Clinical trials: Blood Tests
HIV Infections
A Study to Test the Effect of Cyclosporine on the Immune System of Patients With Early HIV Disease
The purpose of this study is to determine the safety and effectiveness of low doses of cyclosporine (CsA) in patients with early HIV infection and to evaluate its effect on the immune system.
- Trial name
- NCT00000880
- Testing
- Cyclosporine
- Where
- 12 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Seropositivity
Community-based Distribution of Oral HIV Self-testing Kits
This cluster randomised trial aims to evaluate the impact of a pilot HIVST intervention of oral HIV self-testing (HIVST) as an option for HIV testing, in addition to the offer of home-based rapid HIV testing, through community…
- Trial name
- NCT02994329
- Testing
- OraQuick® HIV Self-Test (Orasure Technologies, Thailand)
- Where
- Zambia
- Volunteers
- 8,080 people, healthy volunteers welcome
- Sponsor
- Zambart
Locally Advanced Cervical Cancer
Assessment of Prognosis Using Peripheral Blood Circulating Tumor DNA in Patients With Cervical Cancer
This observational study is conducted to assess the value of using peripheral blood ctDNA to detect dynamic changes in HPV and genetic variants in predicting the prognosis of patients with locally advanced cervical cancer, as…
- Trial name
- NCT05602831
- Testing
- detect HPV and genetic variants
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Fudan University
Pediatric Cancer, Cancer Survivor
LOG-I - Impact Study of LOG-AFTER Software on Long-term Monitoring of Former Patients (LOG-I - LOG-Impact Study)
Childhood cancer survivors represent a high-risk population that requires risk-based follow-up. Follow-up recommendations have been harmonized.
- Conditions
- Pediatric Cancer, Cancer Survivor, Hemato-oncologic Patients
- Trial name
- LOG-I (NCT06939322)
- Testing
- Use of the Log-AFTER software
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Angers
Microdeletion Syndromes, Trisomy 21
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
The purpose of this study is to collect blood from families with a child who has been diagnosed with a chromosomal disorder including microdeletions in order to further develop a non-invasive prenatal screening test based on…
- Conditions
- Microdeletion Syndromes, Trisomy 21, Trisomy 18, Trisomy 13
- Trial name
- Microdel Triad (NCT02109770)
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- Natera, Inc.
Hepatitis C, Hepatitis C, Chronic
Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs
This project aims to evaluate two strategies of Hepatitis C virus (HCV) testing compared to standard of care among people who inject drugs at needle and syringe program (NSP) services in Australia, to see if it can improve the…
- Trial name
- TEMPO (NCT04014179)
- Testing
- Xpert HCV Viral Load Fingerstick, Aptima HCV Quant DX Assay
- Where
- 17 sites in Australia
- Volunteers
- 1,801 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Mild Dementia, Mild Cognitive Impairment
The Swedish BioFINDER - Primary Care Study
The overall aim of the study is to improve the diagnostic accuracy of AD and cognitive impairment in primary care settings to ensure better care and treatment as well as facilitate correct referrals to specialized memory clinics.
- Conditions
- Mild Dementia, Mild Cognitive Impairment, SCD, Alzheimer Disease
- Trial name
- ADetect (NCT06120361)
- Testing
- Plasma APS 2 score, Plasma p-tau217/np-tau217, Plasma p-tau217
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Skane University Hospital
HIV Infections
Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV
This study will evaluate whether the HIV vaccine ALVAC vCP1452 given in combination with interleukin-2 (IL-2), also known as aldesleukin, can increase immune system function in people with HIV infection.
- Trial name
- NCT00056797
- Testing
- ALVAC HIV vaccine (vCP1452), Interleukin-2
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Performance and Usability Evaluation of the Atomo HIV Self-Test
The study seeks to enroll 501+ patients to use a HIV self testing device to test for HIV in a blood sample drawn by finger prick.
- Trial name
- NCT03755986
- Testing
- ATOMO Diagnostic Test
- Where
- Australia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Holdsworth House Medical Practice
HIV Positive
Thinking and Memory Problems in People With HIV
Background: People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration.
- Trial name
- NCT01875588
- Where
- United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Thrombocythemia, Essential
Hematology, IMG-7289, LSD1 (Lysine-Specific Demethylase 1) Inhibitor, Essential Thrombocythemia (ET), Ph 2
This is a single-center, open-label investigator-initiated trial evaluating the effects of IMG-7289 administered orally once daily in patients with essential thrombocythemia.
- Trial name
- NCT04081220
- Testing
- IMG-7289
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cardiac Valve Disease
Ultrafiltration on Coagulation Performance in Cardiac Surgery
In cardiac surgery patients with CPB-induced dilutional coagulopathy, ultrafiltration (UF) was applied to reduce free water and concentrate all blood components before the weaning from CPB.
- Trial name
- NCT05252559
- Testing
- ultrafiltration, maximal clot firmness in EXTEM assay of ROTEM test
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Konkuk University Medical Center
HIV Infection
Integrated Care Centers to Improve HIV Outcomes in Vulnerable Indian Populations
This is a cluster randomized trial to evaluate the effectiveness of integrated care centers (ICC) to improve access to HIV testing, prevention services, and treatment among high-risk populations of injection drug users (IDU) and…
- Trial name
- NCT01686750
- Testing
- Integrated care centers
- Where
- India
- Volunteers
- 21,726 people
- Sponsor
- Johns Hopkins University
Asthma, Allergies
Cohort Study of the Patterns of Microvesicles in the Serum of Participants With Atopic and Non-atopic Asthma
The purpose of this study is to determine if a simple blood test can help in disease management, particularly asthma. This will be researched by looking at certain features of the blood and to compare asthmatics without allergies…
- Trial name
- NCT00700726
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Ohio State University
Cancer
Blood Samples Were Taken From Patients Undergoing Oncological Treatment in Order to Validate the TST79 Molecular Test
The pathological anatomy laboratory, which is managed by the IPG, would involve monitoring patients being treated for cancer and receiving care at the GHDC in order to take blood samples from those in whom the presence of plasma…
- Trial name
- OncoSang-TST79 (NCT07868640)
- Testing
- Gene-alteration pair (G-A)
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Grand Hôpital de Charleroi
Acute Leukemia
Change of Fatigue and Physical Fitness in Hospitalized Hematology Patients
The purposes of this study are to (1) explore the severity of symptom of leukemia patients experienced before and after chemotherapy in hospital, (2) investigate the trajectories of the fatigue and physical fitness, and their…
- Trial name
- NCT01603290
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- National Taiwan University Hospital
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Ketogenic Dieting, Ketosis
Characterization of a Portable Solid-State Breath Acetone Testing Device for Real-Time Ketosis Status
The primary purpose of this study is to characterize the performance and utility of a novel breath acetone meter developed by Readout, Inc.
- Trial name
- NCT04130724
- Testing
- Blood ketone testing, Breath ketone testing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Readout, Inc.
Delta Hepatitis
Determination of New Detection and Quantification Thresholds for Serological and Molecular Tests for Hepatitis Delta Virus (HDV) Using Capillary Blood on Blotting Paper (DBS)
The Delta hepatitis virus (HDV) is a satellite virus that requires the presence of hepatitis B virus (HBV) for infection. Approximately 5% of HBV-infected individuals, or about 12 million people globally, are also carriers of…
- Trial name
- SACADE (NCT06649396)
- Testing
- Dried Blood Spot, Analysis on plasma
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Validation of New Test NIPT
Validate Non-invasive Prenatal Tests for the Detection of Chromosomal Abnormalities
This study will be conducted on pregnant patients for whom there is a suspicion of a chromosomal abnormality of the fetus. These are patients eligible for non-invasive prenatal screening as part of their usual pregnancy…
- Trial name
- NIPT (NCT05618431)
- Testing
- NIPT
- Where
- France
- Volunteers
- 1,790 people
- Sponsor
- CerbaXpert