clinical test to the 72-hour stool and diet collection for quantifying fat malabsorption in people with CF and…
- Trial name
- MBT (NCT00572975)
- Testing
- Pentadecanoic acid (PA) and Triheptadecanoin (THA)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Blood Pressure
Comparing Accuracy Between Cuffless Wrist Worn and Cuffed Ambulatory BP Monitoring Devices
Wrist worn devices can help record Blood Pressure (BP) throughout the day. As such devices are becoming increasingly affordable, they could help improve awareness, early diagnosis, and treatment of high and uncontrolled BP.
- Trial name
- Continuum BP (NCT06573801)
- Testing
- Aktiia Bracelet, Healthstats BPro Evo, Spacelabs OnTrak Ambulatory Blood Pressure monitor
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Chronic Hepatitis B
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
This study is an open-label, ascending dose phase 1a trial to assess the safety and immunogenicity of a heterologous protein prime/MVA boost therapeutic hepatitis B vaccine
- Trial name
- NCT05727267
- Testing
- HEPLISAV B; TherVacB, TherVacB
- Where
- 2 sites in Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Blood Pressure, Hypertension
Bioavailability of Hesperidine and Narirutin From Orange Juice to Identify Metabotypes in Hypertension
Flavonoids are polyphenolic compound mainly found in fruits and vegetables with numerous beneficial health effects as protection against cardiovascular diseases by an antihypertensive effect.
- Trial name
- FLAVOTIP (NCT04234100)
- Testing
- Orange juice rich in hesperidin and narirutin
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Infant, Newborn, Disease, Pain, Acute
Pain in Newborn Heel Blood Collection
This study was conducted to evaluate the effect of white noise and therapeutic touch on pain in newborn heel blood collection.Questions including the sex of the newborns, postnatal age, gestational age, birth weight, height, head…
- Trial name
- NCT05510271
- Testing
- White Noise, Yakson Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Adolescents, Physical Activity
School-based HIIT and Dose-Response Effects
There are experimental evidences of the importance of high intensity exercises in health outcomes improvement. However, there are limited knowledge about possibility to affect health outcomes in adolescents through exercises…
- Conditions
- Adolescents, Physical Activity, Adipose Tissue, Blood Pressure
- Trial name
- PEER-HEART (NCT06431230)
- Testing
- standard high-intensity interval training, plyometric high-intensity interval training
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Healthy, Renal Impairment
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
This study is open to adults aged between 18 and 80 years of age with a body mass index (BMI) of 20 to 40 kg/m2. People with or without kidney problems can take part in the study.
- Trial name
- NCT06352411
- Testing
- BI 456906
- Where
- 2 sites in Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Body Composition, Zinc Status
Dietary Patterns, Inflammation, Zinc Status, and Body Composition in Multi-Ethnic Women of Reproductive Age in Jakarta
This study aims to determine the relationship between dietary patterns and hair zinc levels with body composition, tumor necrosis factor alpha (TNF-α), and blood pressure in women of reproductive age from different ethnic…
- Conditions
- Body Composition, Zinc Status, Dietary Analysis, TNF Alpha
- Trial name
- DIVERSE (NCT07170904)
- Testing
- Not applicable- observational study
- Where
- Indonesia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hyperlipidemia
Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes
The purpose of this study is to evaluate the effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.
- Trial name
- PSE-MO (NCT00928616)
- Testing
- margarine + plant sterol esters
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Saarland
Hypertension
Bioequivalence Study of Azilsartan Medoxomil 80 mg Tablets (Gedeon Richter Plc., Hungary) and Edarbi® 80 mg Tablets (JSC Nizhpharm, Russia)
ACEis are among the most widely used classes of antihypertensive drugs. ARBs have a similar antihypertensive efficacy and protective effect as ACEis, albeit with a somewhat different mechanism for RAS inhibition and a smaller…
- Trial name
- NCT06990204
- Testing
- Azilsartan medoxomil 80 mg tablet, Edarbi® 80 mg tablets
- Where
- Russia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gedeon Richter Plc.
Hyperglycaemia
Effects of Polyphenols Found in Pomegranate Juice on Postprandial Blood Glucose in Vivo
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT02624609
- Testing
- Control without pomegranate juice, Test with pomegranate juice
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Healthy
A Study in Healthy Men to Investigate Uptake and Distribution of Lu AF88434 in the Brain
This study will investigate how much of Lu AF88434 will get into the blood and the brain in healthy men
- Trial name
- NCT04538014
- Testing
- Lu AF88434, [11C]-Lu AF88434
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Overweight, Healthy
Effects of Normobaric Hypoxia and Different Exercise Modes on Blood Glucose Regulation in Overweight Adults
Obesity is a major global health issue and a primary risk factor for metabolic-related disorders. While physical inactivity is one of the main contributors to obesity, it is a modifiable risk factor with exercise training as an…
- Conditions
- Overweight, Healthy, Physical Inactivity
- Trial name
- NCT05627804
- Testing
- Low-moderate intensity exercise, Sprint interval training, Functional exercise
- Where
- Malaysia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Swinburne University of Technology
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