Clinical trials: Body Weight
Obesity and Obesity-related Medical Conditions
Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging.
We invite the participants to take a part in a research study conducted at the 2nd Department of General Surgery of the Jagiellonian University Medical College.
- Trial name
- NCT06618846
- Testing
- laparoscopic sleeve gastric bypass
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University Hospital in Krakow
Cachexia; Cancer, Anorexia
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.
Cancer-associated anorexia-cachexia is an insidious syndrome that has a major impact on the patient's quality of life, but is also associated with a significant reduction in survival.
- Trial name
- NCT03283488
- Testing
- Mirtazapine, Megestrol
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo
Morbid Obesity
Changes in Incretines, Gut Hormones and Bile Acids After Roux-en-Y Gastric Bypass
Obesity is an increasing world wide problem. Moreover, the increase in patients who are considered morbidly obese is even higher (Sturm et al, Healt Aff 2004).
- Trial name
- NCT03384303
- Testing
- Standardized meal test
- Volunteers
- 10 people
- Sponsor
- Rijnstate Hospital
Stroke
Development of an Intelligent Balance Training System Providing Weight-bearing Feedback in Stroke Patients
The sit-to-stand and dynamic weight-shifting ability of stroke patients is highly associated with walking performance. Therefore, in order to improve the dynamic weight-shifting ability in sit-to-stand and parallel or tandem…
- Trial name
- NCT04841161
- Testing
- Balance function, gait ability, weight- distribution and weight-shifting, Weight- distribution and weight-shifting training program
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Obesity
A Study of BGM0504 in Participants With Obesity
To evaluate the efficacy and safety of BGM0504 compared with Tirzepatide in adult participants who have obesity without diabetes after 26 weeks of treatment.
- Trial name
- NCT06911203
- Testing
- BGM0504, Tirzepatide
- Where
- China
- Volunteers
- 96 people
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Morbid Obesity
Dosing Obese With Noxafil® Under a Trial (DONUT)
Although posaconazole is approved for the prophylaxes and treatment of invasive fungal infections, specific dosing guidelines for posaconazole in (morbidly) obese patients are not specified.
- Trial name
- DONUT (NCT03246386)
- Testing
- Posaconazole Injection [Noxafil] 300mg, Posaconazole Injection [Noxafil] 400mg
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy, Obesity
Stearoyl-CoA Desaturase and Energy Metabolism in Humans
The aim of this study is to examine if changing stearoyl-coenzyme A desaturase-1 (SCD1) activity through dietary interventions can increase energy metabolism in humans.
- Trial name
- SEM (NCT02647970)
- Testing
- PUFA-Cys/Met diet, SFA+Cys/Met diet
- Where
- Norway
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Obesity
Effectiviteit en Beleving Van FooDIYou
Studies have shown that personalized nutrition advice is more effective compared to generic nutrition advice for weight loss purposes.
- Trial name
- NCT06547983
- Testing
- Personalized nutritional advice, Personalized nutritional advice and food boxes
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- TNO
Obesity
Effects of a Short-term Aerobic Interval Exercise Program on Cardiac Fat and Function in Women With Obesity: A Pilot Study
The overall goal of this project is to the study the effects of an aerobic interval training program on cardiac fat, and its relationship to cardiac function using cardiac Magnetic Resonance Imaging.
- Trial name
- NCT04802005
- Testing
- Aerobic Interval Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Southern Illinois University Edwardsville
Weight Loss
The Personalized Nutrition Study
A person's genetic code is believed to affect how much weight he/she will lose during diets that vary in carbohydrate and dietary fat content.
- Trial name
- POINTS (NCT04145466)
- Testing
- High-fat diet, High-carbohydrate diet
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Overweight, Type2 Diabetes
Hospital Workplace Nutrition Study
The purpose of this study is to evaluate the effects of a plant-based diet on body weight, blood pressure, and plasma lipid concentrations, as part of a hospital workplace program.
- Trial name
- NCT04222894
- Testing
- Plant-based diet, Control Diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Obesity, Morbid Obesity
Monitoring Obese Patients : Impact on the Frequency of Monitoring Weight
The literature data show that long-term monitoring has an effect on weight loss, comorbidity and on improving the quality of life.
- Conditions
- Obesity, Morbid Obesity, Quality of Life
- Trial name
- SUIVIOBESITE (NCT02374866)
- Testing
- closer monitoring
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Limoges
Heart Failure and Preserved Ejection Fraction, Obesity (Disorder)
OBESE-HFpEF: Towards Preventing Obesity Related HFpEF
Obesity, severe overweight, is a growing problem worldwide and increases the risk of heart failure, especially a type called heart failure with preserved ejection fraction (HFpEF). In HFpEF, the heart becomes stiffer.
- Conditions
- Heart Failure and Preserved Ejection Fraction, Obesity (Disorder), Heart Failure
- Trial name
- OBESE-HFpEF (NCT07539766)
- Where
- Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Obesity, Coronary Artery Disease
Effects of Aerobic Exercise in Obese Patients with Atherosclerotic Cardiovascular Disease
Obesity is classified using body mass index (BMI) (BMI ≥25 overweight, BMI ≥30 obese, BMI ≥40 morbidly obese). Obese patients are Class 1 according to BMI; BMI:30-34.9 and Class 2; BMI: It is classified as 35-39.9.
- Trial name
- NCT06318741
- Testing
- aerobic exercise on the treadmill+For both groups, patients will be recommended joint range of motion (ROM), stretching, strengthening, posture and balance and flexibility exercises for all joints., Walking at an intensity of 12-13 RPE+For both groups, patients will be recommended ROM, stretching, strengthening, posture and balance and flexibility exercises for all joints.
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kayseri City Hospital
Overweight, Hypertriglyceridemic Waist
Effect of Arginine Supplementation in the Metabolic Syndrome
The purpose of this study is to determine whether oral supplementation with one form of arginine improves vascular endothelial function in healthy subjects with risk factors associated with the metabolic syndrome
- Trial name
- NCT02354794
- Testing
- One form of arginine
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Metabolic Syndrome, Diabetes
Evaluation of a Novel Self-Sampling Earwax Tool for Chronic Disease Biomarkers [TREARS STUDIES II]
Trears Biomarkers: A New Way to Manage Chronic Diseases Trears Biomarkers are changing how we care for chronic diseases by focusing on patients' needs.
- Conditions
- Metabolic Syndrome, Diabetes, Hypertension, Obesity and Obesity-related Medical Conditions
- Trial name
- Trears-II (NCT06932601)
- Volunteers
- 258 people
- Sponsor
- Trears
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Pregnancy Related, Adolescent Obesity
#BabyLetsMove Physical Activity Feasibility Trial
Black adolescents who are pregnant represent a high-risk and understudied perinatal population in health research. Adolescent pregnancy (<20 years) is disproportionately prevalent among Blacks compared with Whites and is a…
- Conditions
- Pregnancy Related, Adolescent Obesity, Behavior, Health, Behavior, Sedentary
- Trial name
- NCT04628065
- Testing
- #BabyLetsMove
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Pain, Incontinence, Urinary
Sumamos Excelencia 2022
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Conditions
- Pain, Incontinence, Urinary, Obesity, Childhood, Breastfeeding
- Trial name
- NCT05466656
- Testing
- Continuous quality improvement cycle model
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Overweight or Obesity
A Proof of Concept Trial in Overweight and Obese Patients, Investigating Effect of EMP16-02 on Body Weight (Primary)
This study is a proof of concept study to demonstrate that EMP16-02, a fixed dose combination (FDC) of orlistat and acarbose in an oral multiple-unit modified release (MR) formulation leads to a clinically relevant decrease in…
- Trial name
- NCT04521751
- Testing
- EMP16-02 120 mg orlistat/40 mg acarbose, EMP16-02 150 mg orlistat/50 mg acarbose
- Where
- 2 sites in Sweden
- Volunteers
- 156 people
- Sponsor
- Empros Pharma AB