Clinical trials: Body
Lewy Body Dementia With Behavioral Disturbance, Lewy Body Parkinson Disease
Telehealth in Lewy Body Dementia
Lewy body dementia (LBD) is the 2nd most common neurodegenerative dementia in the US. Optimal care requires an interdisciplinary approach, however often faced barriers include rural residence, limited access to specialists…
- Conditions
- Lewy Body Dementia With Behavioral Disturbance, Lewy Body Parkinson Disease, Lewy Body Disease
- Trial name
- NCT05014971
- Testing
- Tele-neurohub
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
5 and 7-year Follow-up of the YOMEGA Trial Cohort
Over the last 40 years, the Roux-en-Y Gastric Bypass (RYGB) has been the gold standard in the surgical management of morbid obesity. and is a validated bariatric procedure in France.
- Trial name
- YOMEGA 5-7y (NCT05549271)
- Testing
- Laparoscopic Mini-gastric bypass, Laparoscopic Roux-en-Y Gastric ByPass (RYGBP)
- Where
- 9 sites in France
- Volunteers
- 248 people
- Sponsor
- Hospices Civils de Lyon
Non Small Cell Lung Cancer, Non-small Cell Lung Cancer
Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
The development of stereotactic body radiation therapy (SBRT) for the treatment of stage I non-small cell lung cancer (NSCLC) has inspired a close partnership between thoracic surgery and radiation oncology.
- Trial name
- SORT (NCT05183932)
- Where
- 8 sites in United States, Canada
- Volunteers
- 446 people
- Sponsor
- Washington University School of Medicine
Heart Diseases, Cardiovascular Diseases
Strong People Strength Training Study
The Strong People Strength Training study aims to assess whether a community-based progressive strength training program can improve risk factors for diabetes and heart disease in older rural adults.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Diabetes, Sedentary Lifestyle
- Trial name
- NCT04203563
- Testing
- Strong People Strength Training
- Where
- 6 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Cornell University
Time Restricted Feeding, Obesity, Abdominal
Efficacy and Feasibility of Time-restricted Eating on Cardiometabolic Health in Adults With Overweight/Obesity
In Spain, obesity epidemic is one of the leading contributors of chronic disease and disability. Obesity is associated with higher morbidity and all-cause mortality risk especially when fat is stored in the abdominal area (i.e.…
- Conditions
- Time Restricted Feeding, Obesity, Abdominal, Cardiometabolic Syndrome
- Trial name
- EXTREME (NCT05310721)
- Testing
- Early time-restricted eating, Late time-restricted eating, Self-selected time-restricted eating
- Where
- 2 sites in Spain
- Volunteers
- 197 people
- Sponsor
- Universidad de Granada
Weight Gain, Obesity
Chromium Piccolinate in the Prevention of Weight Gain Induced by Serotonergic Medications Initiated on Psychiatric Inpatient Units.
A majority of patients who suffer from mental illness are treated with serotonin regulating FDA approved medications. Some of these medications also block histamine transmission, increase blood prolactin levels, induce insulin…
- Trial name
- NCT00759993
- Testing
- chromium piccolinate
- Volunteers
- 60 people
- Sponsor
- State University of New York - Upstate Medical University
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity, Schizophrenia
Bariatric Surgery in Patients With Schizophrenia
It is known that schizophrenia is associated with obesity in a significant number of patients and it implies a poor prognostic factor, with weight loss being important in this population.
- Trial name
- SCHIZOBAR (NCT06043206)
- Testing
- Bariatric Surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Neck Pain
Body Composition and Cervical Outcomes in Non-Specific Neck Pain
Non-specific neck pain (NSNP) is a common musculoskeletal condition that significantly affects quality of life, daily activities, and work productivity.
- Trial name
- NCT07388706
- Testing
- Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Diabetes, Obesity
Healthy Eating and Active Living Taught at Home
The purpose of this research study is to evaluate two different Parents as Teachers curriculums taught by parent educators, during home visits.
- Trial name
- HEALTH (NCT01567033)
- Testing
- PAT Curriculum + Health Information
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid…
- Trial name
- NCT07247084
- Testing
- Tirzepatide, Standard of Care
- Where
- 30 sites in United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Eli Lilly and Company
Locally Advanced Non-Small Cell Lung Cancer, Stage IIIb Non-small Cell Lung Cancer
Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC
This is a Phase II clinical trial evaluating the efficacy and safety of a new treatment approach for patients with locally advanced non-small cell lung cancer (NSCLC) that has spread to lymph nodes on the opposite side of the…
- Conditions
- Locally Advanced Non-Small Cell Lung Cancer, Stage IIIb Non-small Cell Lung Cancer, Stage IIIC Non-Small Cell Lung Cancer
- Trial name
- SACTION 2501 (NCT07309952)
- Testing
- Sintilimab, Paclitaxel, Carboplatin (AUC 5)
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Yang Hong
Post-surgical Scars, Hypertrophic Scars
Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)
The Surgical Care and Recovery with Laser Evaluation Trial (S.C.A.R.L.E.T.) is a prospective, single-center clinical study conducted at AdventHealth Medical Group Plastic and Reconstructive Surgery at Innovation Tower.
- Conditions
- Post-surgical Scars, Hypertrophic Scars, Scar Appearance Dissatisfaction, Aesthetic Surgical Outcomes
- Trial name
- SCARLET (NCT07359352)
- Testing
- ProFractional Laser Therapy and/or Broadband Light (BBL) Treatment
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Diabetes Mellitus, Type 2
C-Reactive Protein (CRP) in Obese Diabetic Women
The purpose of this study is to determine whether treatment with rosuvastatin for 6 months in obese type 2 diabetic women will improve their lipid profiles and thus prevent the progression to cardiovascular disease.
- Trial name
- NCT00262548
- Testing
- Rosuvastatin; improvement of lipid profile
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Hypertension, Overweight
The Effects of Aronia Juice Polyphenols on Cardiovascular Disease Risk
The existing scientific evidence from both in vitro and clinical trials supports the notion that polyphenols can modulate platelet function.
- Trial name
- AMARCord (NCT02800967)
- Testing
- Pure Aronia juice, Aronia juice-based beverage
- Where
- Serbia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Obesity, Diabetes
The Effects of Carbohydrate Source on Food Intake, Blood Glucose and Gut Hormone Response in Healthy Children
This study will compare the effects of commonly consumed carbohydrate sources such as potatoes, pasta and rice along with a fixed portion of meat on blood glucose, satiety and insulin levels among healthy body weight children.
- Trial name
- NCT02499107
- Testing
- Rice treatment, Pasta treatment, Boiled and mashed potato treatment
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Incretin Action, Obesity
Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
Tiny molecules (hormones) are released from the bowels and other organs to the bloodstream in response to meals in order to orchestrate the metabolism.
- Trial name
- NCT01232244
- Testing
- GLP-1 infusion, Glucagon infusion, Oxyntomodulin infusion
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Overweight
Regulation of Different IT on Vascular Function of Overweight Female University Students
This study investigates the effects of different interval training methods, specifically high-intensity interval training (HIIT) and sprint interval training (SIT), on vascular function in overweight female university students.
- Trial name
- NCT06658509
- Testing
- HIIT, SIT
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Obesity, Social Dominance
Subjective Social Status and Energy Balance
Investigators examined the associations between SSS, energy balance, food intake and changes in body composition following a high calorie lunch for 2 weeks.
- Conditions
- Obesity, Social Dominance, Social Behavior, Eating Behavior
- Trial name
- NCT03510364
- Testing
- Dietary intervention
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Cardiovascular Risk Factors
Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Obesity prevalence in elderly populations has increased in the last years, and the reduction of overweight and obesity is a priority target in populations of all age ranges worldwide.
- Trial name
- NCT01596309
- Testing
- Cocoa extract
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra