Clinical trials: Body Fat
Flanks Fat Reduction vs. Control
Fat Reduction in the Flanks Area vs. Control
Prospective, blinded, one arm, baseline-controlled clinical study for the evaluation the performance of the UltraShape treatment for non-invasive fat reduction by compare control and treated flanks.
- Trial name
- NCT02465775
- Testing
- UltraShape treatment
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Urinary Incontinence,Stress
Fat Grafting Technique Using Autologous Adipose Tissue Lipogems in Patients Suffering From Stress Urinary Incontinence
Urinary incontinence affects more than 200 million people worldwide. In women, childbirth or menopausal aging atrophic vagina, lack of estrogen stimulation of muscular turgor of the vagina, decrease tone of the urogenital…
- Trial name
- NCT03295253
- Testing
- Autologous adipose tissue harvesting/grafting using Lipogems
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity, Type 2 Diabetes Mellitus
The Influence of Fatty-Acids on Systemic and Subcutaneous Cytokines
This is a mono-center randomized controlled trial to be performed in the Center of Medical Research (ZMF) at Medical University Graz and is composed by one screening visit (V1) and two study visits (V2 and V3).
- Trial name
- TNF4 (NCT00708266)
- Testing
- Openflow microperfusion catheter, Intralipid 20%, 0.9% Saline Solution
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Sperm Quality, Obesity
Obesity With Sperm Quality in Men With Fertility Need
This study aims to investigate the impact of different types of obesity on sperm quality. Participants will be divided into three groups: a normal BMI group, an obese group without pudendal fat wrapping the testicles, and an…
- Conditions
- Sperm Quality, Obesity, Sex Hormones, Visceral Fat
- Trial name
- NCT06353880
- Testing
- Participants will be categorized into three groups based on BMI and the presence of pudendal fat deposition.
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yu xiaowei
Post Herpetic Neuralgia, Herpes Zoster
Treatment of Chronic Postherpetic Pain With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post herpetic neuralgia.
- Trial name
- NCT03584061
- Testing
- Fat grafting
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Healthy Volunteers
A Study of ENX-104 in Healthy Participants
The study is designed to evaluate the relative bioavailability, safety, and tolerability of a single dose of ENX-104 administered orally as a solution fasted, a tablet fasted, or a tablet with a high fat meal in healthy…
- Trial name
- NCT07472361
- Testing
- ENX-104
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Engrail Therapeutics INC
Obesity, Exercise
Exercise Training and Insulin Sensitivity
Regular exercise participation is known to reduce cardiometabolic disease risk but the impact that exercise training has on adipose tissue (AT) metabolism is poorly understood, particularly in humans.
- Trial name
- NCT05930834
- Testing
- exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Abdominal, Feeding Patterns
Circadian Rhythms in Human Adipose
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
- Trial name
- NCT06891534
- Testing
- Continuous Feeding, Intermittent feeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Laser Assisted Liposuction
Laser Assisted Liposuction and Facial Autologous Fat Grafting With the LipoLife System
Multi-center, prospective, open-label, single arm study. The study aims to evaluate the safety and efficacy of Laser Assisted Liposuction procedure performed with the LipoLife system.
- Trial name
- NCT03800563
- Testing
- LipoLife system
- Where
- 2 sites in United States, Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
NAFLD, Overweight and Obesity
The Acute Effects of Eucaloric and Hypocaloric Carbohydrate Restriction on Liver Fat Content and Metabolism in Obese Individuals
The primary aim of this study is to investigate the acute changes in liver fat content in response to a fixed carbohydrate restriction (i.e.
- Conditions
- NAFLD, Overweight and Obesity, Metabolic Syndrome, Diabetes
- Trial name
- FixedCarb (NCT05643521)
- Testing
- Dietary composition of macronutrients and calories
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus Type 2, Heart Failure
Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences
This will be an observational study to explore differences in pathophysiology between groups of people with and without heart failure (HF) (reduced and preserved ejection fraction) and with and without diabetes mellitus (DM) with…
- Conditions
- Diabetes Mellitus Type 2, Heart Failure, HFrEF - Heart Failure With Reduced Ejection Fraction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT06774014
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity
Influence of Male Hormones on Regional Fat Metabolism
The male sex hormone, testosterone, plays an important role in determining body fat distribution in men. This is especially evident in the dramatic shift in body composition as boys and girls reach sexual maturity.
- Trial name
- NCT01160328
- Testing
- Leuprolide, Testosterone
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
Effect of Dietary Components on Gastrointestinal Side Effects Induced by Orlistat, a Lipase Inhibitor
The objective of the Orlifat trial is to investigate if dietary fibres from linseeds and dairy calcium (Capolac ®) may reduce gastrointestinal side effects related to increased fecal fat content, induced by treatment with Alli®…
- Trial name
- ORLIFAT (NCT01320228)
- Testing
- Control, Capolac, Flax fiber
- Where
- Denmark
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Skin Laxity
Safety and Efficacy of the BTL-785F Device for Non-invasive Reduction of Submental Fat
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive reduction of submental fat and skin laxity treatment.
- Trial name
- NCT05831332
- Testing
- BTL-785-7
- Where
- Bulgaria
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Obese
Metabolism Associated With Abdominal Fat Mass Distribution
Objectives: The primary objective of this clinical trial is to characterize metabolic signatures associated with abdominal fat distribution in 40 women with different BMI 29-40 and different abdominal distribution of fat…
- Trial name
- NCT01726647
- Where
- 2 sites in Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Behaviour
The Dietary Intervention in e-Shopping Trial
The supermarket industry now services many customers through online food shopping over the Internet. The Internet shopping process offers a novel opportunity for the modification of dietary patterns.
- Trial name
- NCT00352508
- Testing
- Dietary advice
- Where
- Australia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The George Institute
Gastrointestinal Hormones
Impact of Macronutrient Composition of Energy-restricted Diet and Exercise on Body Composition and Appetite Hormones.
The main aim of this study is to investigate the effect of energy-restricted low and high-carbohydrate diet combined with exercise training on appetite regulatory hormones, subjective appetite and energy intake in overweight and…
- Trial name
- NCT06022315
- Testing
- caloric restrction high carbohydrate low fat diet with exercise training program, caloric restrction high fat low carbohydrate diet with exercise training program
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Infection, Human Immunodeficiency Virus
A Study to Evaluate the Effect of High Fat Meal on Cabotegravir
Cabotegravir is being developed for the treatment of human immunodeficiency virus (HIV) 1 infection. Specifically, it is being developed as a component of a 2-drug maintenance regimen (post-induction of viral suppression) that…
- Trial name
- NCT02799264
- Testing
- Cabotegravir 30 mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Obesity
The Significance of Vitamin D Storage in Adipose Tissue
The study will examine the role of adipose tissue in vitamin D physiology, particularly its role as a depot. the study is randomized double blind and placebo controlled.
- Trial name
- NCT01728987
- Testing
- cholecalciferol
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tromso
Obesity, Social Dominance
Subjective Social Status and Energy Balance
Investigators examined the associations between SSS, energy balance, food intake and changes in body composition following a high calorie lunch for 2 weeks.
- Conditions
- Obesity, Social Dominance, Social Behavior, Eating Behavior
- Trial name
- NCT03510364
- Testing
- Dietary intervention
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Texas Tech University