Clinical trials: Blood Sugar (Glucose) Control
Type 2 Diabetes
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
A Randomized Control Trial (RCT) with 1:1 randomization of adults newly diagnosed with type 2 diabetes (T2D) to Routine Care (RC) and RC + Glycemic Excursion Minimization (RC+GEM); a program that provides RC in addition to…
- Trial name
- GEM (NCT05766735)
- Testing
- Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Chiara Fabris, PhD
Hyperglycemia, Critical Illness
Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)
The primary aim of the study is to compare the effects of the two blood glucose targets on 90 day all-cause mortality in Intensive Care patients who are predicted on admission to stay in the ICU for at least one full calendar…
- Trial name
- NCT00220987
- Testing
- Intensive Insulin Therapy, Conventional Insulin therapy
- Where
- Australia
- Volunteers
- 6,104 people
- Sponsor
- The George Institute
Hydration, Blood Glucose
Clinical Trial to Evaluate the Efficacy of a Sport Drink After High-intensity Aerobic Exercise
Although the general effectiveness of carbohydrate/electrolyte-based functional sports drinks on rehydration, recovery and sports performance has been widely demonstrated, there is controversy about the amounts, proportions and…
- Conditions
- Hydration, Blood Glucose, Sport Recovery, Microbiota
- Trial name
- NCT05352724
- Testing
- Hydration drink
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bioithas SL
Diabetes
A Placebo-Controlled, Randomized, Safety and Efficacy Study to Evaluate the Change in Hemoglobin A1c Levels in Type 2 Diabetic Subjects While Taking Nutralin
The purpose of this clinical research study is to evaluate the effects an investigational food product has on the blood sugar and insulin levels in individuals with diabetes.
- Trial name
- NCT01275027
- Testing
- Nutralin
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Continuous Glucose Monitoring, Diabetes, Gestational
Early Pregnancy Lifestyle and Glucose Patterns: A Substudy of TOFFFY
The goal of this clinical trial is to examine how daily behavioral patterns in early pregnancy, including sleep, physical activity, and meal timing, influence continuous glucose dynamics and subsequent risk of gestational…
- Conditions
- Continuous Glucose Monitoring, Diabetes, Gestational, Diet During Pregnancy, Meal Time
- Trial name
- NCT07534670
- Testing
- Continuous glucose monitor (CGM), Wrist actigraphy device, AI-based dietary and meal timing logging mobile application
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Type 2 Diabetes Mellitus
Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients
The goal of this study is to demonstrate that leucine in combination with a low does of metformin can serve as an adjunct to diet and exercise to improve blood glucose levels in type 2 diabetic subjects.
- Trial name
- NCT02151461
- Testing
- Low Metformin, Metformin, Mid Metformin
- Where
- 9 sites in United States
- Volunteers
- 96 people
- Sponsor
- NuSirt Biopharma
Critical Illness
Individualized Blood Glucose Control in ICU. The CONTROLING Study. A Double Blinded Multicentric Randomized Study.
During the last 2 decades, the management of hyperglycemia in critically ill patients has become one of the most discussed topics in the intensive-care field.
- Trial name
- CONTROLING (NCT02244073)
- Testing
- Human insulin - Insulin administration to control blood glucose level.
- Where
- 12 sites in France
- Volunteers
- 2,069 people
- Sponsor
- Hospices Civils de Lyon
Insulin Pump Therapy
Closed Loop Pumps vs. Traditional Open Loop Pumps in Managing Blood Glucose Levels in T1DM Patients Fasting in Ramadan.
Our proposed study aims to build upon the existing findings by conducting a first-of-its-kind randomized controlled trial (RCT) that directly compares Advanced Hybrid Closed Loop (AHCL) and open-loop insulin delivery (OLID)…
- Trial name
- HybridRam (NCT06416202)
- Testing
- Advanced hybrid closed loop insulin pump, Open Loop Insulin Delivery system
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- King Fahad Medical City
Type 1 Diabetes
The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas
This study will test the hypothesis that a wearable automated bionic pancreas system that automatically delivers both insulin and glucagon can improved glycemic control vs.
- Trial name
- NCT01833988
- Testing
- Bi-hormonal Bionic Pancreas, Usual Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Nutrition, Healthy
Acute and Long-term Health Effects of Various Carbohydrates on Blood Glucose Management in Humans
Dietary fibre, especially soluble fibre, has several health benefits such as lowering the risks for cardiovascular disease, stroke, diabetes, obesity, and gastrointestinal diseases.
- Trial name
- NCT06554002
- Testing
- Control, Treatment
- Where
- Singapore
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Postprandial Hyperglycemia
Investigation of Milk Peptides on Postprandial Blood Glucose Profile
Aim of the study is to investigate the effect of two different dosages of milk peptides on postprandial blood glucose profile in prediabetic subjects compared to placebo.
- Trial name
- NCT03932695
- Testing
- Low dose milk peptide, High Dose milk peptide
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
Critical Illness, Hyperglycemia
Multicentre LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness (LOGIC-2)
Most critically ill patients are confronted with hyperglycaemia, which is associated with an increased mortality and morbidity risk.
- Conditions
- Critical Illness, Hyperglycemia, Hypoglycemia
- Trial name
- LOGIC-2 (NCT02056353)
- Testing
- LOGIC-Insulin algorithm, Paper protocol
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 1,550 people
- Sponsor
- KU Leuven
Cardiovascular Disease, Diet Modification
Chinese Heart Healthy Diet for People With High Cardiovascular Risk in China (DECIDE-Diet)
The DECIDE - Diet (Diet, ExerCIse and carDiovascular hEalth - Chinese Heart Healthy Diet for People With High Cardiovascular Risk in China) is to evaluate the effects of CHH-diet in reducing blood pressure in Chinese people with…
- Conditions
- Cardiovascular Disease, Diet Modification, Randomized Controlled Trial
- Trial name
- NCT03882645
- Testing
- CHH-diet, local usual diet
- Where
- 6 sites in China
- Volunteers
- 265 people
- Sponsor
- Peking University
Post-prandial Glycaemia
Effect of Acai Berry Consumption on Blood Glucose Levels in Healthy Adults
Type 2 Diabetes Mellitus is a chronic disease that results in hyperglycaemia. This study aimed to identify whether the anthocyanins contained in acai berries can mitigate postprandial glycaemia in healthy adults when consumed in…
- Trial name
- NCT04748575
- Testing
- Acai smoothie
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Gestational Diabetes Mellitus
Flash Glucose Monitoring in Gestational Diabetes Mellitus: Study Protocol for a Randomized Controlled Trial
Gestational diabetes mellitus (GDM) is glucose intolerance diagnosed for the first time in pregnancy. According to literature GDM affects 3-10% of pregnant women and is a risk factor for multiple maternal and fetal complications.
- Trial name
- FLAMINGO (NCT04422821)
- Testing
- Flash Glucose Monitoring, Self-Monitoring of Blood Glucose
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus, Type 1
Efficacy Study on the Control of Blood Glucose Concentration in Type 1 Diabetic Patients
·Main objective: To compare the variability of fasting capillary blood glucose concentration, observed with insulin glargine combined with insulin glulisine and with insulin detemir combined with insulin glulisine, in type 1…
- Trial name
- VARIABILITE (NCT00271284)
- Testing
- insulin glulisine / insulin glargine, insulin glulisin / insulin detemir
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Sanofi
Diabetes Mellitus Type 2
Mulberry Leaf Extract and Blood Glucose Control in Diabetics
Mulberry leaf teas or extracts are used as a natural remedy for diabetes in some countries. Animal studies have shown some effect of mulberry leaf extract on blood glucose.
- Trial name
- NCT01305434
- Testing
- Mulberry leaf extract effect on post prandial blood glucose
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Craig, Nancy, M.D.
Type 2 Diabetes Mellitus
A Study to Assess the Efficacy and Safety of ASP1941 in Japanese Type 2 Diabetes Patients
This study is to compare the efficacy and safety of ASP1941 with placebo in Japanese patients with type 2 diabetes mellitus.
- Trial name
- NCT01057628
- Testing
- ipragliflozin
- Where
- 5 sites in Japan
- Volunteers
- 130 people
- Sponsor
- Astellas Pharma Inc
Type2 Diabetes
The Blood Glucose Control in Patients With Type 2 Diabetes Treated With Glargine
Glargine is commonly used in insulin supplemental therapy in patients with type 2 diabetes(T2D) at present. This study aims to investigate the current status of blood glucose control in patients with T2D treated with glargine.
- Trial name
- NCT03566472
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hyperglycemia, Hematopoietic Stem Cell Transplantation
Glucose Control In Hematopoetic Stem Cell Transplant
To determine whether intensive glucose control results in improved mortality and reduced hospital stay length by performing a randomized trial of intensive glucose management (blood glucose goal 110 mg/dl) using continuous IV…
- Trial name
- NCT00582036
- Testing
- Regular Insulin, Deployment of the MiniMed Paradigm monitoring device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma