Clinical trials: Body Fat
Childhood Obesity
Effect of Dietary Fat Cooking Blend on Energy Expenditure in Children
The purpose of this study is to test the effects of a cooking oil blend of dietary fats rich in medium chain triglycerides on energy expenditure and food intake in overweight and obese children.
- Trial name
- Melt (NCT01720589)
- Testing
- Melt (test oil), Corn oil (control)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Obesity
Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men
Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will be measured with the microdialysis technique by measuring glycerol concentration and blood flow in abdominal adipose tissue.
- Trial name
- NCT02211391
- Testing
- Casein Protein
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Inflammatory Bowel Disease
Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study
This is a Phase 1, open-label, 2-cohort, food-effect, DDI, and formulation bridging study.
- Trial name
- NCT03555617
- Testing
- TD-1473, Itraconazole
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Maxillary Sinus
Effect of Buccal Fat Pad and Platelet Rich Fibrin After Ultrasonic Hydrodynamic Maxillary Sinus Membrane Elevation
Placing implants in the posterior maxillary area has the drawback of working with scarce, poor quality bone in a significant percentage of cases.
- Trial name
- NCT04123860
- Testing
- ultrasonic hydrodynamic maxillary sinus lift buccal pad fat, ultrasonic hydrodynamic maxillary sinus lift platelet rich fibrin
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Moderate or Severe Submental Fullness
Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area
To evaluate the safety of deoxycholic acid subcutaneous injections in the submental area (below the chin).
- Trial name
- NCT01426373
- Testing
- Deoxycholic acid injection
- Where
- 18 sites in United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Moderate or Severe Submental Fullness
Determine the Dosing Interval and Optimal Dose of AYP-101 for the Reduction of Submental Fat in Chin Area
To determine the dosing interval, optimal dose, evaluate safety, and efficacy of AYP-101 S.C injection for the reduction of Submental Fat (SMF).
- Trial name
- NCT05266729
- Testing
- Polyene Phosphatidylcholine
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- AMIpharm Co., Ltd.
Healthy
A Study to Assess the Pharmacokinetics and Food Effect of SR419 in Healthy Subjects
This will be an open-label, single-site, Phase I study to evaluate the PK, safety, and tolerability of SR419 in healthy volunteers.
- Trial name
- NCT04705077
- Testing
- SR419
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- SIMR (Australia) Biotech Pty Ltd.
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
Obesity
Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRI
Background: It is important for doctors to know how much fat a person has in his or her body. Machines called DXAs measure how much fat mass and fat-free mass a person has.
- Trial name
- NCT02346474
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy, Obesity
Postprandial Inflammatory Response in Healthy Men: Effect of Dietary Fat Source, Obesity and Age
The nature of dietary lipids, age and perivisceral adiposity could alter the postprandial inflammatory response. It is supposed that there is a relationship between the postprandial inflammatory response and the repartition of…
- Trial name
- NCT01066091
- Testing
- Mashed potatoes, Mashed potatoes + Oleic acid, mashed potatoes + Palmitic acid
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Yves Boirie
Body Fat
Clinical Study to Evaluate the Body Fat Reducing Effects of Heat-Treated Green Tea Extract Complex
This clinical study was designed to evaluate the efficacy and safety of body fat reduction in obese adults by treatment of heat-treated green tea extract complex
- Trial name
- NCT06609603
- Testing
- HTGT compound
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Metabolic Syndrome
Acute Effects of Oral Carbohydrate and Fat Loads on Systemic Microvascular Endothelial Function in Healthy Individuals.
The present study was designed to evaluate vascular endothelial dysfunction resulting from the oral ingestion of high loads of sugar and fat meals in healthy individuals.
- Trial name
- NCT03515460
- Testing
- sugar oral load, fat oral load, sugar and fat oral load
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Central Abdominal Bulging
Evaluating the Safety and Efficacy of LIPO-202 for the Reduction of Central Abdominal Bulging Due to Subcutaneous Fat (AbCONTOUR2)
This is a multi-center, randomized, double-blinded, placebo-controlled study evaluating the safety and efficacy of LIPO-202 for the reduction of central abdominal bulging due to subcutaneous fat in non-obese subjects.
- Trial name
- NCT02398188
- Testing
- LIPO-202
- Where
- 35 sites in United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Overweight and Obesity, Fat Burn
Green Tea Supplementation, Fat Oxidation and Body Composition in Overweight Individuals
The purpose of this study is to investigate the effects of green tea extract (GTE) on fat oxidation, body composition and exercise performance in overweight individuals.
- Trial name
- GreenTea (NCT04628624)
- Testing
- GTE 1, GTE 2
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Cardiovascular Diseases, Inflammation
The Effects of Consuming Palm Oil With Different Macronutrient Intakes on Blood Lipids
The purpose of this study is to determine the effects of palm oil when consumed as either part of a low carbohydrate diet or a high carbohydrate diet on blood lipids, cardiovascular health and inflammation.
- Trial name
- NCT02922062
- Testing
- Canola Oil, Palm Oil, Butter
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Adipose Tissue, Brown Adipose Tissue
Cold Induced Activation of Brown Adipose Tissue in Winter Swimmers
This study investigates cold-induced brown fat activation in winter swimmers and not-winter swimmers by skin temperature measures assessed with infra red thermography imaging and skin temperatures.
- Conditions
- Adipose Tissue, Brown Adipose Tissue, Brown Fat, Uncoupling Protein 1
- Trial name
- COLDBAT_WS (NCT03095846)
- Testing
- Cooling
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Participants
Evaluate the Effects of Food on the Pharmacokinetics of SIM0270
This is a randomized, open label, single dose, two-period, crossover trial phase I study. The purpose of this study is to evaluate the food effect on the pharmacokinetics(PK) of SIM0270 after oral administration under fasted…
- Trial name
- NCT06536036
- Testing
- SIM0270
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Lipid Metabolism, Substrate Metabolism
Body Composition and Lipid Metabolism at Rest and During Exercise: A Cross-Sectional Analysis.
The ability to upregulate fat oxidation at appropriate times such as during fasting, low to moderate intensity exercise and after a high fat meal, is popularly advocated.
- Conditions
- Lipid Metabolism, Substrate Metabolism, Exercise
- Trial name
- NCT03029364
- Testing
- Study Protocol
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Bath
Obesity, Exercise
Exercise Training and Insulin Sensitivity
Regular exercise participation is known to reduce cardiometabolic disease risk but the impact that exercise training has on adipose tissue (AT) metabolism is poorly understood, particularly in humans.
- Trial name
- NCT05930834
- Testing
- exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
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