Clinical trials: Body Fat
Effect of Diet on Microbiome Composition
Controlled Feeding Experiment
The purpose of this study is to determine the effect of dietary fat, in standard formulation, on the composition of the human microbiome in a prospective study of normal volunteers.
- Trial name
- CaFE (NCT00951756)
- Testing
- High fat diet
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- James Lewis
Healthy
Bioavailability of BI 44370 TA Drinking Solution or Tablets With and Without a High Fat Meal in Healthy Male and Female Volunteers
The objective of this trial was to evaluate the relative oral bioavailability and pharmacokinetics of BI 44370 TA drinking solution (100 mg and 200 mg) and BI 44370 TA tablets (100 mg as two 50 mg tablets) with and without a high…
- Trial name
- NCT02215746
- Testing
- BI 44370 powder for oral solution, BI 44370 tablet, high fat breakfast
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Unilateral Cleft Lip
Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair.
- Trial name
- NCT04735237
- Testing
- Autogenous fat injection, Surgical revision with orbicularis oris muscle reconstruction.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Augmentation
Improved Breast Enlargement Using the Subject's Own Fat Tissue
The goal of this clinical study is to learn if the Medical Device Under Investigation (simply "the device") is safe to use in human adults undergoing breast augmentation surgery.
- Trial name
- SWIFT (NCT07869641)
- Testing
- An injectable, biodegradable hydrogel, in reconstitution medium, Reconstitution medium
- Where
- 2 sites in Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- 4Tissue
HIV Infections, Insulin Resistance
Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance
The purpose of this study is to determine if, in men and women with excess abdominal fat and insulin resistance, people with HIV infection respond differently than people without HIV to interventions that typically improve body…
- Conditions
- HIV Infections, Insulin Resistance, Obesity
- Trial name
- NCT00264251
- Testing
- Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Insulin Resistance, Metabolic Syndrome
Gene Expression in Obesity and Insulin Resistance
Lifestyle and genetic factors interact in the development of obesity and the metabolic syndrome. The molecular mechanisms underlying the beneficial dietary modifications are, however, unclear.
- Trial name
- Genobin (NCT00621205)
- Testing
- Weight reduction, Resistance training, Aerobic exercise training, Control
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Exercise-related Amenorrhea
Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes
One aim of this study is to determine changes in body composition and hormones that differentiate athletes who stop getting their periods versus those who continue to get their periods and non-athletes.
- Trial name
- NCT00946192
- Testing
- Transdermal 17Beta-estradiol, progesterone, Ethinyl Estradiol + Desogestrel
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Type 2 Diabetes Mellitus
Brown Adipose Tissue and Body Mass Index
In this study the investigators aim to investigate whether the sympathetic stimulation of BAT, as assessed with a 123I-metaiodobenzylguanidine single-photon emission computed tomography computed tomography scan, differs between…
- Trial name
- NCT02173834
- Testing
- 18F- fluorodeoxyglucose-positron emission tomography Computed Tomography scan and 123I-metaiodobenzylguanidine-single-photon emission computed tomography scan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NAFLD
Understanding the Role of Dietary Fatty Acids on Liver Fat Metabolism in Humans
High levels of fatty substances in the blood increase the risk of developing heart disease. Investigators know a lot about one of these fatty substances, cholesterol.
- Trial name
- NCT01936779
- Testing
- Dietary supplement: fatty acid
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Prevention
Study on the Effectiveness of a School-Based Fat Loss Program for Adolescents
The students were divided into an intervention group and a control group. The intervention group attended fat loss exercise classes three times a week and the parents cooperated with us in dietary monitoring and control.
- Trial name
- NCT06524908
- Testing
- Exercise and dietary calorie restriction
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Cardiovascular Risk Factor, Lipemia
Effect of Galactose Ingestion on Postprandial Lipemia
This study aims to assess the postprandial triglyceride response to the ingestion of a high-fat meal with co-ingestion of either galactose, or glucose.
- Trial name
- NCT03439878
- Testing
- Galactose, Glucose
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bath
Elevated Triglycerides, Diabetes
Change of Fructose to Fat in South Asians
The purpose of this study is to determine whether hepatic de novo lipogenesis (DNL) in response to the ingestion of a mixture of glucose and fructose is greater in South Asians compared to controls (Caucasians).
- Conditions
- Elevated Triglycerides, Diabetes, Cardiovascular Disease, Dyslipidemia
- Trial name
- NCT01562782
- Testing
- Fructose + Glucose Beverage
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- The Rogosin Institute
Healthy Volunteers
FBCx (Alpha-CD) Mechanism of Action Trial
To determine the fat losses in stool associated with alpha-CD use in healthy volunteers, as compared to placebo when consumed with a standardized radiolabeled fatty meal.
- Trial name
- FMAT (NCT02999620)
- Testing
- Alpha-cyclodextrin
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- SFI Research
Diet Modification
Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism
The purpose of this study is to compare the effect of ingesting caffeine and mixed flavonoids (4 capsules, split between breakfast and lunch) on energy expenditure and fat oxidation in a metabolic chamber with 20 women…
- Trial name
- NCT03752125
- Testing
- Flavonoid, caffeine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Subcutaneous Fat Disorder
Subject Evaluation of a 1064nm Diode Laser/RF
Open-label, baseline-controlled, multi-center study evaluating a 1064 nm diode laser, pulsed electromagnetic fields and vacuum assisted radio frequency for non-invasive fat reduction of the abdomen and flanks.
- Trial name
- NCT04090853
- Testing
- Venus Bliss
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Venus Concept
Urinary Incontinence,Stress
Fat Grafting Technique Using Autologous Adipose Tissue Lipogems in Patients Suffering From Stress Urinary Incontinence
Urinary incontinence affects more than 200 million people worldwide. In women, childbirth or menopausal aging atrophic vagina, lack of estrogen stimulation of muscular turgor of the vagina, decrease tone of the urogenital…
- Trial name
- NCT03295253
- Testing
- Autologous adipose tissue harvesting/grafting using Lipogems
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Cardiometabolic Health
The InterSat Study
In response to the removal of trans fats from our foods, the food industry now uses interesterified (IE) fats. Randomly interesterified (IE) fats rich in palmitic (Europe) and stearic (North America) acids are the most commonly…
- Trial name
- InterSat (NCT04418102)
- Testing
- Palmitic acid rich interesterified fat, Stearic acid rich interesterified fat
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King's College London
Safety
A Clinical Study to Evaluate the Safety, Pharmacokinetic Profile and Efficacy of CU-20401
This study is a Phase Ib/II clinical study. Phase 1b was a single-center, nonrandomized, single-arm study to evaluate the safety, PK profile, preliminary efficacy, and immunogenicity of different groups (SC) of CU-20401 in the…
- Trial name
- NCT05195541
- Testing
- CU-20401
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cutia Therapeutics（Wuxi）Co.,Ltd
Metabolic Syndrome, Obesity
Epicardial Fat Thickness and Inflammation in People With Metabolic Syndrome and Obesity
Epicardial adipose tissue (EAT) is a type of visceral adipose tissue (VAT), functioning as a metabolically active endocrine organ and suggested to play an important role in the progression of metabolic syndrome (MetS).
- Conditions
- Metabolic Syndrome, Obesity, Inflammation
- Trial name
- NCT04437979
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Obesity, Abdominal
Microcurrent and Aerobic Exercise Effects in Abdominal Fat
The purpose of this study was to analyze microcurrent short term effects used with aerobic exercise on abdominal fat.
- Trial name
- NCT02110927
- Testing
- Transcutaneous microcurrent, Aerobic exercise
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.