Clinical trials: Body Fat
Obesity
Study of Efficacy of a Probiotic and Postbiotic in Overweight and Obese Individuals
The study's main objective is to investigate the effect of a probiotic (live bacteria), postbiotic (heat-treated bacteria) on obesity parameters.
- Trial name
- Obelix (NCT05440630)
- Testing
- Probiotics, Postbiotic
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Healthy Nutrition
Sex Differences in Metabolism Following a High-fat Meal
Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2…
- Trial name
- HFM (NCT05332301)
- Testing
- High-fat test meal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsten Bell
Diet, Healthy, Body Weight
Diet-Induced Changes in GEnetic Material
This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in…
- Conditions
- Diet, Healthy, Body Weight, Metabolic Disturbance
- Trial name
- DIG 'EM (NCT06252922)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes Mellitus, Type 1
Effect of a Dietary Intervention on Insulin Requirements in Type 1 Diabetes
The purpose of this study is to compare the effects of a low-fat, plant-based dietary intervention and a portion-controlled dietary intervention (compliant with current American Diabetes Association (ADA) guidelines) on the…
- Trial name
- T1D (NCT04944316)
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Premature Infants
Infant Formula Supplemented With a Special Fat Formulation for Premature Infants Following Discharge From Hospital
The purpose of this study is to compare the efficacy and nutritional suitability of 2 infant formulas supplemented with different levels of LCPUFA, for premature infants following discharge from Hospital.
- Trial name
- NCT01140243
- Testing
- LCPUFA
- Where
- 2 sites in Israel
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Materna Laboratories
Sarcopenia, Cholecystectomy
The Relationship Among Sarcopenia, Preperitoneal Fat Thickness and Cholecystectomy
The aim of this study was to examine the relationship between sarcopenia and visceral adiposity in participants with and without cholecystectomy.
- Trial name
- NCT06468735
- Testing
- sarcopenia assessment, visceral fat thickness measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Obesity
Efficacy and Safety of Fermented Cinnamon Vine Powder on Decrement of Body Fat
The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fermented Cinnamon Vine Powde on decrement of body fat.
- Trial name
- NCT01734187
- Testing
- Fermented Cinnamon Vine Powder
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Diabetes, Exercise Physiology
Elevated FFA and Skeletal Muscle Lipid Content
There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events.
- Trial name
- NCT01906333
- Testing
- Exercise, Glucose, Fasted
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Overweight
Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study
Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy.
- Trial name
- P+RISE (NCT01960335)
- Testing
- Whey Protein, Whey Protein and Resistance Exericse, Whey Protein and RISE exercise routine
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Obesity, Taste Sensitivity
Genetics and Fat Taste Sensitivity
A cross-sectional quantitative study will be carried out; recruiting female, Caucasian participants aged 18-65 years. The relevance of candidate gene studies is disputed.
- Trial name
- NCT03666182
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Diabetes Mellitus, Type 2, Overweight
Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and…
- Trial name
- NCT00382473
- Testing
- Aerobic exercise program - 8 weeks
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Hypercholesterolemia, Hyperlipidemias
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol
This study will comprise a randomized controlled, counter-balanced, cross-over trial to evaluate the independent effects of a high cholesterol (high egg), low saturated fat diet and a high saturated fat, low cholesterol diet on…
- Conditions
- Hypercholesterolemia, Hyperlipidemias, Physical Inactivity, Diet, Healthy
- Trial name
- NCT05267522
- Testing
- Egg diet, Egg-free Diet, Control Diet
- Where
- Australia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of South Australia
Substrate Oxidation, Energy Expenditure
Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink
The purpose of this study is to evaluate acute changes in rates of fat oxidation during exercise with and without the ingestion of a caffeine-based energy drink.
- Conditions
- Substrate Oxidation, Energy Expenditure, Reaction Time, Cognition
- Trial name
- EDX (NCT06308731)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healthy
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects
The purpose of this trial is to demonstrate bioequivalence of a newly developed fixed dose combination (FDC) tablet containing empagliflozin and metformin extended release compared to the free combination of empagliflozin and…
- Trial name
- NCT02230995
- Testing
- metformin, empagliflozin/metformin, empagliflozin
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Menopause, Visceral Adipose Tissue Accumulation
Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation
The aim of this study is to develop an intervention that will produce a sustained improvement in physical activity and chronic stress as a means to slow the menopause-related accumulation of visceral adipose tissue in mid-life…
- Conditions
- Menopause, Visceral Adipose Tissue Accumulation, Abdominal Obesity, Obesity
- Trial name
- NCT01778712
- Testing
- Multi-level intervention
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Obesity
Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity
This study will investigate the effects of at least 12 weeks of weekly cold water immersions (water temperature 18ºC) on BAT perfusion in individuals with obesity.
- Trial name
- MOTORBAT (NCT05468151)
- Testing
- Cold acclimation, Intervention Control group - volunteers with obesity, Acute cold exposure
- Where
- Finland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Hypercholesterolemia
Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble Vitamins
The aim was to investigate the effects of the consumption of high doses of plant stanol esters on concentrations of serum lipids, carotenoids and fat soluble vitamins.
- Trial name
- maxsta (NCT00698256)
- Testing
- vegetable oil-based spread and oat-based drink (no brand name available)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Body Fat Disorder
Effects on Cellulite Appearance
Evaluate the safety and feasibility effecting the appearance of cellulite on the thigh using CoolSculpting.
- Trial name
- EFC (NCT04876118)
- Testing
- The ZELTIQ System
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Athletic Performance Enhancement, Body Composition Optimization
Effect of Plant vs Animal Protein Supplementation on Body Composition in Youth Soccer Players
This prospective, single-blind, randomized controlled trial investigates the comparative effects of plant-based protein (soy and rice blend) versus animal-based protein (whey) supplementation on body composition parameters in…
- Conditions
- Athletic Performance Enhancement, Body Composition Optimization, Nutritional Supplementation in Athletes
- Trial name
- PLANT-ANIMAL-P (NCT07571720)
- Testing
- Plant-Based Protein Supplement, Animal-Based Protein Supplement (Whey)
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez