Clinical trials: Body Weight Control
Obesity
Study of Coffee Mannooligosaccharides for Weight Management
The goal of this study is to establish the role of coffee mannooligosaccharides (MOS), provided in a beverage format, on body weight regulation.
- Trial name
- MOS (NCT00932750)
- Testing
- Coffee mannooligosaccharide, Coffee mannooligosaccharides
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Overweight and Obesity
Diet-Induced Variability in Appetite (DIVA)
The aim of this study is to test the hypothesis that dietary weight loss (WL) through alternate day fasting (ADF) will enhance appetite control, health markers and wellbeing following WL compared to standard daily calorie…
- Trial name
- DIVA (NCT03447600)
- Testing
- Alternate Day Fasting, Continuous dietary restriction
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Chronic Disease, Sedentary Lifestyle
Evidence-Based Lifestyle Prescription Program: Pilot Study
The HealtheSteps™ (HeS) Program is an evidence-based, community-focused, lifestyle prescription (Rx) program, supported by in-person coaching and innovative health technologies.
- Conditions
- Chronic Disease, Sedentary Lifestyle, Overweight
- Trial name
- HeSP (NCT02413385)
- Testing
- HealtheSteps Program
- Where
- Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Overweight, Obesity
Healthy Habits, Healthy Girls Preventing Unhealthy Weight Gain
The purpose of this study is to evaluate the impact of a multicomponent school-based intervention based on Bandura's Social Cognitive Theory targeting healthy eating and physical activity for high school adolescent girls from…
- Trial name
- NCT02228447
- Testing
- Healthy Habits, Healthy Girls Group
- Where
- Brazil
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Recurrent Spontaneous Abortion
Prospective Study of BMD and Ca-P Metabolism in RSA Patients: LMWH Use Versus Control
The goal of this prospective observational study is to learn about the effect of low molecular weight heparin (LMWH) application on bone mineral density (BMD) and on calcium-phosphorus metabolism in patients with recurrent…
- Trial name
- NCT05878574
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Obesity
A First-Time-In-Human Study in Healthy Subjects
This is a first-time-in-human study. The overall purpose of the study is to assess whether the drug is safe and well tolerated after single, increasing doses.
- Trial name
- FTIH (NCT00857883)
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Overweight, Obesity
Nutrition, Exercise, and Technology for Weight Loss
The purpose of this study is to evaluate whether a social support-enhanced, technology-based, behavioral weight control intervention can improve weight loss over existing best practices.
- Trial name
- NCT02731768
- Testing
- Standard, Social support-enhanced, Fitbit Zip
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity, Child
The PAC Study: Parents as Agents of Change in Pediatric Weight Management
The Canadian pediatric obesity epidemic has led to great interest in evaluating weight management care for obese children and families.
- Trial name
- PAC (NCT01267097)
- Testing
- Cognitive Behavioural Therapy (CBT), Psycho-Education Program (PEP)
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obesity and Obesity-related Medical Conditions
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
This study is designed to test how well the combination of MET233 with MET097 works to treat individuals with obesity or overweight with or without diabetes.
- Trial name
- NCT06924320
- Testing
- MET233 and MET097, MET097
- Where
- United States
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Pfizer
Adolescent Behavior
The "Fortaleça Sua Saúde" Program for Active and Healthy Lifestyle Among Brazilian Students
Background: Interventions on lifestyle among adolescents are important, but the main mechanisms that explain the changes (mediating variables) on lifestyle have been little explored.
- Trial name
- NCT02439827
- Testing
- "Fortaleça sua Saúde" program
- Volunteers
- 1,085 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Cachexia
Safety, Tolerability, Pharmacokinetic (PK), and Pharmacodynamic Study of GSK2881078 and Study to Evaluate the Effect of CYP3A4 Inhibition on PK of GSK2881078
GSK2881078 is a selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function.
- Trial name
- NCT02567773
- Testing
- GSK2881078, Itraconazole
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Visceral Fat
The Healthy Diet and Lifestyle Study
This pilot study aims to develop a study design to test the difference between a fasting diet and a heart healthy diet, assess participants' adherence to the study design, and to test whether either diet helps to reduce fat…
- Trial name
- HDL (NCT03639350)
- Testing
- IER+MED group, DASH group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Overweight and Obesity
EXerCise wEight Loss
The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.
- Trial name
- EXCEL (NCT05702840)
- Testing
- Resistance exercise training + weight loss group, Weight loss only group (WL)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Diabetes Mellitus, Chronic Disease
Meta-analyses of Liquid Versus Solid Calories and Body Weight
Consumption of sugar-sweetened beverages (SSBs) has been linked to rising rates of overweight and obesity. The most prominent mechanism to explain the link between SSBs and obesity is that liquid calories are not perceived by the…
- Conditions
- Diabetes Mellitus, Chronic Disease, Cardiovascular Diseases, Prediabetic State
- Trial name
- NCT02702440
- Testing
- Liquid calories from sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Weight Gain, Overweight
Evaluation of the Effect of Two Online Interventions -Watch Your Weight During the Holidays Program and the Relative 5:2 Fasting- for the Prevention of Body Weight Gain at 8 Weeks in Mexican Adults in the Covid-19 Pandemic
Introduction. Obesity is the main risk factor for the development of chronic degenerative diseases in Mexico and other countries around the world.
- Conditions
- Weight Gain, Overweight, Obesity
- Trial name
- NCT05060978
- Testing
- Watch your Weight During the Holidays Program, Relative 5:2 Fasting, Control Group
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Obesity, Impaired Health
Effectiveness of a Smartphone App for Adolescent Obesity Management
Though face-to-face treatment of childhood obesity can be effective, it is time consuming and costly. This study will test whether treatment can be delivered via an Android app and whether such treatment reduces obesity.
- Conditions
- Obesity, Impaired Health, Psychosocial Problem, Physical Activity
- Trial name
- NCT01804855
- Testing
- W82GO, smartphone application
- Where
- 2 sites in Ireland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's University Hospital, Ireland
Smoking, Body Weight
Treating Adults at Risk for Weight Gain With Interactive Technology
Obesity represents a chronic disease associated with significant cardiovascular disease (CVD) morbidity and mortality. Weight gain in young adults adversely impacts the development of CVD risk factors.
- Trial name
- TARGIT (NCT01199185)
- Testing
- Smoking Cessation, Smoking Cessation plus Weight Loss
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Obesity, Overweight
A Trial of One to One Weight Management in Primary Care
The purpose of this study is to conduct a randomised controlled trial to assess the sustained effects on weight, selected risk factors and sense of well-being of offering individualized weight management advice in the primary…
- Trial name
- NCT00891943
- Testing
- Structured lifestyle support
- Where
- 2 sites in United Kingdom
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Overweight (BMI > 25), Weight Loss
The Impact of Salmon Protein Hydrolysate (SPH / ProGo®) Supplementation on Hematologic and Metabolic Health
Healthy, overweight males and females randomised to receive 8-weeks of salmon protein hydrolysate SPH (12g daily) or whey protein isolate (12g daily) to assess the impact on red blood cell and ferritin levels, blood glucose…
- Trial name
- NCT07616752
- Testing
- Nutritional supplementation, Nutritional Supplement
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Obesity, Childhood
Healthy Bodies Project to Prevent Childhood Obesity
The goal of this study is to evaluate components of a preschool-based intervention designed to (1) increase children's nutrition knowledge, (2) increase physical activity in childcare settings, (3) increase emotional, behavioral…
- Trial name
- Healthy Bodies (NCT04552678)
- Testing
- Healthy Eating, Active Play, Self-Regulation, Parent Education, Healthy Eating, Active Play, Self-Regulation, Healthy Eating, Active Play, Parent Education
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- Penn State University
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