Clinical trials: Blood Volume
Healthy
Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers
The study was a randomized, single blind, uni-center pivotal study in male and female healthy volunteers, to determine capillary blood volume and pain perception obtained in a process of puncturing with different safety lancets.
- Trial name
- NCT04001348
- Testing
- Acti-Lance Lite, Acti-Lance Universal, Acti-Lance Special
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Anemia
Phenotyping Acute Non-Severe Anemia in the Emergency Department
Anemia is traditionally diagnosed and managed using circulating hemoglobin concentration ([Hb]). However, [Hb] is influenced by plasma volume and may not accurately reflect the total amount of hemoglobin available for oxygen…
- Trial name
- PHENOEMEMIA (NCT07761104)
- Testing
- Total hemoglobin mass measurement, Focused transthoracic echocardiography, Near-infrared spectroscopy
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Intradialytic Hypertension
Mechanisms of Increased Ambulatory Blood Pressure in Patients With Intradialytic Hypertension
The purpose of this study is 1) to determine what physiologic factors (extracellular fluid overload or vasoconstriction) contribute more to increased blood pressure levels between dialysis treatments in hemodialysis patients…
- Trial name
- NCT01862497
- Testing
- Carvedilol vs. Prazosin
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Texas Southwestern Medical Center
Anemia
Iron Prophylaxis for Anemia in Infants With Cyanotic Congenital Heart Disease
Anemia is a common disorder in infants with one working chamber of the heart that pumps blood. Anemia is when the level of healthy blood cells becomes too low.
- Trial name
- NCT00459225
- Testing
- Iron (ferrous sulfate)
- Where
- United States
- Sponsor
- Emory University
Heart Diseases
Regional Cerebral Oxygenation and Brain Blood Volume During Cardiac Surgery Using the NeurOS System
Study of Regional Cerebral Oxygenation and Brain Blood Volume changes during Cardiac Surgery using the NeurOS system
- Trial name
- COBBV-CS (NCT03969836)
- Testing
- NeurOS system
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University of Louisville
Surgical Procedure, Unspecified
Non-invasive Assessment of Arterial Blood Pressure and Functional Hemodynamic Parameters
Cardiac output can be monitored using different invasive devices. Nexfin HD is a new, noninvasive device that uses model flow technology to measure stroke volume and thus computes cardiac output (CO).
- Trial name
- NCT01292759
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Johannes Gutenberg University Mainz
Diabetes
The Characterization of Blood Volumes of Commercially Available Lancing Devices
Characterize expressed blood volume ≥1μL across representative, commercially available lancing device systems using finger sticks.
- Trial name
- NCT01914302
- Testing
- Delica Lancing Device, Flash Lancing Device, Easy Touch Lancing Device
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Facet Technologies
Reference Values
Reference Values for Pulse Induced Continuous Cardiac Output (PiCCO) Variables in Children
Pulse induced continuous cardiac output (PiCCO) is an established technology for measurement of advanced hemodynamic variables in critically ill patients.
- Trial name
- NCT01283529
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Blood Loss
Effect of Low Tidal Volume on Blood Loss During Laparoscopic Hepatectomy
To explore the effect of low tidal volume on blood loss and gas exchange during laparoscopic hepatectomy
- Trial name
- NCT03399123
- Testing
- Tidal volume
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Southwest Hospital, China
Acute Decompensated Heart Failure, Fluid Overload
A Feasibility Study on Ultrafiltration and Blood Volume Measurements
The objective of this feasibility study is to characterize the performance of the Aquadex FlexFlow® System with the hematocrit (HCT) feature in conjunction with Daxor's blood volume analyzer (BVA-100).
- Trial name
- NCT04241718
- Testing
- Aquadex FlexFlow System and BVA-100
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Nuwellis, Inc.
Drug Dependence
Brain Function in Response to Motivational Stimuli
This study seeks more information about the biology of substance dependency by exploring the brain areas involved in feeling positive and negative emotions.
- Trial name
- NCT00047866
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Heavy Menstrual Bleeding, Uterine Fibroid
LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The purpose of this study is to determine the benefit of relugolix 40 milligrams (mg) once a day co-administered with estradiol (E2) 1 mg and norethindrone acetate (NETA) 0.5 mg compared with placebo for 24 weeks on heavy…
- Trial name
- NCT03103087
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 127 sites in United States, Belgium and 6 more
- Volunteers
- 382 people
- Sponsor
- Myovant Sciences GmbH
Hemodynamics Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.
- Conditions
- Hemodynamics Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- PH (NCT03861364)
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Helse Fonna
Blood Loss
Evaluation of the Zynex Blood Volume Monitor in Healthy Adult Patients During a Blood Draw
Non-invasive monitoring to measure changes in blood volume.
- Trial name
- NCT01846195
- Testing
- CM 1500
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zynex Monitoring Solutions
Transfusion
Use of Cell Salvage Post-operatively in Infants to Decrease Use of Allogeneic Blood Product Transfusions
Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators.
- Trial name
- cell salvage (NCT01211366)
- Testing
- Cell Saver RBCs, Conventional volume infusion
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Rochester
Complication of Hemodialysis
Microcirculation During Haemodialysis
SDF is validated by measuring changes in microcirculation in sepsis patients with MOF (Boerma studies). SDF is validated by measuring changes in microcirculation in stable chronic hemodialysis patients (NDT 2009 Bemelmans).
- Trial name
- NCT01396980
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Frisius Medisch Centrum
Renal Calculi, Kidney Stones
Transient Apnea During Flexible Ureteroscopic Lithotripsy
Respiration-related renal motion may reduce targeting stability during flexible ureteroscopic laser lithotripsy and thereby decrease lithotripsy efficiency.
- Trial name
- TA-fURS (NCT01835600)
- Testing
- Regular mechanical ventilation during flexible ureteroscopic lithotripsy, Small tidal-volume ventilation during flexible ureteroscopic lithotripsy, Transient apnea during flexible ureteroscopic lithotripsy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese Medical Association
Neonatal Intensive Care
Estimation of Cardiac Output in Neonatal ICU Using an Ultrasound Dilution Technique
Presently there is no apparatus, clinically available, for routine determination of cardiac output (CO) in children. The goal of this research is to develop new technology that will help determine CO in neonates.
- Trial name
- CH (NCT01610622)
- Testing
- COstatus cardiac output measurement with isotonic saline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Transonic Systems Inc.
Heart Failure Congestive
VAPorized Administration of Bumetanide for Outpatient Relief in Heart Failure
This trial is seeking to determine whether a single 4mg intranasal dose of bumetanide acutely reduces pulmonary artery pressure and blood volume in the outpatient setting for patients with heart failure and an implanted device…
- Trial name
- VAPOR-HF (NCT07375212)
- Testing
- Bumetanide, intranasal 4mg
- Where
- United States
- Sponsor
- Prisma Health-Upstate
Caffeine
Caffeine Supplementation, Resistance Training and Blood Antioxidant Status
The purpose of this study is to verify the effect of acute caffeine intake on resistance training volume and blood antioxidant status, in a randomised, double-blind, placebo-controlled crossover trial.
- Trial name
- NCT05230303
- Testing
- Caffeine supplementation
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice