Clinical trials: Body Weight Changes
Obesity, Childhood
Improving Childhood Obesity-Related Behavior Change Through Better Risk Communication
One-third of American children are overweight or obese, leading to an increased risk for cardiovascular disease (CVD), early mortality, and other risks throughout their lifespan relative to normal weight children.
- Trial name
- NCT03074929
- Testing
- Novel risk communication
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Binge Eating Disorder, Overweight and Obesity
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
The purpose of this research is to conduct a randomized controlled trial (RCT) assessing the impact of CBT on neural responses to binge eating stimuli.
- Trial name
- NCT03604172
- Testing
- Cognitive behavioral therapy, Waitlist
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity
High Intensity Interval Circuit Training on Resting Metabolic Rate in Overweight Adults
This is the first study to examine changes in resting metabolic rate up to 72 hours following an exercise session, and how these changes may be affected by 12 weeks of high intensity interval circuit training (HIICT).
- Trial name
- NCT03972059
- Testing
- Exercise training - Phase 1, Exercise training - Phase 2, Exercise training - Phase 3
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Pregnancy
Assessment of the Nutritional Status of Pregnant Women and Optimization of Prenatal Care Services
A national survey in Niger found that women and children are at risk of undernutrition and that many pregnant women don't visit health centers during pregnancy as often as is recommended.
- Trial name
- NCT01832688
- Testing
- Programmatic prenatal care optimization
- Where
- Niger
- Volunteers
- 2,306 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy, Overweight
The Effect of Blood Volume Changes on the Glucose Tolerance
In this study the investigators would like to elaborate on the mechanisms that lead to a higher insulin sensitivity after exercise training and a lower insulin sensitivity after bedrest.
- Trial name
- BV-GT (NCT02612597)
- Testing
- Bedrest, Exercise Training
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carsten Lundby
Damage Muscle, Body Weight Changes
Chronic Study on Body Composition, Training, Performance, and Recovery
The chronic phase of the study will evaluate the effects of pre-exercise and post-exercise ingestion of a multi-ingredient supplement on adaptations to a 6-week exercise program consisting of both resistance training and high…
- Conditions
- Damage Muscle, Body Weight Changes, Performance Enhancing Product Use
- Trial name
- NCT04230824
- Testing
- Pre-workout plus and Protein recovery plus, 6-week resistance training program
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Infant, Premature, Diseases
Effect of Tactile-Kinesthetic Stimulation on Preterm Neonates
An interventional study to evaluate the effect of tactile-kinesthetic stimulation (TKS) on growth, neurobehavior and development among preterm neonates in the neonatal unit of Dr. Cipto Mangunkusumo Hospital.
- Trial name
- NCT04807088
- Testing
- Tactile-kinesthetic Stimulation
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Physical Activity, Sedentary Behavior
Teen Mom Study Feasibility Trial
The proposed multicomponent digital health intervention has the potential to significantly impact the trajectory of maternal health in a rural, pregnant, Black adolescent population with the highest risks for cardiometabolic…
- Conditions
- Physical Activity, Sedentary Behavior, Gestational Weight Gain, Social Determinants of Health
- Trial name
- NCT05843903
- Testing
- #BabyLetsMove
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Insulin Resistance, Metabolic Syndrome
Gene Expression in Obesity and Insulin Resistance
Lifestyle and genetic factors interact in the development of obesity and the metabolic syndrome. The molecular mechanisms underlying the beneficial dietary modifications are, however, unclear.
- Trial name
- Genobin (NCT00621205)
- Testing
- Weight reduction, Resistance training, Aerobic exercise training, Control
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Weight Loss
Effects of Two Weeks of 5:2 Intermittent Energy Restriction on Basal and Postprandial Metabolism
Worldwide, a third of adults were overweight in 2016, and 13% were obese. Excess energy intake results in weight gain. Excess fat increases the risk of disease (eg.
- Trial name
- NCT04138160
- Testing
- 5:2 Intermittent energy restriction, Continuous energy restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Healthy, Overweight
The Influence of Probiotics on Body Weight and Composition
The purpose of this study is to evaluate the addition of two different probiotic interventions to a comprehensive behavioral lifestyle intervention on body weight loss and overall health in overweight adults.
- Trial name
- WLP (NCT02465294)
- Testing
- Probiotic, Behavioral lifestyle intervention, Blood Test
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Weight Loss, Other Effects of High Altitude
Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization
This research will evaluate nutrition requirements for missions at high altitude (i.e. >7800 feet above sea level) and the information obtained can be used to optimize nutrient content specifications for combat rations.
- Trial name
- NCT02731066
- Testing
- Standard pro, High pro, carbo bev
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Abdominal Obesity, Metabolic Syndrome
Diet, Exercise, Metabolism, and Obesity in Older Women
Reductions in fat oxidation and resting metabolic rate (RMR) are associated with normal aging and are accelerated with menopause.
- Trial name
- DEMO (NCT00664729)
- Testing
- Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Overweight
Caloric Restriction and Body Weight in Adults
The purpose of this study is to determine the role of 1. dietary calcium in fecal fat loss and the association between lactose maldigestion, dietary calcium level and source, and weight loss induced by caloric restriction. 2.
- Trial name
- NCT00808275
- Testing
- Dietary calcium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Diet, Mediterranean, Health Behavior
Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits
The purpose of this study is to modify the food culture of the fire service by motivating firefighters and their families to incorporate Mediterranean diet principles at work and home through behavior change strategies that…
- Conditions
- Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
- Trial name
- NCT02941757
- Testing
- Mediterranean diet Intervention
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Goiter, Hypothyroidism
ThyrOp: A Study of Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic Goiter
The hypothesis of the study is that among patients that do not develop overt hypothyroidism after hemithyroidectomy, weight gain is a clinical manifestation of a postoperatively lowered set point of thyroid function - even if the…
- Conditions
- Goiter, Hypothyroidism, Weight Gain
- Trial name
- ThyrOp (NCT01358136)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Education, Asthma
Evaluating the Collaborative Management in Pediatrics (CMP) Training Program Among Pediatric Resident Doctors and Their Patients With Asthma or Obesity
Self-care behaviors are decisions and actions that people can take to improve their health or cope with a health problem. It is important for people with long-term illnesses to develop and maintain effective self-care behaviors.
- Conditions
- Education, Asthma, Obesity
- Trial name
- CMP (NCT00510341)
- Testing
- Collaborative Management in Pediatrics (CMP) Program
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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