Clinical trials: Blunt Trauma
Traumatic Blunt Chest and/or Blunt Abdominal Injury
Hemodynamic and Ventilatory Responses to Head-down Postural Drainage Position
The purpose of this study is to explore acute hemodynamic and ventilatory responses to head-down 30 degree postural drainage position in patients with blunt chest and/or abdominal injury in the traumatic intensive care unit.
- Trial name
- NCT01668875
- Testing
- Head down 30 degree postural drainage position, Horizontal supine lying
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Head Injury Trauma Blunt
Platelet Function Analysis in Head Trauma: ASA/Plavix
The investigators are assessing the platelet function analysis of those who sustained significant head trauma while on aspirin or plavix and to assess if any qualitative difference is obtained if platelets are administered.
- Trial name
- ASA/Plavix (NCT01534117)
- Testing
- Platelets, DDAVP
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Chang, Steve S., M.D.
Blunt Chest Wall Trauma
STUMBL vs TTSS in Predicting Morbidity and Mortality of Blunt Chest Trauma
This study aim to compare the effectiveness of the STUMBL Score and the Thoracic Trauma Severity Score (TTSS) in predicting morbidity and mortality in patients with blunt chest wall trauma, and to evaluate which scoring system…
- Trial name
- NCT07270354
- Testing
- Chest X-Ray, Computed Tomography (CT) Chest (with or without contrast)
- Volunteers
- 124 people
- Sponsor
- Assiut University
Rib Fractures, Thoracic Injuries
Ultrasound for Diagnosing Costochondral Joint Separation
This study aims to evaluate the diagnostic effectiveness of ultrasound in detecting costochondral joint separation in patients with blunt thoracic trauma.
- Trial name
- NCT06766721
- Testing
- Ultrasound (USG)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Caner İşevi, MD
Blunt Injury of Thorax, Multiple Rib Fractures, Involving Three Ribs
Low Dose Ketamine for Blunt Thoracic Trauma
The goal of this Randomized controlled double-blinded trial is to compare the addition of a ketamine infusion to placebo, when added to standard care in adult blunt trauma patients with multiple rib fractures.
- Trial name
- NCT06236113
- Testing
- Ketamine 1 Mg/mL-NaCl 0.9% Intravenous Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- North Memorial Health Care
Aortic Rupture
Analysis of Risk Factors for Death After Blunt Traumatic Rupture of the Thoracic Aorta
Aortic injuries after blunt thoracic trauma are compared to the great incidence of accidents relatively rare, but potentially serious leading to death at scene in most of the cases.
- Trial name
- NCT01632774
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- University of Zurich
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Blunt Chest Trauma
Non-Invasive Dynamic Monitoring-Guided Oscillation and Lung Expansion for Airway Clearance in Severe Blunt Chest Trauma: A Clinical Study
In our previous study, the investigators analyzed more than 30,000 cases from the National Trauma Center Database and found that 66.4% of patients with severe blunt chest trauma had concurrent rib fractures, 55.87% had multiple…
- Trial name
- NCT07432048
- Testing
- Different therapeutic interventions
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Blunt Injury of Thorax
Abg in Blunt Chest Trauma
This study aims to determine the value of ABG measurments in patients with blunt chest trauma and its role in prognosis of different outcomes and the results would aid the emergency physicians to speed up the management and…
- Trial name
- NCT05886946
- Testing
- ABG
- Volunteers
- 150 people
- Sponsor
- Assiut University
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Occult Bleeding, Hemorrhage
A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage
Early detection of ongoing hemorrhage (OH) before onset of hemorrhagic shock is a universally acknowledged great unmet need, and particularly important after traumatic injury.
- Conditions
- Occult Bleeding, Hemorrhage, Hemorrhagic Shock
- Trial name
- NCT04814810
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cellular Injury and Post-Cryogenic Recovery, Cryogenic Cellular Stress
Evaluation of In-Vitro Cryo Therapeutic Protocols on Human Cell Samples (TWH-CRYO-001)
This laboratory-based study evaluates the effects of controlled cryogenic preservation on human cell samples using Truway Health's in-vitro cryo therapeutic methodology.
- Conditions
- Cellular Injury and Post-Cryogenic Recovery, Cryogenic Cellular Stress, Cold-Induced Cellular Injury, Thermal Injury Response
- Trial name
- CRYO-IVT (NCT07321028)
- Testing
- Standard Laboratory Cryopreservation Procedure, Enhanced Laboratory Cryopreservation Procedure, Normothermic Cell Culture Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Truway Health, Inc.
Blunt Chest Trauma, Respiratory Failure
Combined Lung and Diaphragmatic Ultrasound to Predict Respiratory Failure in Blunt Chest Trauma
Blunt chest trauma is a leading cause of emergency hospital visits and can result in severe breathing complications such as hypoxemic respiratory failure.
- Conditions
- Blunt Chest Trauma, Respiratory Failure, Thoracic Injuries, Hypoxemic Respiratory Failure
- Trial name
- NCT07807566
- Volunteers
- 130 people
- Sponsor
- Assiut University
Blunt Injury of Thorax
STUMBL Score as a Risk Stratification Tool for Management of Blunt Chest Trauma Patients
The aim of this study is to assess validity of the STUMBL score in EGYPT for complications of blunt chest trauma without multi-trauma and immediate life-threatening injuries and identify patients at risk of in- hospital mortality…
- Trial name
- NCT06316375
- Volunteers
- 200 people
- Sponsor
- Assiut University
Chest Trauma
Sedation for Non-invasive Ventilation in Blunt Chest Trauma
Effectiveness of sedation using dexmedetomidine and ketamine to facilitate non-invasive ventilation sessions which improve overall outcome after blunt chest trauma
- Trial name
- NCT05175781
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Blunt Injuries
Nonoperative Management Protocol in Patients With Blunt Splenic Injuries
This study was designed to explore the adverse events and associated risk factors before and after protocol-based NOM of BSI over a 12-year period in our institution.
- Trial name
- NCT03943355
- Testing
- Patient before cohort (2005-2010), Patient after cohort (2011-2016)
- Volunteers
- 399 people
- Sponsor
- Chang Gung Memorial Hospital
Trauma Blunt, Orthopedic
The Healing and Empowerment Actions for Recovery From Trauma (HEART) Trial
The HEART Trial aimed to determine if wrap-around psychosocial support for patients who sustain moderate to severe trauma requiring orthopedic surgery intervention improves outcomes for patients (Aim 1), care-partners (Aim 2)…
- Trial name
- HEART (NCT07584252)
- Testing
- Comprehensive trauma recovery programming (C-TRP), Standard of Care (Investigator Selected)
- Where
- 7 sites in United States
- Volunteers
- 804 people
- Sponsor
- Stephanie Di Stasi
Blunt Trauma, Penetrating Wound
Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
Primary Aim: To determine the feasibility and safety of hypotensive resuscitation for the early treatment of patients with traumatic shock compared to standard fluid resuscitation.
- Conditions
- Blunt Trauma, Penetrating Wound, Hemorrhagic Shock
- Trial name
- HypoResus (NCT01411852)
- Testing
- 0.9% Sodium Chloride 250 mL bolus, 0.9% Sodium Chloride 2000 mL bolus
- Where
- 6 sites in United States, Canada
- Volunteers
- 192 people
- Sponsor
- University of Washington
Blunt Thoracic Injury, Lung Ultrasound Score
High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients
This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou…
- Trial name
- NCT03430258
- Testing
- high-flow nasal cannula, Conventional oxygen therapy
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Trauma Injury, Trauma Blunt
Extremity Trauma At a Level 1 Trauma Center
Blunt vascular trauma to the lower extremity has been associated with injuries to the anteroposterior tibial arteries or popliteal artery in the form of transection, occlusion, or intimal injury.
- Conditions
- Trauma Injury, Trauma Blunt, Vascular Trauma
- Trial name
- NCT06402669
- Testing
- Packed Red Blood Cell Administration
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Arrowhead Regional Medical Center