Clinical trials: Body Fat
Healthy
Effects of Fasting and Exercise on Insulin and GH Signaltransduction in Muscle and Fat
Hypothesis: under fasting there will primarily be an activation of growth hormone(GH) signalpathways and a inhibition of insulin signalpathways, and the opposite will happen under physical activity.
- Trial name
- FEIGH (NCT00817440)
- Testing
- Exercise, Fasting
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lordosis
Analyze the Relationship Between the Density of Fat Tissue and Cellulite With the Lumbar Lordosis Degree
The aim of this study is analyze the relationship between the density of visceral and subcutaneous fat and cellulite with the lumbar lordosis degree.
- Trial name
- NCT02903459
- Testing
- Transversal Study so there is no intervention
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Healthy
A Study to Assess the Effect of a High Fat Meal on Surufatinib in Healthy Subjects
This study will be a 2-period study conducted with 26 healthy male or female subjects. Subjects will be randomly assigned to either receive a single dose of surufatinib with food in period 1, then without food in period 2, or…
- Trial name
- NCT04372394
- Testing
- surufatinib
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hutchison Medipharma Limited
Adipose Tissue Atrophy, Deformity of Reconstructed Breast
Effect of N-Acetylcysteine on Autologous Fat Graft Survival
A single-centre triple-blind study looking at the addition of NAC to tumescent solution for liposuction and fat grafting in healthy patient volunteers already undergoing bilateral breast reduction.
- Conditions
- Adipose Tissue Atrophy, Deformity of Reconstructed Breast, Graft Loss
- Trial name
- NCT02788292
- Testing
- Acetylcysteine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Overweight and Obesity
Evaluating the Efficacy of I-fiber Pearl on Reducing Body Fat Accumulation in Obese Subjects
The aim of this study is to investigate the effects of I-Fiber Pearl on Body Weight and Body Fat in Obese Adults.
- Trial name
- NCT06203834
- Testing
- I-Fiber Pearl
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Metabolic Syndrome
Efficacy of STABLOR® on Visceral Fat Mass Reduction in Patients With Metabolic Syndrome
The primary objective of the study is to assess the efficacy of STABLOR® consumption on visceral fat mass compared to placebo, in persons with metabolic syndrome during 12 weeks of consumption.
- Trial name
- OBEMINALE2 (NCT03692806)
- Testing
- Stablor
- Where
- 6 sites in France, Ireland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- LNC THERAPEUTICS
Vitamin D Deficiency
The Effect of Fat on Vitamin D Absorption
The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the…
- Trial name
- VITD_100484 (NCT01519986)
- Testing
- Vitamin D3
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Healthy
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects
The purpose of this trial is to demonstrate bioequivalence of a newly developed fixed dose combination (FDC) tablet containing empagliflozin and metformin extended release compared to the free combination of empagliflozin and…
- Trial name
- NCT02230995
- Testing
- metformin, empagliflozin/metformin, empagliflozin
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity
Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly
The purpose of this study is to determine the effect of weight loss and exercise on liver and muscle fat.
- Trial name
- NCT00779207
- Testing
- weight loss and exercise, weight loss
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency, Obesity
Vitamin D and Adipose Tissue Inflammation
Chronic, low-grade adipose tissue inflammation is a major risk factor for type 2 diabetes mellitus. The cause of adipose tissue inflammation has remained largely unclear.
- Conditions
- Vitamin D Deficiency, Obesity, Type 2 Diabetes Mellitus, Intestinal Permeability
- Trial name
- NCT01477034
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Skin Rejuvenation, Lipofilling
Effect of Adipose Derived Stem Cells on Survival of Fat as Filler
this research is to study the effect of Adipose Derived Stem Cells on Survival of Fat as Filler
- Trial name
- NCT03965936
- Testing
- lipofilling, lipofilling enriched with adipose tissue derived stem cells
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Age-related Macular Degeneration
Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration
The purpose of this study is to determine the relationship among the body fat distribution, especially the visceral fat, in patients with age-related macular degeneration in comparison to patients with a normal fundus.
- Trial name
- NCT01777984
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rudolf Foundation Clinic
Obesity, Abdominal, Feeding Patterns
Circadian Rhythms in Human Adipose
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
- Trial name
- NCT06891534
- Testing
- Continuous Feeding, Intermittent feeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Insulin Sensitivity
The Effect of 6 Weeks Saturated and Polyunsaturated High-Fat Diets on Insulin Sensitivity and Health Parameters
The aim of the intervention is to gain insight into the long term effect of dietary fatty acid quality on insulin sensitivity and health parameters in healthy men.
- Trial name
- NCT03561363
- Testing
- High-fat diet
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy Participants
A Study to Investigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants.
The main purpose of this study is to assess the effect of food on balcinrenone/ dapagliflozin pharmacokinetics in fed and fasted state and pharmacokinetics of balcinrenone when dosed with a P-gp inhibitor in healthy participants.
- Trial name
- NCT06979388
- Testing
- balcinrenone/ dapagliflozin, quinidine
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Aging
Bichectomy: Hydrodissection Technique
Buccal Fat Pad provides volume to the middle third of the face and occasionally may cause deepening of the nasolabial fold and relaxation of the mimetic muscles, both associated with aging.
- Trial name
- NCT03554499
- Testing
- Bichectomy with hydrodissection, Bichectomy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital General Dr. Ruben Leñero
Adipose Tissue, Brown, Brown Adipose Tissue
Cold Induced Activation of Brown Adipose Tissue in Humans
This study investigates cold-induced brown fat activation assessed using PET/MR scans. Subjects will participate in an acute cooling intervention day and a thermoneutral intervention day with PET/MR scans on both days.
- Conditions
- Adipose Tissue, Brown, Brown Adipose Tissue, Brown Fat, Uncoupling Protein 1
- Trial name
- COLDBAT (NCT03096535)
- Testing
- Cooling, Thermoneutral
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Susanna Søberg
Obesity
Effect of Specific Diet and Physical Activity on Weight and/or Fat Loss
The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low…
- Trial name
- NCT02325804
- Testing
- Lifestyle Counseling
- Where
- Slovakia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Obesity
A Study of the Efficacy of Subcutaneous Phosphatidylcholine and Deoxycholate Injections for Localized Fat Removal
The primary objective of this study is to determine the efficacy of phosphatidylcholine and deoxycholate subcutaneous injections for localized fat removal.
- Trial name
- NCT00851747
- Testing
- Phosphatidylcholine Deoxycholate, Saline
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Escherichia Coli Infections
Effects of Nutritional Fat on the Growth of Intestinal E. Coli
Recent experiments in the lab of Prof. WD Hardt revealed, that in mice, 24 h exposure to a high-fat diet results in a breakdown of colonization resistance against Salmonella typhimurium.
- Trial name
- NCT03800147
- Testing
- "Mutaflor Suspension" (E. coli Nissle 1917), Blood samples, Stool samples
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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