Clinical trials: Body Fat
Ageing, Mitochondrial Function
The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans
The aim of this study is to determine whether dairy or plant based fats combined with fish oils can alter skeletal muscle mitochondrial, physical, and cognitive function.
- Conditions
- Ageing, Mitochondrial Function, Physical Function, Cognitive Function
- Trial name
- NCT04194983
- Testing
- Fish oils and dairy fat, Fish oils and plant fat
- Where
- 2 sites in Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Obesity, Normal Weigth
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
After eating, blood composition changes, including increased triglycerides and glucose, which can trigger postprandial inflammation. Particularly with high-fat foods, pro-inflammatory lipopolysaccharide (LPS) increases.
- Trial name
- CAPE (NCT06645756)
- Testing
- Test meal
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Healthy
"ADAPT" The Adaptation to High Fat Diets Extention
This study is designed to predict weight gain overtime after a high fat diet.
- Trial name
- NCT00493701
- Testing
- High Fat Diet, Low Fat Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 Diabetes
Offspring of patients with type 2 diabetes have increased risk of developing diabetes and are typically more insulin resistant than their peers with no diabetes family history.
- Trial name
- NCT00268541
- Testing
- Physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Pancreatic Steatosis, Pancreatic Cyst
Prevalence of Pancreatic Steatosis in Pancreatic Cystic Neoplasms and Pancreatic Adenocarcinoma
Several pancreatic neoplastic cystic lesions, such as IPMN (intrapapilary mucinous neoplasia), cystic neuroendocrine tumors (NET) and mucinous neoplasms, present a carcinogenetic risk, though it is yet unknown if this risk is…
- Conditions
- Pancreatic Steatosis, Pancreatic Cyst, Pancreatic Adenocarcinoma
- Trial name
- SPACE (NCT06867172)
- Testing
- computerized tomography, Endosonography (EUS)
- Where
- Romania
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Bichat's Fat Pad Atrophy, Facial Expression
Postoperative Evaluation of the Intraoral Technique of Buccal Fat Pad Removal
In recent years there has been a growing number of procedures for the removal of the buccal fat pad (BFP) or as frequently referred to as bichectomy.
- Trial name
- NCT03974373
- Testing
- BFP removal
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
Healthy
A Study in Healthy Men to Test Whether Food Affects the Amount of BI 894416 in the Blood
Investigate the relative bioavailability of BI 894416 as tablet formulation following a high-fat, high calorie breakfast (Test, T) compared with administration in the fasting state (Reference, R)
- Trial name
- NCT03871595
- Testing
- BI 894416
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Fat Embolism Syndrome
Incidence of Fat Embolism With Computer Assisted Total Knee Arthroplasty
The study to determine the if the incidence of Fat Embolism is decreased using Computer Assisted technology when performing a Total Knee Arthroplasty.
- Trial name
- Fat Embolism (NCT00656877)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marshall University
Healthy
Single Rising Dose Study to Assess Safety, Tolerability and Pharmacokinetics of BI 661051.
The objective of the current study is to investigate safety, tolerability, and pharmacokinetics of treatment with BI 661051 rising single doses administered as oral drinking solution (powder in bottle) in healthy male subjects.
- Trial name
- NCT01343719
- Testing
- BI 661051
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Rheumatoid Arthritis
Effect of a High-fat Meal on the Pharmacokinetics of SHR0302 and Mass Balance Study in Healthy Subjects
The purpose of this open-label, randomized, two-period, two-treatment (single doses of 10 mg SHR0302 fasted or fed), crossover study was to evaluate the effect of a high-fat meal on the pharmacokinetics of SHR0302 and mass…
- Trial name
- NCT02892370
- Testing
- SHR0302
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 1 Diabetes
Dietary Fat and Endothelial Function in Type 1 Diabetes
The purpose of this study is to evaluate the effects of the add-on of extra vergin olive oil or butter to a high glycemic index meal on endothelial function in subjects with type 1 Diabetes and healthy subjects.
- Trial name
- NCT04812782
- Testing
- EVOO supplementation, Butter supplementation
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Intra-Abdominal Fat
The Healthy Diet and Lifestyle Study II
Intermittent energy restriction (IER) may have important advantages over daily energy restriction (DER) in producing sustained weight loss and reducing cancer risk.
- Trial name
- (HDLS2) (NCT05132686)
- Testing
- IER+MED, MED/DER
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Food Effect in Healthy Participants
Evaluation of the Potential Impact of a High-fat Meal on the Pharmacokinetics of CRS3123 in Healthy Adult Participants
This study will explore the potential effects of high-fat meal on the plasma pharmacokinetics (PK) of CRS3123 when administered as a single oral dose of 200 mg in healthy adult participants.
- Trial name
- NCT06988423
- Testing
- CRS3123 200 mg capsule
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Crestone, Inc
Liver Fat, Type 2 Diabetes
EXIT: Prospective Study of the Response to Exercise
Background : Regular exercise is a cornerstone in the prevention and the management of comorbidities. Unfortunately, the metabolic benefit of exercise training is not universal and varies among individuals.
- Trial name
- EXIT (NCT02204670)
- Testing
- Acute release of irisin after a single exercise session.
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity
Weight Loss Composition and Metabolic Adaptation During Hypocaloric Dieting
Weight loss induced by hypocaloric dietary interventions is commonly accompanied by reductions in resting metabolic rate (RMR), a phenomenon often described as metabolic adaptation.
- Trial name
- NCT07627256
- Testing
- Hypocaloric Diet
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Obesity, Inflammation
Lean and Obese: Dietary Inflammation
In the Lean and Obese Dietary Inflammation (LODI) study, the primary goal is to determine the effect of short-term intake of high dietary fat (5 days) compared to low fat intake (5 days) in a cross-over design in older adults…
- Conditions
- Obesity, Inflammation, Dietary Fat
- Trial name
- LODI (NCT05327868)
- Testing
- Low Fat Diet (LFD), High Fat Diet (HFD)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Abdominal Obesity
Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes
In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, and risk of type 2 diabetes…
- Trial name
- NCT00739180
- Testing
- Control, Resistance Exercise, Aerobic exercise
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Overweight and Obesity, Elevated Triglycerides
A Trial to Assess Full-fat or Low-fat Dairy Foods on Insulin Sensitivity, RBC FA's and Other Markers of Metabolic Health
The objectives of this trial are to assess the effects of adding 2 servings/d of either full-fat or low-fat fermented dairy products to the diet, as a replacement for non-dairy foods with macronutrient composition similar to the…
- Trial name
- NCT04999462
- Testing
- Full-fat fermented dairy, Low-fat fermented dairy, Non-dairy, non-fermented foods
- Where
- 4 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Body Fat
The Trusculpt (Radio Frequency) Device For Thigh Circumference Reduction
The objective of this study is to evaluate the safety and efficacy of the Trusculpt (Radio Frequency) device in the reduction of thigh circumference.
- Trial name
- NCT01665118
- Testing
- Trusculpt (Radio Frequency) Device
- Where
- 3 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Obesity
Secretin Activates Human Brown Fat and Induces Satiation.
15 healthy males will be studied with PET/CT, using FDG to investigate glucose metabolism, and radiowater to investigate perfusion.
- Trial name
- GUTBAT (NCT03290846)
- Testing
- Secretin Human, Saline Solution, Cold exposure
- Where
- Finland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
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