Clinical trials: Body
Type 2 Diabetes, Obesity
Extracellular Vesicles, Insulin Action, and Exercise
Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people.
- Trial name
- NCT06546085
- Testing
- Exercise
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity
Vegetarian High Protein Weight Loss Diets
This study aims to investigate the mechanistic processes involved in protein-induced satiety/satiation during weight loss in humans.
- Trial name
- ALPROsoya (NCT02080325)
- Testing
- High Protein-Weight loss-Soy diet, High Protein-Weight loss-Meat
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obesity, Overweight
Dietary Protein Requirements on Unbalanced Diets
The objective of this study is to determine ad libitum daily energy and protein intake, energy balance and appetite profile in response to protein/carbohydrate and fat ratio over 12 consecutive days, also as a function of age…
- Trial name
- NCT01320189
- Testing
- Differences in protein content of meals
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Overweight and Obesity
ACTivating Fat OXidation Through Capsinoids
Prior evidence suggests that capsinoids ingestion may increase resting energy expenditure (EE) and fat oxidation (FATox) in humans, although whether they can modulate those parameters during exercise conditions remains poorly…
- Trial name
- ACTIFOX (NCT05156697)
- Testing
- Capsinoids + Exercise
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Obesity, Weight Loss
Bitter Taste and Weight Loss in Women
Individual food preferences are not considered in designing weight-loss therapies. This project will determine if short-term weight-loss is improved by matching participants with diets that reflect their genetically-determined…
- Trial name
- NCT01856660
- Testing
- Low-Carbohydrate Diet, Low-fat Diet
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Healthy, Obesity
Youth Lifestyle Intervention With Food and Exercise
Children who are overweight or obese can develop many health complications including diabetes, high blood pressure, high cholesterol and they break their bones more often than children who are of healthy body weights.
- Trial name
- MYLIFE (NCT01290016)
- Testing
- 2 servings dairy + exercise, 4 servings dairy + exercise, Control
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- McGill University
Metabolic Syndrome
Effectiveness of Pulse-Based Foods Combined With Exercise for Improving Components of the Metabolic Syndrome
The investigators specific objective is to determine the effectiveness of a pulse-based diet combined with an exercise training program for reducing the risk of metabolic syndrome in older adults.
- Trial name
- NCT00800033
- Testing
- Aerobic exercise training, pulse based diet
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Obesity, Type 2 Diabetes Mellitus
Gut Microbiota in Obesity and Diabetes
An altered gut microbiota composition has recently been linked to obesity and diabetes. The principal aim of this study was to investigate and compare the gut microbiota composition of obese, diabetic and control individuals.
- Trial name
- NCT02180191
- Testing
- Comparison of the gut microbiota composition
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Iron Absorption, Iron Requirements
Determination of Iron Absorption and Losses in People Living at High Altitude to Investigate the Requirements in This Population Group Using a Newly Developed Technique
Iron is an essential micronutrient responsible for a whealth of biological processes of the human body. Iron plays a fundamental role especially in oxygen transport, by binding to hemoglobin in the blood circulation.
- Conditions
- Iron Absorption, Iron Requirements, Altitude
- Trial name
- ARIA (NCT07142590)
- Testing
- Stable Isotopes
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Healthy, Overweight
The Effect of Blood Volume Changes on the Glucose Tolerance
In this study the investigators would like to elaborate on the mechanisms that lead to a higher insulin sensitivity after exercise training and a lower insulin sensitivity after bedrest.
- Trial name
- BV-GT (NCT02612597)
- Testing
- Bedrest, Exercise Training
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carsten Lundby
MACS Syndrome
MACS and Healthy Volunteers Bone Study
Adrenal adenoma is detected in 5-7% of adults and demonstrates mild autonomous cortisol secretion (MACS, dexamethasone suppression test >1.8 mcg/dl) in 50% of individuals with adenoma.
- Trial name
- NCT04343560
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Abdominal Obesity, Postprandial Lipemia
Alternating Energy Intake and Blood Fat Content After a Meal
Increasing evidence suggests that meal timing affects metabolic health. For example, intermittent fasting (IF) may have positive effects on plasma glucose and lipid levels, insulin sensitivity, and blood pressure.
- Conditions
- Abdominal Obesity, Postprandial Lipemia, Lipid Metabolism, Glucose Metabolism
- Trial name
- NCT04894526
- Testing
- Alternating Energy Intake, Regular Energy Intake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Overheating
Thermoregulatory Reactions of Medical Workers Who Use Personal Protective Equipment From Biological Hazards
This research will provide data on thermal condition, functional status and working conditions of medical workers who use personal protective equipment from biological hazards.
- Trial name
- NCT05091515
- Testing
- Personal protective equipment from biological hazard
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health"
Anorexia Nervosa
Perception and Representation of Internal Body in Anorexia Nervosa
This study focuses on representations of the interior of the body and interoceptive awareness in women with anorexia nervosa in comparison with women without eating disorders.
- Trial name
- PERCEPCOR (NCT03988218)
- Testing
- perceptive tests
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Esquirol
Adiposity
Characterization of Transient Alterations of Cutaneous Sensory Nerve Function by Cryolipolysis
Cryolipolysis with Zeltiq CoolSculpting device is a novel method of non-invasive fat removal. The technique works by application of cold plates to the skin surface for a single cooling cycle lasting 60 minutes, after which a…
- Trial name
- NCT01673113
- Testing
- Zeltiq CoolSculpting device
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Diabetes Mellitus, Type 2
Supplements for Controlling Resistance to Insulin
The purpose of this study is to evaluate the effects of a combination of hydroxcycitrate (HCA) and niacin-bound chromium, in conjunction with nutrition education, over a twelve week period.
- Trial name
- SCORE (NCT00699413)
- Testing
- nutrition education plus active supplement, nutrition education plus inactive supplement
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Dietary Modification
Beef Protein Supplementation in Endurance Athletes
The aim of this project is to investigate the potential benefits of combining a new protein beef hydrolysates extract with a regular endurance training programme on (a) body composition (b) performance (c) muscle structure (d)…
- Trial name
- Beef (NCT02675348)
- Testing
- Dietary Supplement: Beef Protein, Dietary Supplement: whey Protein, Dietary Supplement: CHO
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Resistance Training
Autonomic Modulation Recovery After Acute Resistance Exercise
To analyze the autonomic behavior in recovery post-acute resistance exercise performed in different intensities and body segments.
- Trial name
- NCT04569617
- Testing
- Resistance Training - UL endurance protocol, Resistance Training - UL strength protocol, Resistance Training - LL endurance protocol
- Where
- 2 sites in Brazil
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Obesity
Effect of Hydroxychloroquine Sulphate in Healthy Lean Females
The effect of an acute administration of hydroxychloroquine sulphate will be investigated on hedonic food intake, appetite related sensations and gastrointestinal hormone release in healthy female subjects.
- Trial name
- PLAQHV (NCT04005768)
- Testing
- Hydroxychloroquine Sulphate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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