Clinical trials: Body Fat
Diabetes, Coronary Artery Disease
Epicardial Fat and Clinical Outcomes After Coronary Artery Bypass Grafting in Diabetics vs. Non Diabetics
Cardiovascular disease (CVD) is a group of diseases including both the heart and blood vessels, thereby including coronary heart disease (CHD). To date, diabetics have a higher incidence and prevalence of multivessels CHD.
- Trial name
- NCT03360981
- Testing
- Incretins
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Study on the Function of Taiwan Green Propolis in Reducing Blood Lipids and Body Fat in Sub-healthy Groups: MASLD
This study investigates the effectiveness of Taiwanese green propolis in reducing blood lipids and body fat in sub-healthy individuals.
- Trial name
- TGP (NCT07114926)
- Testing
- Taiwanese green propolis
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kuo,HSIN-YU
Energy Expenditure, Substrate Oxidation
Helichrysum Italicum Infusion Ingestion in Humans
The study evaluates the acute effects of Helichrysum italicum on resting energy expenditure and substrate oxidation in humans. The resting energy expenditure and substrate oxidation will be measured by indirect calorimetry at…
- Conditions
- Energy Expenditure, Substrate Oxidation, Blood Pressure
- Trial name
- SMILJ (NCT04818905)
- Testing
- Helichrysum italicum infusion, Hot water
- Where
- Slovenia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Healthy
Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels
In this study, the investigators address the research question of whether palm olein will have a positive influence on plasma total homocysteine levels in human volunteers provided with high-protein diets formulated from common…
- Trial name
- NCT00941837
- Testing
- Olive Oil, Palm Olein Oil, Coconut Oil
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Healthy Volunteers
Assessing the Safety, Tolerability and Pharmacokinetics(PK) of DZD9008 and the Effect of Low-fat Meal on PK of DZD9008 in Healthy Adult Participants
This is a Phase 1, randomised, double-blind, placebo-controlled, single ascending dose sequential group study in healthy participants.
- Trial name
- NCT04909242
- Testing
- DZD9008
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Dizal Pharmaceuticals
Healthy
The Relationship Between Body Composition and Growth Hormone, SIRT Signaling, Protein Turnover and Insulin Sensitivity
The purpose of this study is to investigate signaling pathways in fat and muscle, as well as turnover of protein, sugar and fat after stimulation with growth hormone and during fasting in lean and obese subjects.
- Trial name
- NCT01299831
- Testing
- 72 hour fast, control, 12 hour fast, Growth hormone
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alveolar Bone Loss
Effect of Buccal Fat Pad Derived Stem Cells in Maxillary Sinus Augmentation
In this study the buccal fat pad derived stem cells (BFPSCs) will be harvested from buccal fat pad tissue of patients receiving maxillary sinus augmentation.
- Trial name
- NCT02745379
- Testing
- BFPSCs+ DFDBA+ PRF, DFDBA + PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Micromastia, Breast Ptosis
Autologous Fat Grafting to the Breast
Structural fat grafting is a form of tissue transfer where the autologous fat is harvested and subsequently transferred to a different region of the body at the same setting.
- Conditions
- Micromastia, Breast Ptosis, Implant Failure, Breast Reconstruction
- Trial name
- NCT00775788
- Testing
- Autologous Fat Grafting to Breasts
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Lateral Gluteal Depression
Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study
Primary Objective: use immunofluorescence (IF) on previously obtained biopsies to analyze and quantify changes in adipose tissue of subjects injected with poly-L-lactic acid (PLLA) or saline.
- Trial name
- NCT06656923
- Testing
- Biopsies
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Obesity
Fish Oils and Adipose Inflammation Reduction
This study is a clinical trial designed to assess whether fish oil treatments are effective in the prevention of obesity-related fat tissue (adipose) inflammation.
- Trial name
- FAIR (NCT02010359)
- Testing
- Lovaza
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity
Protein and Resistance Exercise to Stop Sarcopenic Obesity Now
The purpose of this study is to examine the separate and combined effects of a high-protein (HP) diet and resistance training (RT) on body composition and potential biological moderators of body weight in women and men >50y.
- Trial name
- PRESS ON (NCT04014296)
- Testing
- High Protein Diet Counseling, Resistance Training Counseling, Intensify Initial Intervention
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obstructive Sleep Apnoea, Obesity
Obstructive Sleep Apnoea and Adipose Tissue Dysfunction
Dysfunctional adipose tissue predisposes to cardiovascular disease. Similarly, the risk of cardiovascular disease appears to be increased in subjects with obstructive sleep apnoea.
- Conditions
- Obstructive Sleep Apnoea, Obesity, Hypoxia
- Trial name
- NCT02518633
- Testing
- Continuous positive airway pressure devices
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Diabetes, Exercise Physiology
Elevated FFA and Skeletal Muscle Lipid Content
There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events.
- Trial name
- NCT01906333
- Testing
- Exercise, Glucose, Fasted
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Overweight
Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
The purpose of the study is to determine whether calcium plus vitamin D supplementation is conducive to weight and fat loss during energy restriction in very-low calcium consumers.
- Trial name
- NCT01447433
- Testing
- Calcium Carbonate, Energy restriction
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Obesity
Nicotinamide Riboside and Mitochondrial Metabolism
Vitamin B3 has recently been found to be a potent modifier of energy metabolism, especially the function of mitochondria. Mitochondria power up all cells in our bodies, by generating fuel, ATP, for cellular functions.
- Trial name
- VitaPower (NCT03951285)
- Testing
- NR in BMI-discordant twins, NR in BMI-concordant twins
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Healthy
Impact of Single Exercise Session Conducted Prior to PKU Type Meal on Appetite Hormones and Energy Intake
The study applied a randomized, crossover design with preliminary (screening) session and two sequenced experimental trials. Trials were marked as Control trial and Exercise trial.
- Trial name
- NCT04302285
- Testing
- PKU type meal and Exercise, PKU type meal
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Focus: Understanding the Obesogenic Potential of Sugars and Non-caloric Sweeteners
The Effect of Sugar Sweetened and Diet Beverages Consumed as Part of a Weight-Maintenance Diet on Fat Storage
The purpose of this study is to investigate the effects of consumption of sugar sweetened and diet beverages on overall fat mass and the fat mass of various tissues implicated in the dysregulation of glucose metabolism.
- Trial name
- NCT02252952
- Testing
- Beverage Consumption
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Human Immunodeficiency Virus, Obesity
Adipose Tissue and Immune Activation in HIV
The prevalence of HIV-associated wasting declined dramatically with the introduction of effective antiretroviral therapy (ART), but as patients survive longer on treatment the proportion of overweight (body mass index [BMI] >25…
- Trial name
- AIAC (NCT04439448)
- Testing
- dual-energy X-ray absorptiometry (DEXA) scan, Carotid and branchial artery ultrasound, 2-hour oral glucose tolerace test
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Abdominal Fat
Comparison of the Effects of Electric Current With Needles and Surface Electrodes on the Abdominal Contour of Women
The goal of this clinical trial is to compare the acute effects of percutaneous and transcutaneous eletroclipolysis on abdominal contour in women.
- Trial name
- NCT05973526
- Testing
- Percutaneous Electrolipolysis, Transcutaneous Electrolipolysis
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Ageing Well, Neuromuscular Function
Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Healthy, Recreationally Active Adults
The main aim of this study is to understand if chronic supplementation (12 weeks) of a milk fat globule membrane containing supplement, called bioactive whey protein concentrate, improves human muscle function greater than a…
- Trial name
- NCT06573749
- Testing
- Bioactive whey protein concentrate, Whey protein isolate supplement
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Loughborough University
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