Clinical trials: Body Fat
Dravet Syndrome
Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.
This is a placebo-controlled, double-blind, 2-period study in 3 sequential groups of 8 healthy subjects each. The safety and pharmacokinetics of escalating single and multiple oral doses of EPX-100 will be assessed in fasting…
- Trial name
- NCT04069689
- Testing
- EPX-100 (Clemizole Hydrochloride)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Epygenix
Excess Abdominal Fat
UltraShape Power for Abdominal Fat and Circumference Reduction
Prospective, one arm, baseline-controlled, clinical study for the evaluation of the UltraShape Power treatment using the U-Sculpt Power Transducer for non-invasive abdominal fat and circumference reduction.
- Trial name
- NCT02748928
- Testing
- UltraShape Power
- Where
- 8 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Obesity
Craving and Lifestyle Management Through Mindfulness Study
The purpose of this study is to determine whether a mindfulness-based stress reduction and mindful eating program will lead to reductions in abdominal fat and total weight and improve cell aging in overweight and obese women…
- Trial name
- CALMM (NCT01250509)
- Testing
- Craving and Lifestyle Management through Mindfulness
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity
The Effect of Calcium on Fecal Fat and Energy Excretion
The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.
- Trial name
- NCT00519909
- Testing
- Dairy calcium
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Steatosis of Liver
Comparison of MRI-PDFF to TAEUS FLIP Device to Estimate Liver Fat Fraction in Adults
Primary nonalcoholic fatty Liver disease (NAFLD) is an excess of fat in the liver (steatosis) that is not a result of excessive alcohol consumption or other secondary causes11.
- Trial name
- NCT06373536
- Testing
- Thermoacoustic imaging, MRI and Ultrasound imaging
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Endra Lifesciences
Obesity
mTOR and Adipose Tissue Inflammation
The target of rapamycin complex 2 (TORC2) is an evolutionarily conserved serine/threonine protein kinase that controls growth and metabolism.
- Trial name
- NCT02881697
- Testing
- Adipose tissue sampling
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Fat Taste
Sour Taste Intensity Matching With Fatty Acids Taste
Investigators are trying to find the concentrations of fatty acids ( a part of the fat and flavor typically found in normal foods) that have a taste intensity similar to that to the sourness of vinegar solutions.
- Trial name
- NCT04245488
- Testing
- taste test
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Purdue University
Body Fat Disorder
DualSculpting the Abdomen Using CoolSculpting
Evaluate the safety and efficacy of abdominal DualSculpting with CoolAdvantage applicators.
- Trial name
- DSA (NCT02941146)
- Testing
- The ZELTIQ System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity
Effect of Intake of Glycin Max (L.) Merr. Peel Extract on Body Fat and Body Weight
The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Glycin max (L.) Merr. peel extract on decrement of body fat.
- Trial name
- NCT02108691
- Testing
- Glycin max(L.) Merr. peel extract
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Healthy Participants
A Clinical Trial to Evaluate the Effect of Food on the Pharmacokinetics of Ammoxetine Hydrochloride Enteric-coated Tablets in Healthy Subjects
This study is a single-dose, randomized, open-label, three-sequence, three-period crossover clinical trial to evaluate the effect of high-fat and low-fat meals on the pharmacokinetics of ammoxetine hydrochloride enteric-coated…
- Trial name
- NCT07508462
- Testing
- Ammoxetine hydrochloride enteric-coated tablets
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Mild Hypercholesterolemic Subjects
Effect of the Consumption of a Fermented Dairy Product Enriched With Plant Sterols
The purpose of this study is to investigate the cholesterol lowering effect of a drinkable low fat fermented milk enriched with plant sterols after 3 weeks of daily consumption in midly hypercholesterolemic people.
- Trial name
- NCT01521156
- Testing
- 1- low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols)., 2- low-fat dairy fermented product (drinkable) enriched with experimental plant sterols-esters (1,6g /day equivalent as free sterols).
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Healthy
A Study of Doravirine and Islatravir as a Single Entity or Combination Therapy and the Effect of Food in Healthy Adult Participants (MK-8591A-055)
The purpose of this study is to learn what happens to MK-8591A in a person's body over time. Researchers will compare what happens to MK-8591A in the body when it is given with and without food.
- Trial name
- NCT06719570
- Testing
- MK-8591A, Islatravir, Doravine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2, NASH - Nonalcoholic Steatohepatitis
Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver
This randomized clinical trial aims to compare the effect of the pioglitazone and SGLT2 inhibitor combination on liver fat mass, as compared to either drug used alone, with or without background medical therapy of metformin…
- Conditions
- Diabetes Mellitus, Type 2, NASH - Nonalcoholic Steatohepatitis, NAFLD
- Trial name
- NCT04976283
- Testing
- Pioglitazone, Empagliflozin, Pioglitazone + Empagliflozin
- Where
- Pakistan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Abdominal Obesity
Combination of Cryolipolysis and Aerobic Exercise in Reducing Abdominal Fat
The purpose of the study is To investigate the adding effect of Cryolipolysis to aerobic exercise with low caliorie diet on waist-to-hip ratio , ultrasonography, body mass index and skin fold of subcutaneous fat tissue in…
- Trial name
- NCT05852652
- Testing
- cryolipolysis and aerobic exercise
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Body Fat
Effects of Lipoic Acid and Eicosapentaenoic Acid (EPA) in Human Obesity
The aim of the study is to analyze the effects of Lipoic acid and/or EPA supplementation on weight loss, lipid profile, insulin resistance, oxidative and inflammation parameters, metabolomic profile as well as on adipose tissue…
- Conditions
- Obesity, Body Fat, Insulin Resistance
- Trial name
- OBEPALIP (NCT01138774)
- Testing
- Double blind dietary intervention with EPA and lipoic acid
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Precursor Cell Lymphoblastic Leukemia-Lymphoma, Vitamin D Deficiency
Nutrition and Body Composition in Acute Lymphoblastic Leukemia
Many adolescents with acute lymphoblastic leukemia (ALL) have been found to have low bone density by the end of treatment. This can lead to long-term suffering in survivors due to poor bone health.
- Trial name
- NCT01317940
- Testing
- Vitamin D and Calcium Citrate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Lipid-induced Insulin Resistance
Fat and Transcapillary Insulin Transport
There is a current debate whether impaired insulin-mediated microvascular perfusion limits the delivery of hormones and nutrients to muscle and whether short term FFA elevation affects transcapillary transport of insulin and…
- Trial name
- FATRAIN (NCT01482455)
- Testing
- Elevation of FFA during OGTT, Elevation of FFA during Clamp
- Where
- Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Body Fat Disorder
Effects on Cellulite Appearance
Evaluate the safety and feasibility effecting the appearance of cellulite on the thigh using CoolSculpting.
- Trial name
- EFC (NCT04876118)
- Testing
- The ZELTIQ System
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Infant
Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development
Formula-fed infants differ from breast-fed infants in the growth pattern, risk for obesity and cardiovascular diseases, neurological development and morbidity in infections.
- Trial name
- TUMME (NCT00624689)
- Testing
- Modified formula (MFGM-enriched formula with reduced energy and protein content)
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Umeå University
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