Clinical trials: Body Fat
Obesity
Study of Efficacy of a Probiotic and Postbiotic in Overweight and Obese Individuals
The study's main objective is to investigate the effect of a probiotic (live bacteria), postbiotic (heat-treated bacteria) on obesity parameters.
- Trial name
- Obelix (NCT05440630)
- Testing
- Probiotics, Postbiotic
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Hypercholesterolemia
Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women.
The purpose of this study is to determine whether snacks differing in fat amount and type result in changes in cardiovascular disease risk factors in men and women who have mildly elevated cholesterol levels.
- Trial name
- NCT00349765
- Testing
- higher fat, high polyunsaturated fat diet, higher fat, high saturated and trans fat diet, lower fat diet
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Intermuscular Adipose Tissue Quantification
Impact of Muscle Fat Accumulation on the Genomic Profile of Skeletal Muscle in Older Adults
Subjects were asked to come to the Purdue facilities after an overnight fast on 2 different testing days for 2.5 hours each day.
- Trial name
- NCT02187965
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Evaluation of the Accuracy of a Computer Vision-based Tool for Assessment of Total Body Fat Percentage
This research study is designed to validate the precision and accuracy of body measurement and composition results from a novel 2D imaging device that operates through a smart-phone application.
- Trial name
- MEASURE (NCT04854421)
- Testing
- VBC
- Where
- 2 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Lateral Gluteal Depression
Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study
Primary Objective: use immunofluorescence (IF) on previously obtained biopsies to analyze and quantify changes in adipose tissue of subjects injected with poly-L-lactic acid (PLLA) or saline.
- Trial name
- NCT06656923
- Testing
- Biopsies
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Healthy, Metabolic Syndrome
Effect of Cherry Juice on Fat Oxidation and Cardio-metabolic Markers
The present study examined the effect of Montmorency tart cherry juice and FATMAX (intensity eliciting maximal fat oxidation) exercise on fat oxidation rates, body composition and blood-based cardio-metabolic markers.
- Trial name
- NCT02999256
- Testing
- Montmorency Tart Cherry Juice
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Body Fat Disorder
Non-Invasive Reduction of Fat in the Inner Thighs
Evaluate the safety and efficacy of non-invasive fat reduction in the inner thighs with the ZELTIQ CoolSculpting System.
- Trial name
- NCT01517659
- Testing
- The Zeltiq CoolSculpting System
- Where
- 3 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Healthy
Effect of a High-fat Meal on the Pharmacokinetics of Hetrombopag and Mass Balance Study in Healthy Subjects
This open-label, randomized, two-period, two-treatment (single doses of 7.5 mg hetrombopag fasted or fed), crossover study was conducted to evaluate the effect of a high-fat meal on the pharmacokinetics of hetrombopag and mass…
- Trial name
- NCT02409394
- Testing
- Hetrombopag Olamine
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Energy Metabolism, Athletic Performance
Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation
Maximal fat oxidation during exercise (MFO) and the intensity of exercise that elicits MFO (Fatmax) has been recognized as potential determinants of endurance performance.
- Trial name
- NCT04320446
- Testing
- Test in the morning, Test in the afternoon
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Obesity, Insulin Resistance
Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health
The purpose of this study is to understand how weight loss by a very low fat plant-based diet with an exercise program affects metabolic and cardiovascular health in overweight adults at high risk for disease.
- Trial name
- PE (NCT02706288)
- Testing
- Weight loss with very low fat plant-based diet and regular exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Mildly Hypercholesterolemic Subjects
Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (France)
The purpose of this study is to investigate the effect on cholesterolemia profile of a low fat fermented milk enriched with plant sterol after 3 and 6 weeks of daily consumption in mildly hypercholesterolemic people treated or…
- Trial name
- NCT01574469
- Testing
- 1-Low fat fermented dairy product enriched with plant sterol esters (0,8 g equivalent as free sterols) (test), 2-Low fat fermented dairy product (control)
- Where
- France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Breast Fat Grafting Retention
AuraClens™ System in Processing of Lipoaspirate for Autologous Fat Grafting to the Breast
Prospective, multi-center, non-randomized, open-label, post-market clinical study evaluating adipose graft retention over time from lipoaspirate processed using the AuraGen 1-2-3™ with AuraClens™ Lipoaspirate Wash System.
- Trial name
- AuraGen (NCT05258305)
- Testing
- AuraGen 1-2-3 with AuraClens
- Where
- 14 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tiger Biosciences, LLC.
Hyaluronic Acid, Fat Graft
Clinical Evaluation of Interdental Papilla Reconstruction Using Injectable Autogenous Fat Versus Hyaluronic Acid Filler.
The goal of this randomized controlled trial is to evaluate the amount of interdental papilla fill following the injection of the fat graft compared to hyaluronic acid filler in patients with interdental papilla deficiency.
- Trial name
- NCT05579522
- Testing
- Fat graft injection, Hyaluronic acid injection
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiometabolic Health
The InterSat Study
In response to the removal of trans fats from our foods, the food industry now uses interesterified (IE) fats. Randomly interesterified (IE) fats rich in palmitic (Europe) and stearic (North America) acids are the most commonly…
- Trial name
- InterSat (NCT04418102)
- Testing
- Palmitic acid rich interesterified fat, Stearic acid rich interesterified fat
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King's College London
Insulin Resistance, Obesity
Adipose Tissue Response to Overfeeding in Insulin Resistance-Prone vs. Insulin Sensitive Humans
Obesity has become an epidemic worldwide. Data from our laboratory and others demonstrate that most of the excess morbidity from obesity is related to insulin resistance (IR).
- Trial name
- NCT02084641
- Testing
- Over feeding
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Diabetes
Differential Metabolism of Dietary Fatty Acids
Differences in how diet fats are converted to energy could explain some of the reported differences in health effects among different classes of dietary fat (e.g. monounsaturated vs. saturated).
- Conditions
- Obesity, Diabetes, Hyperlipidemia
- Trial name
- NCT00059254
- Testing
- Oleic acid (OA), Palmitic Acid (PA)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Subcutaneous Fat
A Phase 1 Study to Evaluate the Safety and Tolerability of CBL-514 Injection on Convexity or Fullness of Abdominal Subcutaneous Fat in Healthy Volunteers
The Phase 1 component of the study is a double-blind, placebo-controlled, single ascending dose (SAD) design intended to assess the safety, tolerability, and PK of CBL-514. The SAD part will involve 9 proposed dosing cohorts.
- Trial name
- NCT04699669
- Testing
- CBL-514
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Breast Feeding
Newborn Feeding and Infant Phenotype
Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism.
- Trial name
- NCT02033005
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Endothelial Dysfunction
The Acute Effects of Commercially Available Drinks on the Endothelial Function of Humans Following a High-fat Meal
High fat diets are associated with impaired endothelial function and increased cardiovascular disease risk amongst our population.
- Trial name
- NCT03806829
- Testing
- Water, Red Wine, Green Tea
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of the Highlands and Islands
Overweight, Risk Behavior
Fasting-mimicking Diet and Longevity Diet, Body Composition and Aging
This study was designed as a large, randomized, controlled clinical trial in a heterogeneous population and is aimed at assessing as a primary objective whether the fasting-mimicking diet alone or in combination with the…
- Conditions
- Overweight, Risk Behavior, Obesity
- Trial name
- NCT05698654
- Testing
- Fasting-mimicking diet (FMD), Longevity Diet (LD) + Fasting-mimicking Diet (FMD)
- Where
- Italy
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo